Article
Orthopedics
Zhirong Zheng, Chao Liu, Zhen Zhang, Wenhao Hu, Meng Gao, Chengqi Jia, Xuesong Zhang
Summary: This study found that low DCTL may be a risk factor for thoracolumbar compression fractures in postmenopausal women, and a DCTL <= 8.7 degrees can be a threshold value for thoracolumbar compression fractures.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2021)
Article
Orthopedics
Zhisheng Long, Feipeng Gong, Long Xiong, Jiabin Wen, Gang Chen
Summary: This study provides clinical evidence to support the use of modified posterior osteotomy for treating osteoporotic vertebral collapse with delayed neurological dysfunction. The technique effectively preserves vertebral height, increases vertebral canal volume, corrects kyphotic angle, and improves postoperative neurological function. The simplified osteotomy also offers advantages in terms of operating time, blood loss, postoperative VAS score, and improvement in lumbar function.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Article
Oncology
Rui Guo, Bo Li, Ziliang Zeng, Xu Jiang, Di Zhang, Tianyu Xie, Xumin Hu, Liangbin Gao
Summary: The study revealed that in postmenopausal osteoporosis women, thoracolumbar kyphosis is related to reduced bone mineral density, and BMD can predict the occurrence of TLK. Factors such as BMD, PINP, bone alkaline phosphatase, and 25-(OH)D were identified as independent risk factors for future TLK in postmenopausal women. When the BMD(L) T-score is less than -1.65, postmenopausal women are more likely to develop TLK in the future.
ANNALS OF TRANSLATIONAL MEDICINE
(2022)
Article
Geriatrics & Gerontology
Shu-Bao Zhang, Hao Chen, Hao-Wei Xu, Yu-Yang Yi, Xin-Yue Fang, Shan-Jin Wang
Summary: This study found that decreased L3 PMD is an independent risk predictor of subsequent vertebral fractures (SVF). Combining L1 BMD and L3 PMD from CT scans can significantly improve the accuracy of predicting SVF risk in postmenopausal women who have experienced prior osteoporotic vertebral fractures.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2022)
Article
Orthopedics
Feng Liu, Hongmei Zhu, Jinlian Ma, Liqiong Miao, Shuang Chen, Zijie Yin, Huan Wang
Summary: This study evaluated the performance of iCare QCT compared with Mindways QCT in the detection of osteoporosis. The results showed no significant difference between iCare QCT and Mindways QCT in the evaluation of vertebral bodies L1, L2, and L3 in the European spine phantom (ESP). There was a strong correlation between iCare QCT and Mindways QCT in the assessment of hip T-score. iCare QCT had a higher detection rate of osteoporosis with hip T-score assessment compared to Mindways QCT.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Article
Medicine, General & Internal
Jan-Christoph Backhauss, Olav Jansen, Hans-Ulrich Kauczor, Sam Sedaghat
Summary: This study investigated the association between non-traumatic vertebral body fractures and degenerative changes in older patients. The results show that fatty deposits in the lower thoracic and lumbar spine are associated with non-traumatic fractures of the lower thoracic spine, but not with lumbar spine fractures.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hui Yang, Sheng Yan, Jiang Li, Xiuzhu Zheng, Qianqian Yao, Shaofeng Duan, Jianzhong Zhu, Changqin Li, Jian Qin
Summary: This study aimed to distinguish between acute and chronic osteoporotic vertebral fractures using radiomics-clinical analysis based on CT imaging. The results showed that the quantitative predictive models based on radiomic features and clinical fracture line feature had good predictive ability.
EUROPEAN JOURNAL OF RADIOLOGY
(2022)
Article
Endocrinology & Metabolism
D-P Kuo, Y-W Chiu, P-T Chen, Y-J Tsai, C-H Hou, Y-L Chen, C-M Chu
Summary: This study found that postmenopausal women with vertebral fractures had a higher risk associated with older age, shorter height, and lighter weight, with higher BMI observed in those with fractures. Women with osteoporosis were older and had lower height, weight, and BMD compared to those with normal bone health. Lower T-scores and bone mass were significant predictors of vertebral fracture risk.
OSTEOPOROSIS INTERNATIONAL
(2022)
Article
Endocrinology & Metabolism
Cristiana Cipriani, Salvatore Minisola, John P. Bilezikian, Davide Diacinti, Luciano Colangelo, Valentina Piazzolla, Maurizio Angelozzi, Luciano Nieddu, Jessica Pepe, Daniele Diacinti
Summary: In postmenopausal women with chronic postsurgical hypoparathyroidism, vertebral fractures can be detected by vertebral fracture assessment (VFA) despite normal bone mineral density values.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Medicine, General & Internal
You-Di Xue, Zhao-Chuan Zhang, Wei-Xiang Dai
Summary: Preoperative traction followed by percutaneous kyphoplasty combined with percutaneous cement discoplasty is an effective and simple procedure for treating severe thoracolumbar osteoporotic vertebral compression fractures, with satisfactory short-term clinical outcomes in relieving pain and improving kyphosis.
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
(2021)
Article
Endocrinology & Metabolism
Jean-Michel Pouilles, Anna Gosset, Alice Breteau, Florence Anne Tremollieres
Summary: In early postmenopausal women with severe vertebral osteoporosis, TBS values are proportional to BMD. Osteoporosis in this population is more likely a result of low peak bone mass, while the bone microstructure in older osteoporotic women is significantly affected by aging.
Review
Clinical Neurology
Philipp Pieroh, Ulrich J. A. Spiegl, Anna Voelker, Sven Maerdian, Nicolas H. von der Hoeh, Georg Osterhoff, Christoph-E. Heyde
Summary: This systematic review evaluated the effectiveness of spinal orthoses in the treatment of osteoporotic vertebral fractures (OVF). The results showed that studies without comparison groups reported improvements in pain, function, and quality of life. However, compared to patients not wearing an orthosis, some studies failed to find benefits, while two studies reported a significant improvement using an orthosis. Overall, there is currently no evidence of superiority for spinal orthoses in the treatment of OVF.
GLOBAL SPINE JOURNAL
(2023)
Article
Endocrinology & Metabolism
Wenting Qi, Yan Jiang, Wei Liu, Yue Chi, Ruizhi Jiajue, Qianqian Pang, Ou Wang, Mei Li, Xiaoping Xing, Wei Yu, Weibo Xia
Summary: Obesity is associated with improved areal bone mineral density, bone geometry, and bone microarchitecture in postmenopausal Chinese women. Except for a lower level of osteocalcin, no significant differences in bone turnover markers were found among the groups.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Medicine, General & Internal
Carolyn J. Crandall, Rebecca P. Hunt, Andrea Z. LaCroix, John A. Robbins, Jean Wactawski-Wende, Karen C. Johnson, Maryam Sattari, Katie L. Stone, Julie C. Weitlauf, Tanya R. Gure, Jane A. Cauley
Summary: This study prospectively analyzed the association between subsequent fractures in postmenopausal women after initial fractures at different sites. The results showed that different types of initial fractures increased the risk of subsequent fractures of different types, and this risk was observed across all age groups of women.
Article
Orthopedics
Zhirong Zheng, Wenhao Hu, Tian Tian, Weibo Liu, Xiangyu Wang, Meng Gao, Yonggang You, Xuesong Zhang
Summary: This study aimed to determine the relationship between vertebral compression fractures and thoracolumbar hyperflexion Cobb angles (TLHCobb) and identify the clinical cut-off of TLHCobb angle. The results showed that TLHCobb angles greater than 20.05 degrees were associated with an increased prevalence of vertebral fractures in postmenopausal women.
ORTHOPAEDIC SURGERY
(2023)