Journal
ORGANOMETALLICS
Volume 36, Issue 22, Pages 4465-4476Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.organomet.7b00702
Keywords
-
Categories
Funding
- MINECO [CTQ2015-69568-P]
- Fundacion Seneca [19890/GERM/15]
- NSERC Canada
- Alphora Inc.
- University of Toronto
Ask authors/readers for more resources
We have studied the possible reaction pathways operating in the Pd-catalyzed remote C-H functionalization of N-(2-haloaryl)acrylamides from an organometallic approach. We have isolated and characterized several proposed reaction intermediates, such as sigma-alkyl-Pd complexes and spiro C,C-palladacycles, and evaluated the role of the base and the auxiliary ligands coordinated to Pd in the remote C-H activation process. In addition, the reactivity of these intermediates toward different unsaturated species such as benzyne, alkynes, and isocyanides has been studied in order to gain further insight into the reaction mechanism leading to functionalized spiro-oxoindoles.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available