4.6 Article

Sustainable Flow Synthesis of a Versatile Cyclopentenone Building Block

Journal

ORGANIC PROCESS RESEARCH & DEVELOPMENT
Volume 21, Issue 12, Pages 2052-2059

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.oprd.7b00328

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Funding

  1. Royal Society
  2. Chinese Science Council

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A flow based multistep processing sequence to reliably provide the delivery of a highly functional cyclopentenone is described. The exemplification of employing solid dosing of reagents and in-line aqueous extraction has enabled an integrated workflow in a highly automated reactor setup.

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