Journal
ORGANIC LETTERS
Volume 19, Issue 18, Pages 4996-4999Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b02511
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [21572027, 21372267]
Ask authors/readers for more resources
A unified modular synthetic strategy has been developed for the first total synthesis of dictyodendrins G and synthesis of dictyodendrin F, H and I in 11 steps. The synthesis features consecutive functionalization of the core aminoquinone by palladium-mediated Suzuki Miyaura coupling reaction, 1,4-addition, acylation and base mediated formation of a pyrrolinone, and the formation of carbazolequinone moiety through a formal [3 + 2] cydoaddition using arynes generated in situ. Several dictyodendrin analogues were also synthesized using this strategy.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available