4.6 Article

Cationic phthalocyanine dendrimers as potential antimicrobial photosensitisers

Journal

ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 15, Issue 42, Pages 9008-9017

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7ob02270k

Keywords

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Funding

  1. Spanish Ministerio de Economia y Competitividad [CTQ2013-48767-C3-1-R, CTQ2014-52869-P, CTQ2016-78454-C2-1-R]
  2. Comunidad de Madrid (FOTOCARBON) [S2013/MIT-2841]
  3. Universidad Autonoma de Madrid, Spain

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In the present study we describe the synthesis, photophysical properties and the photoinactivation performance against representative microorganisms of two families of cationic dendrimeric phthalocyanines as potential photosensitisers. Four charged dendrimeric compounds varying in their degree of ionicity (4 or 8 positive charges) and the coordinating metal (zinc or ruthenium) are compared and assessed as potential photosensitising agents in terms of their antimicrobial activity.

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