An ortho C-methylation/O-glycosylation motif on a hydroxy-coumarin scaffold, selectively installed by biocatalysis

Crystal Structure and Catalytic Mechanism of CouO, a Versatile C-Methyltransferase from Streptomyces rishiriensis

(2017) Tea Pavkov-Keller et al.   PLoS One

AdoMet analog synthesis and utilization: current state of the art

(2016) Tyler D Huber et al.   CURRENT OPINION IN BIOTECHNOLOGY

Probing the Catalytic Promiscuity of a Regio- and Stereospecific C-Glycosyltransferase fromMangifera indica

(2015) Dawei Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Creating a Water-Soluble Resveratrol-Based Antioxidant by Site-Selective Enzymatic Glucosylation

(2015) Alexander Lepak et al.   CHEMBIOCHEM

Site-specific bioalkylation of rapamycin by the RapM 16-O-methyltransferase

(2015) Brian J. C. Law et al.   Chemical Science

Structure and mechanism of an antibiotics-synthesizing 3-hydroxykynurenine C-methyltransferase

(2015) Sheng-Chia Chen et al.   Scientific Reports

Facile Chemoenzymatic Strategies for the Synthesis and Utilization ofS-Adenosyl-L-Methionine Analogues

(2014) Shanteri Singh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A two-step O- to C-glycosidic bond rearrangement using complementary glycosyltransferase activities

(2014) Alexander Gutmann et al.   CHEMICAL COMMUNICATIONS

Methylation and subsequent glycosylation of 7,8-dihydroxyflavone

(2014) Niranjan Koirala et al.   JOURNAL OF BIOTECHNOLOGY

Profound Methyl Effects in Drug Discovery and a Call for New CH Methylation Reactions

(2013) Heike Schönherr et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Alkylating enzymes

(2013) Ludger A Wessjohann et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

New aminocoumarin antibiotics as gyrase inhibitors

(2013) Lutz Heide   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

S-Adenosyl-Methionine-Dependent Methyltransferases: Highly Versatile Enzymes in Biocatalysis, Biosynthesis and Other Biotechnological Applications

(2012) Anna-Winona Struck et al.   CHEMBIOCHEM

Expanding nature's small molecule diversity via in vitro biosynthetic pathway engineering

(2012) Seok Joon Kwon et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Molecular characterization of the C-methyltransferase NovO of Streptomyces spheroides, a valuable enzyme for performing Friedel–Crafts alkylation

(2012) Martin Tengg et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Architectures, mechanisms and molecular evolution of natural product methyltransferases

(2012) David K. Liscombe et al.   NATURAL PRODUCT REPORTS

RecombinantE. coliPrototype Strains forin VivoGlycorandomization

(2010) Gavin J. Williams et al.   ACS Chemical Biology

Improved vanillin production in baker's yeast through in silico design

(2010) Ana Brochado et al.   Microbial Cell Factories

Post-PKS tailoring steps in natural product-producing actinomycetes from the perspective of combinatorial biosynthesis

(2010) Carlos Olano et al.   NATURAL PRODUCT REPORTS

Cloning and heterologous expression of glycosyltransferases from Malus x domestica and Pyrus communis, which convert phloretin to phloretin 2′-O-glucoside (phloridzin)

(2010) Christian Gosch et al.   PLANT SCIENCE

Biocatalytic Friedel-Crafts Alkylation Using Non-natural Cofactors

(2009) Harald Stecher et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biosynthesis of Sibiromycin, a Potent Antitumor Antibiotic

(2009) W. Li et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Transcriptional regulation of the novobiocin biosynthetic gene cluster

(2009) V. Dangel et al.   MICROBIOLOGY-SGM

Probing the Aglycon Promiscuity of an Engineered Glycosyltransferase

(2008) Richard W. Gantt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Natural-Product Sugar Biosynthesis and Enzymatic Glycodiversification

(2008) Christopher J. Thibodeaux et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION