KLF6 depletion promotes NF-κB signaling in glioblastoma

USP18 lack in microglia causes destructive interferonopathy of the mouse brain

(2015) T. Goldmann et al.   EMBO JOURNAL

Increased H3K9me3 drives dedifferentiated phenotype via KLF6 repression in liposarcoma

(2015) Emily Z. Keung et al.   JOURNAL OF CLINICAL INVESTIGATION

Down-modulation of Bis reduces the invasive ability of glioma cells induced by TPA, through NF-κB mediated activation of MMP-9

(2014) Young Dae Lee et al.   BMB Reports

miR-101 Acts as a Tumor Suppressor by Targeting Kruppel-like Factor 6 in Glioblastoma Stem Cells

(2014) Yi-Long Yao et al.   CNS Neuroscience & Therapeutics

Krüppel-like Factor 6 Is a Co-activator of NF-κB That Mediates p65-dependent Transcription of Selected Downstream Genes

(2014) Yu Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kruppel-like Transcription Factor 6 Regulates Inflammatory Macrophage Polarization

(2014) Dipali Date et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression

(2014) Roberto Ferrarese et al.   JOURNAL OF CLINICAL INVESTIGATION

IHC Profiler: An Open Source Plugin for the Quantitative Evaluation and Automated Scoring of Immunohistochemistry Images of Human Tissue Samples

(2014) Frency Varghese et al.   PLoS One

Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma

(2013) Krishna P.L. Bhat et al.   CANCER CELL

Inhibition of NF- B Signaling Ablates the Invasive Phenotype of Glioblastoma

(2013) M.-A. Westhoff et al.   MOLECULAR CANCER RESEARCH

The NF-κB RelB Protein Is an Oncogenic Driver of Mesenchymal Glioma

(2013) Dong Whan Lee et al.   PLoS One

Transcription of Tnfaip3 Is Regulated by NF-κB and p38 via C/EBPβ in Activated Macrophages

(2013) Ting-Yu Lai et al.   PLoS One

KLF6-SV1 Drives Breast Cancer Metastasis and Is Associated with Poor Survival

(2013) R. Hatami et al.   Science Translational Medicine

Identification of DR5 as a critical, NF-κB-regulated mediator of Smac-induced apoptosis

(2013) I Eckhardt et al.   Cell Death & Disease

Krüppel-like factor 6 (KLF6) promotes cell proliferation in skeletal myoblasts in response to TGFβ/Smad3 signaling

(2013) Mathew G Dionyssiou et al.   Skeletal Muscle

PPARγ and NF-κB regulate the gene promoter activity of their shared repressor, TNIP1

(2011) Igor Gurevich et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Correlation of Somatic Mutation and Expression Identifies Genes Important in Human Glioblastoma Progression and Survival

(2011) D. L. Masica et al.   CANCER RESEARCH

Identification of a novel pro-apoptotic role of NF-κB in the regulation of TRAIL- and CD95-mediated apoptosis of glioblastoma cells

(2011) C Jennewein et al.   ONCOGENE

Blockade of the NFκB pathway drives differentiating glioblastoma-initiating cells into senescence both in vitro and in vivo

(2011) L Nogueira et al.   ONCOGENE

GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers

(2011) Craig H Mermel et al.   GENOME BIOLOGY

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

NFKBIADeletion in Glioblastomas

(2010) Markus Bredel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nucleo-Cytoplasmic Localization Domains Regulate Krüppel-Like Factor 6 (KLF6) Protein Stability and Tumor Suppressor Function

(2010) Estefanía Rodríguez et al.   PLoS One

KLF6-SV1 Is a Novel Antiapoptotic Protein That Targets the BH3-Only Protein NOXA for Degradation and Whose Inhibition Extends Survival in an Ovarian Cancer Model

(2009) A. DiFeo et al.   CANCER RESEARCH

Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma

(2009) Mara Compagno et al.   NATURE

The transcriptional network for mesenchymal transformation of brain tumours

(2009) Maria Stella Carro et al.   NATURE

Nuclear factor-κB activation and differential expression of survivin and Bcl-2 in human grade 2-4 astrocytomas

(2008) Filippo F. Angileri et al.   CANCER

A Functional Role for KLF6-SV1 in Lung Adenocarcinoma Prognosis and Chemotherapy Response

(2008) A. DiFeo et al.   CANCER RESEARCH

The role of KLF6 and its splice variants in cancer therapy

(2008) Analisa DiFeo et al.   DRUG RESISTANCE UPDATES

KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis

(2008) Goutham Narla et al.   JOURNAL OF CLINICAL INVESTIGATION