Nucleus accumbens-associated protein-1 promotes glycolysis and survival of hypoxic tumor cells via the HDAC4-HIF-1α axis

eEF-2 kinase is a critical regulator of Warburg effect through controlling PP2A-A synthesis

(2016) Y Cheng et al.   ONCOGENE

Nac1 Coordinates a Sub-network of Pluripotency Factors to Regulate Embryonic Stem Cell Differentiation

(2016) Mohan Malleshaiah et al.   Cell Reports

Glycolysis-Mediated Changes in Acetyl-CoA and Histone Acetylation Control the Early Differentiation of Embryonic Stem Cells

(2015) Arieh Moussaieff et al.   Cell Metabolism

Intrinsic bevacizumab resistance is associated with prolonged activation of autocrine VEGF signaling and hypoxia tolerance in colorectal cancer cells and can be overcome by nintedanib, a small molecule angiokinase inhibitor.

(2015) Paul Mésange et al.   Oncotarget

Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas

(2014) Fred Fack et al.   ACTA NEUROPATHOLOGICA

Nac1 interacts with the POZ-domain transcription factor, Miz1

(2014) Mark A. Stead et al.   BIOSCIENCE REPORTS

Parathyroid Hormone Regulates Histone Deacetylase (HDAC) 4 through Protein Kinase A-mediated Phosphorylation and Dephosphorylation in Osteoblastic Cells

(2014) Emi Shimizu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting vascular sprouts

(2014) L. B. Rivera et al.   SCIENCE

NAC1, A POZ/BTB protein interacts with Parkin and may contribute to Parkinson’s disease

(2013) L. Korutla et al.   NEUROSCIENCE

Fatty acid synthase expression associated with NAC1 is a potential therapeutic target in ovarian clear cell carcinomas

(2012) M T Rahman et al.   BRITISH JOURNAL OF CANCER

Dysfunction of Nucleus Accumbens-1 Activates Cellular Senescence and Inhibits Tumor Cell Proliferation and Oncogenesis

(2012) Yi Zhang et al.   CANCER RESEARCH

NAC1 Is an Actin-Binding Protein That Is Essential for Effective Cytokinesis in Cancer Cells

(2012) Kai Lee Yap et al.   CANCER RESEARCH

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

HIF1α Protein Stability Is Increased by Acetylation at Lysine 709

(2012) Hao Geng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting the Insulin Growth Factor and the Vascular Endothelial Growth Factor Pathways in Ovarian Cancer

(2012) M. Shao et al.   MOLECULAR CANCER THERAPEUTICS

Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation

(2012) N. Shyh-Chang et al.   SCIENCE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Biological and clinical significance of NAC1 expression in cervical carcinomas: a comparative study between squamous cell carcinomas and adenocarcinomas/adenosquamous carcinomas

(2011) Shamima Yeasmin et al.   HUMAN PATHOLOGY

HDAC4 Protein Regulates HIF1α Protein Lysine Acetylation and Cancer Cell Response to Hypoxia

(2011) Hao Geng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amplification of the ch19p13.2 NACC1 locus in ovarian high-grade serous carcinoma

(2011) Ie-Ming Shih et al.   MODERN PATHOLOGY

NAC1 modulates sensitivity of ovarian cancer cells to cisplatin by altering the HMGB1-mediated autophagic response

(2011) Y Zhang et al.   ONCOGENE

Biological role and prognostic significance of NAC1 in ovarian cancer

(2010) Kentaro Nakayama et al.   GYNECOLOGIC ONCOLOGY

Ubiquitin-dependent degradation of HDAC4, a new regulator of random cell motility

(2010) Nadia Cernotta et al.   MOLECULAR BIOLOGY OF THE CELL

Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α

(2010) Ji-Hong Lim et al.   MOLECULAR CELL

Expression of Fatty Acid Synthase Depends on NAC1 and Is Associated with Recurrent Ovarian Serous Carcinomas

(2010) Stefanie M. Ueda et al.   Journal of Oncology

Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition

(2009) A. Rapisarda et al.   MOLECULAR CANCER THERAPEUTICS

NAC-1, a potential stem cell pluripotency factor, contributes to paclitaxel resistance in ovarian cancer through inactivating Gadd45 pathway

(2009) N Jinawath et al.   ONCOGENE

An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells

(2008) Jonghwan Kim et al.   CELL

Phosphorylated ERα, HIF-1α, and MAPK Signaling As Predictors of Primary Endocrine Treatment Response and Resistance in Patients With Breast Cancer

(2008) Daniele Generali et al.   JOURNAL OF CLINICAL ONCOLOGY

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL