Loss of PRP4K drives anoikis resistance in part by dysregulation of epidermal growth factor receptor endosomal trafficking

The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR

(2016) Sandra Scharaw et al.   JOURNAL OF CELL BIOLOGY

PRP4K is a HER2-regulated modifier of taxane sensitivity

(2015) Dale P Corkery et al.   CELL CYCLE

Integrin endosomal signalling suppresses anoikis

(2015) Jonna Alanko et al.   NATURE CELL BIOLOGY

Nuclear domain ‘knock-in’ screen for the evaluation and identification of small molecule enhancers of CRISPR-based genome editing

(2015) Jordan Pinder et al.   NUCLEIC ACIDS RESEARCH

Natural killer T cell activation overcomes immunosuppression to enhance clearance of postsurgical breast cancer metastasis in mice

(2015) Simon Gebremeskel et al.   OncoImmunology

Both Decreased and Increased SRPK1 Levels Promote Cancer by Interfering with PHLPP-Mediated Dephosphorylation of Akt

(2014) Pingping Wang et al.   MOLECULAR CELL

Anoikis resistance is a critical feature of highly aggressive ovarian cancer cells

(2014) Q Cai et al.   ONCOGENE

Anoikis molecular pathways and its role in cancer progression

(2013) Paolo Paoli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

EGF receptor trafficking: consequences for signaling and cancer

(2013) Alejandra Tomas et al.   TRENDS IN CELL BIOLOGY

Getting to Know Ovarian Cancer Ascites: Opportunities for Targeted Therapy-Based Translational Research

(2013) Nuzhat Ahmed et al.   Frontiers in Oncology

Derivation and characterization of matched cell lines from primary and recurrent serous ovarian cancer

(2012) Isabelle J Létourneau et al.   BMC CANCER

Improving FRET dynamic range with bright green and red fluorescent proteins

(2012) Amy J Lam et al.   NATURE METHODS

BTN3A2 Expression in Epithelial Ovarian Cancer Is Associated with Higher Tumor Infiltrating T Cells and a Better Prognosis

(2012) Cécile Le Page et al.   PLoS One

Leukaemia xenotransplantation in zebrafish - chemotherapy response assay in vivo

(2011) Dale P. Corkery et al.   BRITISH JOURNAL OF HAEMATOLOGY

Integrated genomic analyses of ovarian carcinoma

(2011) D. Bell et al.   NATURE

Zeb1 is required for TrkB-induced epithelial-mesenchymal transition, anoikis resistance and metastasis

(2011) M A Smit et al.   ONCOGENE

ErbB2 Stabilizes Epidermal Growth Factor Receptor (EGFR) Expression via Erk and Sprouty2 in Extracellular Matrix-detached Cells

(2010) Alexandra R. Grassian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation

(2010) Marc Schneider et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Three common polymorphisms in theCYBAgene form a haplotype associated with decreased ROS generation

(2009) Karen Bedard et al.   HUMAN MUTATION

A Twist-Snail Axis Critical for TrkB-Induced Epithelial-Mesenchymal Transition-Like Transformation, Anoikis Resistance, and Metastasis

(2009) M. A. Smit et al.   MOLECULAR AND CELLULAR BIOLOGY

Redox regulation of anoikis: reactive oxygen species as essential mediators of cell survival

(2008) E Giannoni et al.   CELL DEATH AND DIFFERENTIATION