Article
Surgery
Ryan Howard, Grace F. Chao, Jie Yang, Jyothi R. Thumma, David E. Arterburn, Dana A. Telem, Justin B. Dimick
Summary: This study compared the incidence of medication discontinuation and restart after sleeve gastrectomy or gastric bypass over a period of 5 years. The results showed that gastric bypass was associated with a slightly higher incidence of medication discontinuation and a slightly lower incidence of medication restart among patients who discontinued medication.
Article
Surgery
Theofano Zoumpou, Aaron Fleishman, Daniel B. Jones, Christina C. Wee
Summary: This study found that a small percentage of sleeve gastrectomy (SG) patients (7%) expressed regret up to 6 years postoperatively, consistent with other research findings. Those who regretted the decision reported poorer quality of life, as well as lower weight loss and less improvement in physical health.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Multidisciplinary Sciences
Nadejda Bozadjieva-Kramer, Jae Hoon Shin, Yikai Shao, Ruth Gutierrez-Aguilar, Ziru Li, Kristy M. Heppner, Samuel Chiang, Sara G. Vargo, Katrina Granger, Darleen A. Sandoval, Ormond A. MacDougald, Randy J. Seeley
Summary: Intestinal FGF15 plays a crucial role in weight control, bone protection, and glucose tolerance after vertical sleeve gastrectomy (VSG). Knockout of FGF15 in mice leads to more adverse effects during VSG, indicating the importance of FGF15 in post-surgery outcomes.
NATURE COMMUNICATIONS
(2021)
Article
Surgery
Katarzyna Bartosiak, Michal R. Janik, Piotr Kowalewski, Maciej Waledziak, Andrzej Kwiatkowski
Summary: The study aimed to evaluate whether patients regret their decision to undergo laparoscopic sleeve gastrectomy (SG) 5 years after surgery, and to identify the correlation between weight loss, higher quality of life (QoL) scores, and regret. The results suggest that, in general, patients did not regret their decision to undergo SG.
Article
Surgery
P. Hauters, J. -W. Dubart, J. Desmet, R. Degolla, M. Roumain, P. Malvaux
Summary: More than 80% of patients completed a 10-year follow-up, with a success rate of 41% after SG and an incidence of long-term GERD of 65%. Patients with lower preoperative BMI and without preoperative GERD symptoms had a higher success rate with SG.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Multidisciplinary Sciences
Chang Ho Ahn, Eun Hye Choi, Hyunjung Lee, Woochan Lee, Jong-Il Kim, Young Min Cho
Summary: VSG surgery can reduce body weight, improve glucose tolerance, and induce unique gene expression changes in the liver, fat, and muscle, but not more significantly than the pair-fed group of sham-operated mice. VSG surgery can induce organ-specific gene expression changes in the liver, fat, and muscle, which may play critical roles in metabolic improvements after VSG.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, Research & Experimental
Ki-Suk Kim, Bailey Ce Peck, Yu-Han Hung, Kieran Koch-Laskowski, Landon Wood, Priya H. Dedhia, Jason R. Spence, Randy J. Seeley, Praveen Sethupathy, Darleen A. Sandoval
Summary: This study found that vertical sleeve gastrectomy (VSG) increases the number of hormone-secreting enteroendocrine cells (EECs) in the intestine through bile acid signaling, which drives intestinal stem cell fate towards EEC differentiation.
Article
Medicine, General & Internal
Karen J. Coleman, Anirban Basu, Lee J. Barton, Heidi Fischer, David E. Arterburn, Douglas Barthold, Anita Courcoulas, Cecelia L. Crawford, Benjamin B. Kim, Peter N. Fedorka, Edward C. Mun, Sameer B. Murali, Kristi Reynolds, Robert E. Zane, Sami Alskaf
Summary: This study compared the effectiveness of vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB) in the long-term management of dyslipidemia, revealing that RYGB had higher remission rates after 4 years but required close monitoring to prevent relapse.
Article
Multidisciplinary Sciences
Julia L. Nugent, Amar Singh, Keith M. Wirth, Scott Hunter Oppler, Laura Hocum Stone, Jody L. Janecek, Adam C. Sheka, Scott Kizy, Meghan E. G. Moore, Christopher Staley, Bernhard J. Hering, Sabarinathan Ramachandran, Sayeed Ikramuddin, Melanie L. Graham
Summary: The study established a translational nonhuman primate model of vertical sleeve gastrectomy (VSG) that mimics the complexity and outcomes seen in humans, demonstrating that VSG confers durable metabolic benefits and weight loss. Additionally, VSG was shown to be associated with early, weight-independent increases in bile acids, short-chain fatty acids, and a reduction in visceral adipose tissue inflammation.
Article
Endocrinology & Metabolism
Laya Rajan, Cameron C. McKay, Gabriel Santos Malave, Alaina L. Pearce, J. Bradley C. Cherry, Eleanor Mackey, Evan P. Nadler, Chandan J. Vaidya
Summary: Neurocognitive differences in pediatric obesity may be related to cortical structural alterations. Following vertical sleeve gastrectomy (VSG), adolescents with severe obesity showed changes in cortical thickness in certain brain regions, suggesting surgery may lead to structural adjustments in the brain.
Article
Surgery
Juan S. Barajas-Gamboa, Soon Moon, Gustavo Romero-Velez, Andrew T. Strong, Matthew Allemang, Salvador Navarrete, Ricard Corcelles, John Rodriguez, Matthew Kroh, Jerry T. Dang
Summary: This study compared the 30-day rate of serious complications and mortality between primary single anastomosis duodeno-ileal bypass (p-SADI-S) and sleeve gastrectomy (SG) to SADI conversions (SG-SADI). The results showed that SG-SADI conversions had a lower mean body mass index (BMI) at the time of surgery and longer operative times compared to p-SADI-S. However, there was no significant difference in the rate of serious complications between the two groups.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Surgery
Juan S. Barajas-Gamboa, Soon Moon, Gustavo Romero-Velez, Andrew T. Strong, Matthew Allemang, Salvador Navarrete, Ricard Corcelles, John Rodriguez, Matthew Kroh, Jerry T. Dang
Summary: This study compared the 30-day rates of serious complications and mortality between primary SADI-S and conversions from SG to SADI. The results showed that there were similar rates of complications and mortality between SG-SADI and p-SADI-S, indicating that conversion from SG to SADI is safe.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Surgery
David E. Arterburn, Eric Johnson, Karen J. Coleman, Lisa J. Herrinton, Anita P. Courcoulas, David Fisher, Robert A. Li, Mary Kay Theis, Liyan Liu, James R. Fraser, Sebastien Haneuse
Summary: Among patients with severe obesity undergoing SG and RYGB, significantly more weight loss was observed at 5 years compared to nonsurgical patients. Weight regain was common after surgery, but regain to within 5% of baseline was rare.
Article
Gastroenterology & Hepatology
Gontrand Lopez-Nava, Ravishankar Asokkumar, Inmaculada Bautista-Castano, Janese Laster, Anuradha Negi, Stephanie Fook-Chong, Javier Nebreda Duran, Eduard Espinett Coll, Jordi Pujol Gebelli, Amador Garcia Ruiz de Gordejuela
Summary: The study compared the efficacy and safety of endoscopic sleeve gastroplasty (ESG) with laparoscopic sleeve gastrectomy (LSG) and laparoscopic greater curve plication (LGCP) over 2 years. Results showed that although ESG had a slightly lower weight loss rate compared to other techniques, it displayed better safety profile and shorter hospital stay.
Article
Gastroenterology & Hepatology
Emma Rose McGlone, Matthieu Siebert, Marian Dore, David C. D. Hope, Iona Davies, Bryn Owen, Bernard Khoo, Rob Goldin, Dave Carling, Stephen Bloom, Maude Le Gall, Tricia M-M. Tan
Summary: The study investigated the effects of sleeve gastrectomy on weight-independent improvements in liver steatosis in mice with diet-induced obesity. It was found that VSG not only improves liver fat content but also enhances insulin and glucagon sensitivity.
LIVER INTERNATIONAL
(2023)
Article
Respiratory System
Emma Satrell, Hege Clemm, Ola Drange Roksund, Karl Ove Hufthammer, Einar Thorsen, Thomas Halvorsen, Maria Vollsaeter
Summary: Pulmonary diffusing capacity in extremely preterm (EP) infants compared to term-born subjects remains reduced during adulthood, with development tracking in parallel to controls, showing no signs of catch-up growth or decline at age 25 years.
EUROPEAN RESPIRATORY JOURNAL
(2022)
Article
Endocrinology & Metabolism
Hans Jorgen Nielsen, Bjorn Gunnar Nedrebo, Alexander Fossa, John Roger Andersen, Jorg Assmus, Vigdis Halvorsen Dagsland, Simon Nitter Dankel, Oddrun Anita Gudbrandsen, Johan Ferno, Iren Hjellestad, Marianne Jensen Hjermstad, Ronette L. Kolotkin, Havard Luong Thorsen, Gunnar Mellgren, Tone Nygaard Flolo
Summary: This study compared the long-term outcomes of sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) for severe obesity, showing that RYGB resulted in higher weight loss and remission rates of main obesity-related comorbidities, while SG had fewer major early complications.
INTERNATIONAL JOURNAL OF OBESITY
(2022)
Article
Respiratory System
Tonje Bardsen, Ola Drange Roksund, Merete Roineland Benestad, Karl Ove Hufthammer, Hege Havstad Clemm, Ingvild Bruun Mikalsen, Knut Oymar, Trond Markestad, Thomas Halvorsen, Maria Vollsaeter
Summary: The study found that individuals born extremely preterm had significantly lower lung function trajectories from 10 to 35 years compared to those born at term, especially during the period of decline from 25 to 35 years. However, the deficits between extremely preterm-born and term-born individuals decreased with each decade of birth from 1980 to 2000.
Article
Microbiology
Hans Johan Breidablik, Lene Johannessen, John Roger Andersen, Hilde Soreide, Ole T. T. Kleiven
Summary: Efficient hand hygiene is crucial for preventing microbial transmission. Alcohol-based hand rub is recommended, but a water-based hand rub procedure was also investigated. The study compared 27 nurse students and 26 random adults, and found that the ABHR method was more effective at reducing colony forming units than the WBHR method.
Article
Nursing
Kirsten Lerum Indrebo, Anny Aasprang, Torill Elin Olsen, John Roger Andersen
Summary: This study aimed to explore the associations between sociodemographic and clinical data, patient's knowledge and skills, relationship to healthcare professionals, and leakage from an ostomy. The most important risk factors for leakage were found to be non-adherence to international guidelines for ostomy placement, poor relationship with healthcare professionals, non-cancerous diagnosis, lack of knowledge and skills in ostomy care, use of convex baseplate, oval ostomy, and dependence on others for ostomy care. The independent variables in the model explained 31% of the variance in leakage.
Article
Respiratory System
Praveen Muralitharan, Petter Carlsen, Magnus Hilland, Irisz Delestre-Levai, Maria Vollsaeter, Karl Ove Hufthammer, Mette Engan, Ola Drange Roksund, Thomas Halvorsen, Hege H. Clemm
Summary: This study investigated the effects of inhaled ipratropium bromide on exercise-induced laryngeal obstruction (EILO). The results showed that inhaled ipratropium bromide did not improve symptoms or exercise capacity in subjects with EILO. Therefore, this study does not support the use of inhaled ipratropium bromide to treat EILO.
Article
Public, Environmental & Occupational Health
Hans Johan Breidablik, Karl Ove Hufthammer, Vegar Rangul, Jon Roger Andersen, Eivind Meland, Oystein Hetlevik, Tina Lokke Vie
Summary: The study aimed to examine the association between different patterns of physical activity over 36 years and all-cause and cause-specific mortality. It also investigated if this association varied by gender and body mass levels, and how changes in physical activity were related to mortality for individuals who were initially physically inactive. The results showed that engaging in at least 60 minutes of physical activity per week was associated with a significant reduction in mortality, emphasizing the importance of promoting all levels of physical activity in public health campaigns.
SCANDINAVIAN JOURNAL OF PUBLIC HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Tina L. Vie, Karl O. Hufthammer, Vegar Rangul, Jon R. Andersen, Eivind Meland, Hans J. Breidablik
Summary: This study examined physical activity patterns over 34 years in a representative adult population in Norway. The results showed a significant increase in the proportion of adults engaging in 1 hour or more of physical activity per week during the study period. Relatively stable patterns of physical activity were identified, with some variations according to age, gender, and BMI.
SCANDINAVIAN JOURNAL OF PUBLIC HEALTH
(2023)
Article
Medicine, General & Internal
Ase Johnsen Rogde, Sverre Lehmann, Thomas Halvorsen, Hege Havstad Clemm, Ola Drange Roksund, Karl Ove Hufthammer, Haakon Kristian Kvidaland, Maria Vollsaeter, Tiina Maarit Andersen
Summary: The primary aim of this study is to investigate the prevalence of exercise-induced laryngeal obstruction (EILO) in patients with asthma, and also evaluate the treatment effects and comorbid conditions of EILO in these patients. The study will be conducted at Haukeland University Hospital and Voss Hospital in Western Norway, and will include 80-120 patients with asthma and a control group of 40 patients without asthma. Laryngeal function will be assessed using continuous laryngoscopy during high-intensity exercise (CLE), and patients diagnosed with EILO will be treated with standardized breathing advice.
Article
Endocrinology & Metabolism
Ronette L. Kolotkin, Ole Kleist Jeppesen, James Baker-Knight, Sang Yeoup Lee, Asako Tokita, Takashi Kadowaki
Summary: The study examined the impact of semaglutide 2.4 and 1.7 mg versus placebo on weight-related quality of life (WRQOL) and health-related quality of life (HRQOL) in individuals from East Asia. The results showed that semaglutide 2.4 mg significantly improved WRQOL and HRQOL scores, particularly in the psycho-social and physical domains. However, semaglutide 1.7 mg did not show significant effects on HRQOL.
Article
Health Care Sciences & Services
Kirsten Lerum Indrebo, Anny Aasprang, Torill Elin Olsen, John Roger Andersen
Summary: Studies show that patients struggle with adjustment to the ostomy in a broad spectrum of physical and psychosocial factors, and stoma care nurse follow-up is necessary. The study aimed to explore patient satisfaction and experiences using digital questionnaires before each consultation in stoma care nurse ostomy follow-up and to study adjustment to ostomy and health-related quality of life in routine follow-up 3,6 and 12 months after ostomy surgery. The results showed that the patients were satisfied with their follow-up using questionnaires before consultations and experienced improvements in daily activities, knowledge and skills, health, and health-related quality of life.
JOURNAL OF PATIENT-REPORTED OUTCOMES
(2023)
Article
Health Care Sciences & Services
Pal Andre Hegland, Ronette L. Kolotkin, John Roger Andersen
Summary: The study aims to explore the sensitivity of the Patient-Reported Outcomes in Obesity (PROS) to changes in patients undergoing bariatric surgery. The results show that PROS is highly sensitive to time changes and can be used as a simple and easy-to-administer tool for discussing obesity-specific quality of life in clinical consultations.
PATIENT-RELATED OUTCOME MEASURES
(2023)
Article
Health Care Sciences & Services
Heidi Synnove Brevik, Karl Ove Hufthammer, Merete Eide Hernes, Rune Bjorneklett, Guttorm Brattebo
Summary: This article describes the lessons learned during the implementation of the South African Triage Scale Norway (SATS-N) in ambulance services and emergency departments in a health region in Norway. The importance of following a structured framework for quality improvement and securing participation and teamwork across all levels was highlighted.
Article
Psychology, Multidisciplinary
Gry Anette Saelid, Nikolai Olavi Czajkowski, Leif Edvard Aaro, John Roger Andersen, Thormod Idsoe, Miguel Delgado Helleseter, Arne Holte
Summary: The study aimed to evaluate the effects of the MindPower program on symptoms of depression and anxiety among Norwegian high school students. The results showed some baseline differences between the intervention group and the control group. After implementing the MindPower program, there was a slight improvement in depression and anxiety symptoms among both boys and girls. However, the study did not find overall effects of the intervention.
