Review
Nutrition & Dietetics
John K. DiBaise, James S. Scolapio
Summary: This article highlights the importance of home parenteral and enteral nutrition in clinical nutrition and the development of these therapies to support patients. It emphasizes the need for healthcare providers to understand all aspects of HPEN in order to provide safe, effective, and cost-effective support to patients.
Article
Critical Care Medicine
Joanna C. Dionne, Lawrence Mbuagbaw, John W. Devlin, Matthew S. Duprey, Rodrigo Cartin-Ceba, Jennifer Tsang, Kristen Sullivan, John Muscedere, Mohammed Alshahrani, Wojciech Szczeklik, Paul Lysecki, Alyson Takaoka, Brenda Reeve, Tracy Campbell, Karolina Borowska, Wojciech Serednicki, Robert Cirone, Waleed Alhazzani, Paul Moayyedi, David Armstrong, Lehana Thabane, Roman Jaeschke, Cindy Hamielec, Tim Karachi, Deborah J. Cook
Summary: The study revealed a high incidence of diarrhea in ICU patients, with 73.8% affected. Independent predictors of diarrhea included enteral nutrition, antibiotic usage, and suppositories. Diarrhea may prompt changes in patient care.
INTENSIVE CARE MEDICINE
(2022)
Article
Neurosciences
Xiaomin Li, Yafeng Yang, Zheng Feei Ma, Shan Gao, Yuan Ning, Ling Zhao, Zhangya He, Xiaoqin Luo
Summary: Enteral nutrition combined with parenteral nutrition intervention has a positive effect on the clinical prognosis of patients with traumatic brain injury (TBI), reducing the risk of lung infection and improving long-term quality of life score.
NUTRITIONAL NEUROSCIENCE
(2022)
Article
Nutrition & Dietetics
Erin E. Morris, Neely C. Miller, Nicholas A. Marka, Jennifer L. Super, Emily M. Nagel, Juan David Gonzalez, Ellen W. Demerath, Sara E. Ramel
Summary: Retrospective studies show that parenteral nutrition during the first week after birth, providing calories, proteins, and lipids, is associated with improved neurodevelopment. However, an enhanced parenteral nutrition protocol in the early stage did not lead to improved neurodevelopmental outcomes. Instead, higher enteral caloric and protein intake in the first week after birth were associated with improved processing speed.
Article
Nutrition & Dietetics
Juan Carlos Lopez-Delgado, Teodoro Grau-Carmona, Esther Mor-Marco, Maria Luisa Bordeje-Laguna, Esther Portugal-Rodriguez, Carol Lorencio-Cardenas, Paula Vera-Artazcoz, Laura Macaya-Redin, Beatriz Llorente-Ruiz, Rayden Iglesias-Rodriguez, Diana Monge-Donaire, Juan Francisco Martinez-Carmona, Laura Sanchez-Ales, Angel Sanchez-Miralles, Monica Crespo-Gomez, Cristina Leon-Cinto, Jose Luis Flordelis-Lasierra, Lluis Servia-Goixart
Summary: This study evaluated the use, complications, and nutrition delivery associated with parenteral nutrition (PN) in adult critically ill patients, especially when used early and as the initial route. The results showed that early PN administration was safe and provided adequate nutrition delivery. Additional enteral nutrition (EN), when possible, may optimize protein requirements for patients who received initial PN.
Article
Critical Care Medicine
Lee-Anne S. Chapple, Imre W. K. Kouw, Matthew J. Summers, Luke M. Weinel, Samuel Gluck, Eamon Raith, Peter Slobodian, Stijn Soenen, Adam M. Deane, Luc J. C. van Loon, Marianne J. Chapman
Summary: The ability of critically ill patients to synthesize muscle protein from ingested protein is significantly reduced, despite relatively normal protein digestion and amino acid absorption.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2022)
Article
Nutrition & Dietetics
Igor Eckert, Magali C. C. Kumbier, Flavia M. Silva, Oellen S. Franzosi, Jussara C. de Almeida
Summary: The study found that glycemic-control formulae were associated with better blood sugar control and lower insulin requirements in critically ill patients, but the results for clinical outcomes were not statistically significant. There was insufficient evidence to confirm important differences due to low quality of evidence.
CLINICAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Henry P. L. Parkman, Amanda L. Blackford, Helen Burton P. Murray, Katherine P. Yates, Madhusudan Grover, Zubair Malik, Ron S. Schey, Robert S. L. Bulat, Kenneth L. Koch, Irene Sarosiek, Braden J. Kuo, Robert J. P. Shulman, Bruno P. Chumpitazi, Gianrico Farrugia, Laura Miriel, James Tonascia, Frank J. Hamilton, Pankaj J. W. Pasricha, Richard W. L. McCallum, Thomas L. Abell
Summary: This study investigated the frequency of enteral nutrition (EN) and exclusive parenteral nutrition (PN) use in patients with gastroparesis (Gp) and compared them with patients using oral nutrition (ON). The results showed that patients using exclusive PN and/or EN were younger, had lower body mass index, and had greater symptom severity. They also had lower physical quality of life but stable mental quality of life and Gp-related quality of life scores. At the 48-week follow-up, 50% and 25% of patients using exclusive PN and/or EN resumed ON, respectively.
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
(2023)
Article
Nutrition & Dietetics
Jun-Kwon Cha, Hyung-Sook Kim, Eun-Ji Kim, Eun-Sook Lee, Jae-Ho Lee, In-Ae Song
Summary: The initial nutritional delivery policy and route of nutrition delivery may have an impact on the clinical outcomes of patients with sepsis. Higher protein intake during the first week of sepsis onset is associated with lower in-hospital mortality, while higher energy intake is associated with lower 30-day mortality. Additionally, in patients with a high modified nutrition risk in the critically ill score, enteral feeding with supplemental parenteral nutrition is superior to other routes of nutrition delivery and is associated with lower mortality.
Review
Critical Care Medicine
Paul E. Wischmeyer, Danielle E. Bear, Mette M. Berger, Elisabeth De Waele, Jan Gunst, Stephen A. Mcclave, Carla M. Prado, Zudin Puthucheary, Emma J. Ridley, Greet Van den Berghe, Arthur R. H. van Zanten
Summary: Personalization of ICU nutrition is important for the future of critical care. Guidelines recommend low-dose enteral or parenteral nutrition within 48 hours of admission, with consideration for alternative routes when necessary. Indirect calorimetry should be used to measure energy expenditure, and protein delivery should be adjusted based on patient stability. Micronutrient evaluation and muscle monitoring are also important considerations in post-ICU nutrition. Further research is needed on specialized anabolic nutrients and rehabilitation interventions for post-ICU recovery.
Review
Critical Care Medicine
Roland N. Dickerson, Laura Andromalos, J. Christian Brown, Maria Isabel T. D. Correia, Wanda Pritts, Emma J. Ridley, Katie N. Robinson, Martin D. Rosenthal, Arthur R. H. van Zanten
Summary: This review focuses on the best practices in malnutrition screening and assessment, estimation of energy needs, risks and management of sarcopenic obesity, tailored nutrition recommendations, and role of immunonutrition in critically ill patients with obesity. Knowledge gaps persist in managing the complex nutritional needs of these patients. Education efforts and research on current guidelines and evidence are needed to optimize nutrition strategies.
Article
Medicine, General & Internal
Bin Yu, Jiting Wang
Summary: This study conducted a Bayesian network meta-analysis to evaluate the effectiveness of different nutritional interventions for patients with liver cirrhosis, and found that EN + intestinal probiotics appeared to be the most effective strategy.
Review
Nutrition & Dietetics
Aileen Hill, Daren K. Heyland, Luis A. Ortiz Reyes, Elena Laaf, Sebastian Wendt, Gunnar Elke, Christian Stoppe
Summary: This meta-analysis examined the effectiveness of combining enteral nutrition (EN) with parenteral nutrition (PN) in adult patients with acute critical illness, showing that while the combination increased macronutrient delivery, it did not significantly impact patient outcomes compared to EN alone. Larger studies are needed to determine the clinical relevance of this nutrition strategy.
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Claire Dupuis, Alexandre Bret, Alexandra Janer, Olivia Guido, Radhia Bouzgarrou, Loic Dopeux, Gilles Hernandez, Olivier Mascle, Laure Calvet, Francois Thouy, Kevin Grapin, Pierre Couhault, Francis Kinda, Guillaume Laurichesse, Benjamin Bonnet, Mireille Adda, Yves Boirie, Bertrand Souweine
Summary: The study aimed to evaluate the determinants and association between nitrogen balance trajectories and outcome in critically ill COVID-19 patients. The catabolic phase was found to be prolonged in non-survivors compared to survivors. Monitoring urinary nitrogen excretion to guide protein intake is important for COVID-19 patients.
CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Christopher T. Buckley, Nivedita Prasanna, Abby L. Mays, Jeanette M. Tinsley, Roland N. Dickerson
Summary: This study evaluated nitrogen accretion response to varying protein intakes in critically ill ventilator-dependent patients with COVID-19. The results showed significant variability in nitrogen accretion response to protein intake, with a majority of patients experiencing negative nitrogen balance, but some achieving nitrogen equilibrium.
NUTRITION IN CLINICAL PRACTICE
(2021)
Article
Nutrition & Dietetics
Whitney L. Holmes, George O. Maish, Gayle Minard, Martin A. Croce, Roland N. Dickerson
NUTRITION IN CLINICAL PRACTICE
(2020)
Article
Nutrition & Dietetics
Christopher T. Buckley, Edward T. Van Matre, Peter E. Fischer, Gayle Minard, Roland N. Dickerson
Summary: The study evaluated a strategy of using liquid protein supplement boluses, high protein-containing enteral nutrition formulas, and reducing formula rates in traumatic brain injury patients to improve protein delivery while avoiding caloric overfeeding.
NUTRITION IN CLINICAL PRACTICE
(2021)
Review
Nutrition & Dietetics
Roland N. Dickerson
NUTRITION IN CLINICAL PRACTICE
(2020)
Review
Nutrition & Dietetics
Jeffrey I. Mechanick, Salvatore Carbone, Roland N. Dickerson, Beverly J. D. Hernandez, Ryan T. Hurt, Sharon Y. Irving, Ding-You Li, Mary S. McCarthy, Kris M. Mogensen, Juan B. Ochoa Gautier, Jayshil J. Patel, T. Elaine Prewitt, Martin Rosenthal, Malissa Warren, Marion F. Winkler, Liam McKeever
Summary: The purpose of this scoping review by ASPEN's Nutrition Task Force was to examine nutrition research relevant to the COVID-19 pandemic and identify critical areas for urgent research, particularly utilizing RCT design, to enhance nutrition care for patients before, during, and after COVID-19.
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Roland N. Dickerson, Christin N. Crawford, Melissa K. Tsiu, Cara E. Bujanowski, Edward T. Van Matre, Joseph M. Swanson, Dina M. Filiberto, Gayle Minard
Summary: This study aimed to determine the prevalence of augmented renal clearance (ARC) in trauma patients receiving nutrition therapy. Results showed that 50% of patients exhibited ARC, with factors such as male gender, traumatic brain injury, higher injury severity score, younger age, lower serum creatinine concentration, and protein intake being associated with ARC. Patients with multiple risk factors for ARC should be closely monitored for renal dosing of electrolytes, nutrients, and medications.
Article
Nutrition & Dietetics
Christopher T. Buckley, Nivedita Prasanna, Abby L. Mays, Jeanette M. Tinsley, Roland N. Dickerson
Summary: This study evaluated nitrogen accretion response to varying protein intakes in critically ill ventilator-dependent patients with COVID-19. The results showed significant variability in nitrogen accretion response to protein intake, with a majority of patients experiencing negative nitrogen balance, but some achieving nitrogen equilibrium.
NUTRITION IN CLINICAL PRACTICE
(2021)
Article
Pharmacology & Pharmacy
Roland N. Dickerson, Angela L. Bingham, Todd W. Canada, Lingtak Neander Chan, M. Petrea Cober, Sarah V. Cogle, Anne M. Tucker, Vanessa J. Kump
Summary: This article aims to assist pharmacists engaged in nutrition support therapy to stay updated with important literature. Clinical pharmacists compiled a list of articles published in 2020, with a focus on assessing their importance to practice. A total of 169 articles were identified, with 5 primary literature articles and 17 guidelines or consensus papers deemed as high importance.
Review
Pharmacology & Pharmacy
Roland N. Dickerson, Christopher T. Buckley
Summary: Propofol, commonly used sedative in the ICU, is formulated in a 10% lipid emulsion providing 1.1 kcals per mL. However, its high caloric content can lead to potential overfeeding in patients. Clinicians should strive to balance caloric and protein intake to avoid overfeeding complications.
Article
Nutrition & Dietetics
Roland N. Dickerson, Stephen C. Turner, Whitney L. Holmes, Edward T. Van Matre, Joseph M. Swanson, Saskya Byerly, Dina M. Filiberto, Peter E. Fischer
Summary: The study aimed to evaluate the effectiveness of cholecalciferol therapy in reducing hypercalcemia in critically ill vitamin D-deficient patients with traumatic injuries. The findings showed that adjusting the target 25-OH vit D concentration to a lower level significantly reduced the incidence of hypercalcemia and improved the safety of the therapy.
Article
Pharmacology & Pharmacy
Roland N. Dickerson, Angela L. Bingham, Todd W. Canada, Lingtak Neander Chan, M. Petrea Cober, Sarah Cogle, Anne M. Tucker, Vanessa J. Kumpf
Summary: The purpose of this article is to assist pharmacists in nutrition support therapy in staying up to date with relevant literature. A list of important articles from 2021 was compiled and assessed by clinical pharmacists. The top-ranked articles were summarized and their implications to pharmacy nutrition support practice were discussed. It is recommended that pharmacists be familiar with these articles as they are important to their practice.
Article
Nutrition & Dietetics
Roland N. Dickerson, Catherine E. Corley, Whitney L. Holmes, Saskya Byerly, Dina M. Filiberto, Peter E. Fischer
Summary: This study aimed to evaluate the tolerance of gastric feeding in critically ill patients receiving sustained neuromuscular blocker (NMB) pharmacotherapy. The findings showed that most patients tolerated intragastric enteral nutrition during NMB pharmacotherapy, indicating that NMB pharmacotherapy is not an absolute contraindication for gastric feeding.
NUTRITION IN CLINICAL PRACTICE
(2023)
Letter
Nutrition & Dietetics
Roland N. Dickerson
NUTRITION IN CLINICAL PRACTICE
(2023)
Article
Pharmacology & Pharmacy
Roland N. Dickerson, Angela L. Bingham, Todd W. Canada, Lingtak Neander Chan, M. Petrea Cober, Sarah V. Cogle, Anne M. Tucker, Vanessa J. Kumpf
Summary: The purpose of this article is to assist pharmacists engaged in nutrition support therapy in keeping up with relevant literature. A list of important articles published in 2022 was compiled by clinical pharmacists. The authors assessed the importance of each article and identified the ones considered important by at least 5 out of 8 participants. A total of 162 articles were identified, with 8 primary literature articles ranked as highly important. Additionally, 10 guideline and consensus papers were included.
Review
Nutrition & Dietetics
Roland N. Dickerson, Julie E. Farrar, Saskya Byerly, Dina M. Filiberto
Summary: A common misperception is that critically ill patients who receive neuromuscular blocker pharmacotherapy (NMB) cannot tolerate enteral nutrition. This review examines the evidence regarding enteral feeding tolerance for critically ill patients given NMB. Limited evidence suggests that enteral feeding intolerance during NMB is more likely due to underlying illnesses and concurrent opioid analgesia, sedation, and vasopressor therapies. Most critically ill patients can be successfully fed during NMB, and prokinetic pharmacotherapy may be needed in some cases.
NUTRITION IN CLINICAL PRACTICE
(2023)
Article
Pharmacology & Pharmacy
Roland N. Dickerson, Angela L. Bingham, Todd W. Canada, Lingtak N. Chan, M. Petrea Cober, Sarah Cogle, Anne M. Tucker, Vanessa J. Kumpf
