Article
Critical Care Medicine
Tuo Pan, Chen-Yu Jiang, He Zhang, Xi-Kun Han, Hai-Tao Zhang, Xin-Yi Jiang, Wei Chen, Kuo Wang, Fu-Dong Fan, Jun Pan, Qing Zhou, Chuang-Shi Wang, Li Zhang, Dong-Jin Wang
Summary: This study evaluated the myocardial protective effect of colchicine in patients undergoing non-CABG cardiac surgery. The results showed that colchicine significantly reduced postoperative cardiac injury and inflammation, and decreased the occurrence of postoperative syndrome.
Letter
Medicine, General & Internal
Felix Hennig, Christoph Knosalla
Summary: Devereaux et al. have contributed to the characterization of appropriate thresholds for defining myocardial damage after cardiac surgery, particularly in relation to the use of different cardioplegic solutions.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Mahmoud Diab, Thomas Lehmann, Wolfgang Bothe, Payam Akhyari, Stephanie Platzer, Daniel Wendt, Antje-Christin Deppe, Justus Strauch, Stefan Hagel, Albrecht Guenther, Gloria Faerber, Christoph Sponholz, Marcus Franz, Andre Scherag, Ilia Velichkov, Miriam Silaschi, Jens Fassl, Britt Hofmann, Sven Lehmann, Rene Schramm, Georg Fritz, Gabor Szabo, Thorsten Wahlers, Klaus Matschke, Artur Lichtenberg, Mathias W. Pletz, Jan F. Gummert, Friedhelm Beyersdorf, Christian Hagl, Michael A. Borger, Michael Bauer, Frank M. Brunkhorst, Torsten Doenst
Summary: This study investigated the effect of hemoadsorption during cardiac surgery for infective endocarditis (IE) on postoperative organ dysfunction and found that hemoadsorption did not reduce the occurrence of organ dysfunction. Although hemoadsorption reduced cytokine levels during surgery, it did not have an impact on clinically relevant outcome measures.
Review
Biochemistry & Molecular Biology
Giuseppe Filiberto Serraino, Federica Jiritano, Davide Costa, Nicola Ielapi, Domenica Battaglia, Umberto Marcello Bracale, Pasquale Mastroroberto, Michele Andreucci, Raffaele Serra
Summary: This systematic review aims to explore the role of matrix metalloproteinases (MMPs) in routine cardiac operations, especially cardiopulmonary bypass (CPB). The results show that MMP levels are significantly correlated with CPB and the gelatinases MMP-2 and MMP-9 are highly released during cardiac surgery with CPB. Increased MMP levels are associated with adverse post-operative outcomes. Future large-scale prospective multicenter randomized clinical trials are needed to investigate the impact of mechanical and pharmacological strategies on the inflammatory response and postoperative outcomes in cardiac surgery and CPB.
Review
Health Care Sciences & Services
Luan Oliveira Ferreira, Victoria Winkler Vasconcelos, Janielle de Sousa Lima, Jaime Rodrigues Vieira Neto, Giovana Escribano da Costa, Jordana de Castro Esteves, Sallatiel Cabral de Sousa, Jonathan Almeida Moura, Felipe Ruda Silva Santos, Joao Monteiro Leitao Filho, Matheus Ramos Protasio, Pollyana Sousa Araujo, Claudio Jose da Silva Lemos, Karina Dias Resende, Dielly Catrina Favacho Lopes
Summary: Patients undergoing coronary revascularization with extracorporeal circulation or cardiopulmonary bypass may develop systemic inflammatory response due to biochemical changes in the microcirculation. Inflammatory signaling pathways can be activated by surgical incision, reperfusion injury, and blood contact with non-endothelial membranes, leading to the production and activation of inflammatory cells, cytokine production, and oxidative stress. Addressing new perspectives for intraoperative treatment and management may reduce this inflammatory storm, improve prognosis, and potentially lower mortality rates in these patients.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Anesthesiology
John Keong Chiew, Christopher Jer Wei Low, Kieran Zeng, Zhi Jie Goh, Ryan Ruiyang Ling, Ying Chen, Lian Kah Ti, Kollengode Ramanathan
Summary: A systematic review and meta-analysis showed that thoracic epidural anesthesia (TEA) in cardiac surgery is beneficial, reducing intensive care unit (ICU) and hospital length of stay, as well as postoperative complications. The use of TEA also resulted in a significantly shorter extubation time.
ANESTHESIA AND ANALGESIA
(2023)
Review
Medicine, General & Internal
Christina Massoth, Alexander Zarbock
Summary: Acute kidney injury after cardiac surgery presents specific patterns of damage and recovery, which are crucial for management and outcomes. The KDIGO classification only partially covers the conceptual framework and is insufficient for a comprehensive diagnosis. This review discusses the strengths and limitations of recent criteria for CSA-AKI and provides an overview of biomarkers. The evolving understanding of CSA-AKI as a time-sensitive condition has led to an increased demand for enhancing diagnostic criteria and implementing biomarkers in clinical practice.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cell Biology
Paul Philipp Heinisch, Maks Mihalj, Markus Huber, Joerg C. Schefold, Alexander Hartmann, Michael Walter, Elisabeth Steinhagen-Thiessen, Juerg Schmidli, Frank Stueber, Lorenz Raeber, Markus M. Luedi
Summary: This study aimed to investigate the impact of the metabolic product Lp(a) on complications and clinical outcomes in high-risk cardiovascular patients undergoing cardiac surgery. Findings showed a general decrease in Lp(a) levels after all types of cardiac surgery, with elevated Lp(a) levels not being associated with perioperative events or mortality rates.
Article
Cardiac & Cardiovascular Systems
Xinglong Xiong, Dongxu Chen, Shuang Cai, Li Qiu, Jing Shi
Summary: This study found that intraoperative hyperglycemia is associated with an increased risk of postoperative infections in patients undergoing cardiac surgery. The optimal blood glucose level during surgery should be maintained below 150 mg/dL to reduce infection risk.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Annewil van Saet, Gerdien A. Zeilmaker-Roest, Kevin M. Veen, Saskia N. de Wildt, Fritz Sorgel, Robert J. Stolker, Ad J. J. C. Bogers, Dick Tibboel
Summary: The pharmacokinetics and plasma concentrations of methylprednisolone have not been comprehensively studied in children with congenital heart disease undergoing cardiac surgery with cardiopulmonary bypass. There may be a significant influence of cardiopulmonary bypass on the plasma concentrations of methylprednisolone, which could explain the limited efficacy of steroid administration in this context.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Medicine, General & Internal
Chantal A. Boly, Margot Venhuizen, Nicole A. M. Dekker, Alexander B. A. Vonk, Christa Boer, Charissa E. van den Brom
Summary: Cardiac surgery with cardiopulmonary bypass impairs microcirculatory perfusion equally in metabolically healthy obese patients and lean patients, with recovery observed in both groups within three days post-surgery.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Medical Laboratory Technology
Giuseppe Lapergola, Alessandro Graziosi, Ebe D'Adamo, Patrizia Brindisino, Mariangela Ferrari, Anna Romanelli, Mariachiara Strozzi, Roberta Libener, Danilo A. W. Gavilanes, Antonio Maconi, Angela Satriano, Alessandro Varrica, Diego Gazzolo
Summary: Recent advances in perioperative management have significantly reduced mortality rate in open heart surgery and cardiopulmonary bypass for heart disease repair. However, the morbidity rate remains unchanged. The measurement of neuro-biomarkers, particularly S100B protein, can be useful in detecting early stage brain damage during the perioperative period. This review provides an updated overview of the pros and cons of using S100B protein for perioperative monitoring in both adult and pediatric patients.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2022)
Article
Critical Care Medicine
Mathieu Lesouhaitier, Fabrice Uhel, Murielle Gregoire, Arnaud Gacouin, Aurelien Frerou, Baptiste Gaudriot, Claude Bendavid, Sarrah Boukthir, Yves Le Tulzo, Jean-Philippe Verhoye, Erwan Flecher, Mikael Roussel, Karin Tarte, Jean-Marc Tadie
Summary: Cardiac surgery with cardiopulmonary bypass (CPB) leads to immunosuppression, characterized by decreased lymphocyte subsets, expansion of monocytic MDSCs, increased T-cell apoptosis, and decreased proliferation capacity. The activity of indoleamine 2,3-dioxygenase and IL-10 plasma level increase after CPB, while arginine plasma level decreases. Only arginine supplementation partially restores T-cell proliferation.
Article
Cardiac & Cardiovascular Systems
Bogdan A. Kindzelski, Faisal G. Bakaeen, Michael Z. Tong, Eric E. Roselli, Edward G. Soltesz, Douglas R. Johnston, Per Wierup, Gosta B. Pettersson, Penny L. Houghtaling, Eugene H. Blackstone, A. Marc Gillinov, Lars G. Svensson
Summary: This study evaluates the practice and outcomes of reoperative cardiac surgery via re-sternotomy. It finds that reoperative cardiac surgery is associated with low operative morbidity and mortality at an experienced center. The study also suggests that early and late cardiopulmonary bypass strategies have similar outcomes in the context of an image-guided, team-based strategy.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Multidisciplinary Sciences
Parag N. Jain, Matthew Robertson, Javier J. Lasa, Lara Shekerdemian, Danielle Guffey, Yuhao Zhang, Krithika Lingappan, Paul Checchia, Cristian Coarfa
Summary: The study explored differential gene expression profiles in neonates with HLHS who develop LCOS after CPB, revealing significant changes in inflammatory and metabolic pathways. This opens up new possibilities for identifying potential therapeutic targets in this high-risk population.
SCIENTIFIC REPORTS
(2021)
Article
Psychology, Clinical
Gabino Cervantes-Guevara, Manuel Maciel-Saldierna, Emmanuel Elizondo-Hernandez, Lorena Alejandra Cervantes-Perez, Guillermo Alonso Cervantes-Cardona, Bejanmin Garcia-Reyna, Juan Carlos Ibarrola-Pena, Yolanda Lorelei Almanza-Mena, Francisco Jose Barbosa-Camacho, Clotilde Fuentes-Orozco, Jonathan Matias Chejfec-Ciociano, Jose Aldo Guzman-Barba, Paola Flores-Becerril, Emilio Alberto Reyes-Elizalde, Alejandro Gonzalez-Ojeda
INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION
(2022)
Article
Psychology, Clinical
Francisco Jose Barbosa-Camacho, Benjamin Garcia-Reyna, Guillermo Alonso Cervantes-Cardona, Enrique Cervantes-Perez, Efrain Chavarria-Avila, Kevin Josue Pintor-Belmontes, Bertha Georgina Guzman-Ramirez, Aldo Bernal-Hernandez, Juan Carlos Ibarrola-Pena, Clotilde Fuentes-Orozco, Alejandro Gonzalez-Ojeda, Gabino Cervantes-Guevara
Summary: The COVID-19 pandemic and social distancing measures have led to stress, psychological instability, stigmatization, fear, and discrimination worldwide. A survey conducted on hospital staff found significant differences between men and women in their fear levels. Medical students showed higher levels of fear compared to experienced medical personnel, and medical and nursing staff had higher levels of fear compared to non-medical staff who did not work directly with COVID-19 patients. These findings suggest that greater knowledge of medicine or infectious diseases could help mitigate the psychological impact of the pandemic.
INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION
(2023)
Article
Psychology, Multidisciplinary
Benjamin Garcia-Reyna, Gilberto Daniel Castillo-Garcia, Francisco Jose Barbosa-Camacho, Guillermo Alonso Cervantes-Cardona, Enrique Cervantes-Perez, Isaac Esparza-Estrada, Irma Valeria Brancaccio-Perez, Gabriela Silva-Gonzalez, Clotilde Fuentes-Orozco, Kevin Josue Pintor-Belmontes, Bertha Georgina Guzman-Ramirez, Dinorah Rodriguez Navarro, Juan Carlos Ibarrola-Pena, Veronica Alexandra Sanchez Lopez, Jonathan Matias Chejfec-Ciociano, Jose Hector Sapien-Fernandez, Alejandro Gonzalez-Ojeda, Gabino Cervantes-Guevara
Summary: This study found that hospital employees are experiencing anxiety during the COVID-19 pandemic, with non-clinical personnel presenting the highest levels of anxiety. Women scored higher on the Coronavirus Anxiety Scale compared to men.
Article
Surgery
Shadya Betancourt-Vicencio, Manuel Rodrigo Prieto-Aldape, Andrea Socorro Alvarez-Villasenor, Clotilde Fuentes-Orozco, Ana Olivia Cortes-Flores, Guadalupe Castillo-Cardiel, Jose Antonio Sanchez-Martinez, Emilio Alberto Reyes-Elizalde, Paola Guadalupe Gonzalez-Hernandez, Jose Gerardo Zamora-Inzunza, Victoria Amaranta Romero-Arredondo, Jose Francisco Barbosa-Camacho, Irma Valeria Brancaccio-Perez, Bertha Georgina Guzman-Ramirez, Alejandro Gonzalez-Ojeda
Summary: This study evaluated the effects of PFD on anastomosis healing and adhesion genesis in a low-risk rat model of dehiscence of colonic anastomosis. The results showed that the bursting pressure was higher, and the macroscopic adhesions were soft and had less inflammatory infiltration and higher collagen content in the PFD group compared to the control group.
EUROPEAN SURGICAL RESEARCH
(2023)
Article
Environmental Sciences
Juan Carlos Ibarrola-Pena, Tania Abigail Cueto-Valadez, Jonathan Matias Chejfec-Ciociano, Luis Rodrigo Cifuentes-Andrade, Andrea Estefania Cueto-Valadez, Guadalupe Castillo-Cardiel, Guillermo Alonso Cervantes-Cardona, Enrique Cervantes-Perez, Gabino Cervantes-Guevara, Mario Jesus Guzman-Ruvalcaba, Jose Hector Sapien-Fernandez, Jose Aldo Guzman-Barba, Isaac Esparza-Estrada, Paola Flores-Becerril, Irma Valeria Brancaccio-Perez, Bertha Georgina Guzman-Ramirez, Andrea Socorro Alvarez-Villasenor, Francisco Jose Barbosa-Camacho, Emilio Alberto Reyes-Elizalde, Clotilde Fuentes-Orozco, Alejandro Gonzalez-Ojeda
Summary: This observational cross-sectional study examined changes in substance use during the COVID-19 pandemic in Mexico, and whether depression or anxiety was associated with these new consumption patterns. An online survey was distributed to the general population, and results showed that substance use patterns were affected by the pandemic, with an increase in the number of users and consumption rate, as well as reported psychiatric symptoms.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2023)
Article
Medicine, General & Internal
Mariana Chavez-Tostado, Karla Veronica Chavez-Tostado, Gabino Cervantes-Guevara, Guillermo Cervantes-Cardona, Diana Mercedes Hernandez-Corona, Tonatiuh Gonzalez-Heredia, Miriam Mendez-del Villar, Fernanda Isadora Corona-Meraz, Milton Omar Guzman-Ornelas, Francisco Jose Barbosa-Camacho, Andrea Socorro Alvarez-Villasenor, Enrique Cervantes-Perez, Clotilde Fuentes-Orozco, Natalia Guadalupe Barrera-Lopez, Noelia Esthela Lopez-Bernal, Alejandro Gonzalez-Ojeda
Summary: This study aimed to examine the prevalence of breastfeeding practices and postpartum depression among Mexican women during the COVID-19 pandemic. The results suggest that the pandemic has negatively affected the well-being of postpartum women, and encouraging breastfeeding and skin-to-skin contact can improve emotional stability and mental health in this population.
MEDICINA-LITHUANIA
(2023)
Article
Medicine, General & Internal
Francisco J. Hernandez-Mora, Claudia K. Cerda-Guerrero, Leonel Garcia-Benavides, Enrique Cervantes-Perez, Sol Ramirez-Ochoa, Janet Cristina Vazquez-Beltran, Gabino Cervantes-Guevara, Ernesto Ledezma-Hurtado, Adriana Napoles-Echauri, Alejandro Gonzalez-Ojeda, Clotilde Fuentes-Orozco, Maria Isabel Hernandez-Rivas, Mariana Chavez-Tostado, Guillermo A. Cervantes-Cardona
Summary: This study aimed to compare central aortic pressure (CAP) in women with preeclampsia and normotensive postpartum women in an urban region in western Mexico. The results showed that systolic CAP was significantly elevated in women with preeclampsia, which could indicate an increased risk of cardiovascular disease.
MEDICINA-LITHUANIA
(2023)
Article
Medicine, General & Internal
Lorena A. Cervantes-Perez, Gabino Cervantes-Guevara, Enrique Cervantes-Perez, Guillermo Alonso Cervantes-Cardona, Adriana Napoles-Echauri, Alejandro Gonzalez-Ojeda, Clotilde Fuentes-Orozco, Gabino Cervantes-Perez, Carlos A. Reyes-Torres, Francisco Javier Hernandez-Mora, Ana Lucia Ron-Magana, Janet Cristina Vazquez-Beltran, Maria Isabel Hernandez-Rivas, Sol Ramirez-Ochoa
Summary: This study aimed to evaluate the efficacy of a combination therapy of atorvastatin and N-acetyl cysteine in patients with immune thrombocytopenia. The results showed that this combination therapy could significantly increase platelet counts, indicating its potential as a treatment option for patients with primary immune thrombocytopenia.
MEDICINA-LITHUANIA
(2023)
Article
Medicine, General & Internal
Josue I. Ruiz-Gallardo, Enrique Cervantes-Perez, Andrea Perez de Acha-Chavez, Guillermo A. Cervantes-Cardona, Sol Ramirez-Ochoa, Adriana Napoles-Echauri, Alejandro Gonzalez-Ojeda, Clotilde Fuentes-Orozco, Francisco Javier Hernandez-Mora, Eduardo Gomez-Sanchez, Jorge I. I. Michel-Gonzalez, Carlos Miguel Gonzalez-Valencia, Gabino Cervantes-Guevara
Summary: The study aimed to investigate the clinical and biochemical characteristics associated with remission of acute kidney injury (AKI) in Mexican patients. The results showed that the presence of chronic kidney disease, higher serum creatinine levels at admission, lower estimated glomerular filtration rate, higher maximum serum creatinine during hospitalization, higher fractional excretion of sodium and 24-hour urine protein, higher serum potassium levels at admission, abnormal levels of procalcitonin, and increased risk of death were associated with nonremitting AKI. These findings can help identify patients at risk for nonremitting AKI based on clinical and biochemical characteristics, and inform the design of strategies for the surveillance, prevention, and treatment of AKI.
MEDICINA-LITHUANIA
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jaime E. Castellanos-Bermejo, Gabino Cervantes-Guevara, Enrique Cervantes-Perez, Guillermo A. Cervantes-Cardona, Sol Ramirez-Ochoa, Clotilde Fuentes-Orozco, Gonzalo Delgado-Hernandez, Jaime A. Tavares-Ortega, Erika Gomez-Mejia, Jonathan M. Chejfec-Ciociano, Juan A. Flores-Prado, Francisco J. Barbosa-Camacho, Alejandro Gonzalez-Ojeda
Summary: This study compared the diagnostic effectiveness of a single-reviewer approach and a dual-reviewer approach in chest CT diagnosis for patients with pneumonia secondary to SARS-CoV-2. The results showed that the dual-reviewer approach improved the accuracy of chest CT diagnosis compared to the conventional single-reviewer approach.
Article
Psychology, Clinical
Benjamin Garcia-Reyna, Gilberto Daniel Castillo-Garcia, Francisco Jose Barbosa-Camacho, Guillermo Alonso Cervantes-Cardona, Enrique Cervantes-Perez, Blanca Miriam Torres-Mendoza, Clotilde Fuentes-Orozco, Kevin Josue Pintor-Belmontes, Bertha Georgina Guzman-Ramirez, Aldo Hernandez-Bernal, Alejandro Gonzalez-Ojeda, Gabino Cervantes-Guevara
Summary: This study used the Fear of COVID-19 Scale to assess the fear response among health personnel in Mexico and found significantly higher levels of fear in nursing and administrative staff. This research contributes to a better understanding of the psychological impact of COVID-19 on healthcare workers.
INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION
(2022)
