Sustained expression of miR-26a promotes chromosomal instability and tumorigenesis through regulation of CHFR

Overexpression of LARP1 predicts poor prognosis of colorectal cancer and is expected to be a potential therapeutic target

(2016) Ling Ye et al.   TUMOR BIOLOGY

Aneuploidy

(2015) Bernardo Orr et al.   CURRENT BIOLOGY

TP53 regulates miRNA association with AGO2 to remodel the miRNA–mRNA interaction network

(2015) Jonathan Krell et al.   GENOME RESEARCH

SurvMicro: assessment of miRNA-based prognostic signatures for cancer clinical outcomes by multivariate survival analysis

(2014) Raul Aguirre-Gamboa et al.   BIOINFORMATICS

miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts

(2013) Loredana Pellegrino et al.   NUCLEIC ACIDS RESEARCH

miR-16 and miR-26a target checkpoint kinases Wee1 and Chk1 in response to p53 activation by genotoxic stress

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MiR-26a enhances metastasis potential of lung cancer cells via AKT pathway by targeting PTEN

(2012) Boning Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

MicroRNA-26a/b and their host genes cooperate to inhibit the G1/S transition by activating the pRb protein

(2012) Ying Zhu et al.   NUCLEIC ACIDS RESEARCH

Trastuzumab Produces Therapeutic Actions by Upregulating miR-26a and miR-30b in Breast Cancer Cells

(2012) Takehiro Ichikawa et al.   PLoS One

The Auto-ubiquitylation of E3 Ubiquitin-protein Ligase Chfr at G2Phase Is Required for Accumulation of Polo-like Kinase 1 and Mitotic Entry in Mammalian Cells

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miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4–NOT

(2011) Marc R Fabian et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

miRNA repression involves GW182-mediated recruitment of CCR4–NOT through conserved W-containing motifs

(2011) Marina Chekulaeva et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Pathologically decreased miR-26a antagonizes apoptosis and facilitates carcinogenesis by targeting MTDH and EZH2 in breast cancer

(2010) B. Zhang et al.   CARCINOGENESIS

14-3-3 Coordinates Microtubules, Rac, and Myosin II to Control Cell Mechanics and Cytokinesis

(2010) Qiongqiong Zhou et al.   CURRENT BIOLOGY

Aurora B and 14-3-3 Coordinately Regulate Clustering of Centralspindlin during Cytokinesis

(2010) Max E. Douglas et al.   CURRENT BIOLOGY

Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells

(2010) M. Fenech et al.   MUTAGENESIS

Genomic instability — an evolving hallmark of cancer

(2010) Simona Negrini et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The RNA binding protein Larp1 regulates cell division, apoptosis and cell migration

(2010) C. Burrows et al.   NUCLEIC ACIDS RESEARCH

miRTarBase: a database curates experimentally validated microRNA–target interactions

(2010) Sheng-Da Hsu et al.   NUCLEIC ACIDS RESEARCH

Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship

(2010) H. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

(2009) Janaiah Kota et al.   CELL

The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo

(2009) J. T. Huse et al.   GENES & DEVELOPMENT

A mechanism linking extra centrosomes to chromosomal instability

(2009) Neil J. Ganem et al.   NATURE

Multipolar Spindle Pole Coalescence Is a Major Source of Kinetochore Mis-Attachment and Chromosome Mis-Segregation in Cancer Cells

(2009) William T. Silkworth et al.   PLoS One

The estrogen receptor- -induced microRNA signature regulates itself and its transcriptional response

(2009) L. Castellano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MYC stimulates EZH2 expression by repression of its negative regulator miR-26a

(2008) S. Sander et al.   BLOOD

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE