The conserved AU dinucleotide at the 5′ end of nascent U1 snRNA is optimized for the interaction with nuclear cap-binding-complex

Structure of a spliceosome remodelled for exon ligation

(2017) Sebastian M. Fica et al.   NATURE

Cryo-EM structure of a human spliceosome activated for step 2 of splicing

(2017) Karl Bertram et al.   NATURE

Noncanonical registers and base pairs in human 5′ splice-site selection

(2016) Jiazi Tan et al.   NUCLEIC ACIDS RESEARCH

Structure of a yeast step II catalytically activated spliceosome

(2016) Chuangye Yan et al.   SCIENCE

Structure–function analysis and genetic interactions of the Yhc1, SmD3, SmB, and Snp1 subunits of yeast U1 snRNP and genetic interactions of SmD3 with U2 snRNP subunit Lea1

(2015) Beate Schwer et al.   RNA

Two Routes to Genetic Suppression of RNA Trimethylguanosine Cap Deficiency via C-Terminal Truncation of U1 snRNP Subunit Snp1 or Overexpression of RNA Polymerase Subunit Rpo26

(2015) Zhicheng R. Qiu et al.   G3-Genes Genomes Genetics

A day in the life of the spliceosome

(2014) A. Gregory Matera et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structure-function analysis of the Yhc1 subunit of yeast U1 snRNP and genetic interactions of Yhc1 with Mud2, Nam8, Mud1, Tgs1, U1 snRNA, SmD3 and Prp28

(2014) Beate Schwer et al.   NUCLEIC ACIDS RESEARCH

Cap-binding complex (CBC)

(2013) Thomas Gonatopoulos-Pournatzis et al.   BIOCHEMICAL JOURNAL

Functions of the DExD/H-box proteins in nuclear pre-mRNA splicing

(2013) Tien-Hsien Chang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

From Structure to Systems: High-Resolution, Quantitative Genetic Analysis of RNA Polymerase II

(2013) Hannes Braberg et al.   CELL

Pick one, but be quick: 5' splice sites and the problems of too many choices

(2013) X. Roca et al.   GENES & DEVELOPMENT

Structure-function analysis of the 5′ end of yeast U1 snRNA highlights genetic interactions with the Msl5•Mud2 branchpoint-binding complex and other spliceosome assembly factors

(2013) Beate Schwer et al.   NUCLEIC ACIDS RESEARCH

Widespread recognition of 5' splice sites by noncanonical base-pairing to U1 snRNA involving bulged nucleotides

(2012) X. Roca et al.   GENES & DEVELOPMENT

Genetic interactions of hypomorphic mutations in the m7G cap-binding pocket of yeast nuclear cap binding complex: An essential role for Cbc2 in meiosis via splicing of MER3 pre-mRNA

(2012) Z. R. Qiu et al.   RNA

Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1Δ cells

(2011) Beate Schwer et al.   NUCLEIC ACIDS RESEARCH

A Tradeoff Drives the Evolution of Reduced Metal Resistance in Natural Populations of Yeast

(2011) Shang-Lin Chang et al.   PLoS Genetics

ScreenMill: A freely available software suite for growth measurement, analysis and visualization of high-throughput screen data

(2010) John C Dittmar et al.   BMC BIOINFORMATICS

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

A Targeted Bypass Screen Identifies Ynl187p, Prp42p, Snu71p, and Cbp80p for Stable U1 snRNP/Pre-mRNA Interaction

(2009) R. Hage et al.   MOLECULAR AND CELLULAR BIOLOGY

The Evolutionarily Conserved Core Design of the Catalytic Activation Step of the Yeast Spliceosome

(2009) Patrizia Fabrizio et al.   MOLECULAR CELL

Dynamic Regulation of Alternative Splicing by Silencers that Modulate 5′ Splice Site Competition

(2008) Yang Yu et al.   CELL

Genetic and Biochemical Analysis of Yeast and Human Cap Trimethylguanosine Synthase

(2008) Stéphane Hausmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diverse Role of Three Tyrosines in Binding of the RNA 5′ Cap to the Human Nuclear Cap Binding Complex

(2008) Remigiusz Worch et al.   JOURNAL OF MOLECULAR BIOLOGY