XIAP upregulates expression of HIF target genes by targeting HIF1α for Lys63-linked polyubiquitination

Ubiquitin modifications

(2016) Kirby N Swatek et al.   CELL RESEARCH

Ubc13: the Lys63 ubiquitin chain building machine

(2016) Curtis D. Hodge et al.   Oncotarget

Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting

(2015) Curtis D. Hodge et al.   ACS Chemical Biology

Emerging roles of Lys63-linked polyubiquitylation in immune responses

(2015) Xuefeng Wu et al.   IMMUNOLOGICAL REVIEWS

Nuclear-cytoplasmatic shuttling of proteins in control of cellular oxygen sensing

(2015) Reinhard Depping et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

K63 polyubiquitination is a new modulator of the oxidative stress response

(2015) Gustavo M Silva et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

K63 polyubiquitination is a new modulator of the oxidative stress response

(2015) Gustavo M Silva et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

STUB1/CHIP is required for HIF1A degradation by chaperone-mediated autophagy

(2013) João Vasco Ferreira et al.   Autophagy

The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system

(2013) Sam Strickson et al.   BIOCHEMICAL JOURNAL

TRAF6 Upregulates Expression of HIF-1  and Promotes Tumor Angiogenesis

(2013) H. Sun et al.   CANCER RESEARCH

Targeting the Ubiquitin Proteasome System: Beyond Proteasome Inhibition

(2013) Wendy Xolalpa et al.   CURRENT PHARMACEUTICAL DESIGN

Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A

(2012) M. Pulvino et al.   BLOOD

IAP proteins: regulators of cell migration and development

(2012) Niall S Kenneth et al.   CURRENT OPINION IN CELL BIOLOGY

XIAP Monoubiquitylates Groucho/TLE to Promote Canonical Wnt Signaling

(2012) Alison J. Hanson et al.   MOLECULAR CELL

Evolutionary Conserved Regulation of HIF-1β by NF-κB

(2011) Patrick van Uden et al.   PLoS Genetics

A Central Role for Hypoxic Signaling in Cartilage, Bone, and Hematopoiesis

(2011) Erinn B. Rankin et al.   Current Osteoporosis Reports

Hypoxia-inducible factor-1α protein expression is associated with poor survival in normal karyotype adult acute myeloid leukemia

(2010) George Deeb et al.   LEUKEMIA RESEARCH

ATM- and NEMO-Dependent ELKS Ubiquitination Coordinates TAK1-Mediated IKK Activation in Response to Genotoxic Stress

(2010) Zhao-Hui Wu et al.   MOLECULAR CELL

The Role of Ubiquitin in NF-κB Regulatory Pathways

(2009) Brian Skaug et al.   Annual Review of Biochemistry

Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities

(2009) Roland Hjerpe et al.   EMBO REPORTS

Origin and function of ubiquitin-like proteins

(2009) Mark Hochstrasser   NATURE

Regulation of hematopoiesis by the K63-specific ubiquitin-conjugating enzyme Ubc13

(2009) X. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxygen homeostasis

(2009) Gregg L. Semenza   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Regulation of gene expression by hypoxia

(2008) Niall Steven Kenneth et al.   BIOCHEMICAL JOURNAL

Regulation of hypoxia-inducible factor-1α by NF-κB

(2008) Patrick van Uden et al.   BIOCHEMICAL JOURNAL

Atypical ubiquitin chains: new molecular signals. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Fumiyo Ikeda et al.   EMBO REPORTS

Atypical CRM1-dependent Nuclear Export Signal Mediates Regulation of Hypoxia-inducible Factor-1α by MAPK

(2008) Ilias Mylonis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

(2008) Jordi Rius et al.   NATURE

The HIF/VHL Pathway

(2007) Sarah R. Walmsley et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY