Paf1 and Ctr9, core components of the PAF1 complex, maintain low levels of telomeric repeat containing RNA

A practical qPCR approach to detect TERRA, the elusive telomeric repeat-containing RNA

(2017) Marianna Feretzaki et al.   METHODS

Paf1 Has Distinct Roles in Transcription Elongation and Differential Transcript Fate

(2017) Harry Fischl et al.   MOLECULAR CELL

Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex

(2017) Youwei Xu et al.   Nature Communications

TERRA promotes telomerase‐mediated telomere elongation inSchizosaccharomyces pombe

(2016) Martin Moravec et al.   EMBO REPORTS

Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress

(2016) Jérôme Poli et al.   GENES & DEVELOPMENT

PAF Complex Plays Novel Subunit-Specific Roles in Alternative Cleavage and Polyadenylation

(2016) Yan Yang et al.   PLoS Genetics

PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II

(2015) Fei Xavier Chen et al.   CELL

Telomeric Repeat Containing RNA (TERRA): Aging and Cancer

(2015) Sonam Sinha et al.   CNS & Neurological Disorders-Drug Targets

The cellular growth rate controls overall mRNA turnover, and modulates either transcription or degradation rates of particular gene regulons

(2015) José García-Martínez et al.   NUCLEIC ACIDS RESEARCH

NCG 5.0: updates of a manually curated repository of cancer genes and associated properties from cancer mutational screenings

(2015) Omer An et al.   NUCLEIC ACIDS RESEARCH

Telomere functions grounding on TERRA firma

(2015) Claus M. Azzalin et al.   TRENDS IN CELL BIOLOGY

Global Analysis of mRNA Isoform Half-Lives Reveals Stabilizing and Destabilizing Elements in Yeast

(2014) Joseph V. Geisberg et al.   CELL

The molecular topography of silenced chromatin in Saccharomyces cerevisiae

(2014) D. M. Thurtle et al.   GENES & DEVELOPMENT

The differential processing of telomeres in response to increased telomeric transcription and RNA–DNA hybrid accumulation

(2014) Bettina Balk et al.   RNA Biology

RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells

(2014) Rajika Arora et al.   Nature Communications

Interplay between Nonsense-Mediated mRNA Decay and DNA Damage Response Pathways Reveals that Stn1 and Ten1 Are the Key CST Telomere-Cap Components

(2014) Eva-Maria Holstein et al.   Cell Reports

Telomeric Noncoding RNA TERRA Is Induced by Telomere Shortening to Nucleate Telomerase Molecules at Short Telomeres

(2013) Emilio Cusanelli et al.   MOLECULAR CELL

Bimodal expression of PHO84 is modulated by early termination of antisense transcription

(2013) Manuele Castelnuovo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence

(2013) Bettina Balk et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The many roles of the conserved eukaryotic Paf1 complex in regulating transcription, histone modifications, and disease states

(2012) Brett N. Tomson et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α

(2012) Nausica Arnoult et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Deregulated telomere transcription causes replication-dependent telomere shortening and promotes cellular senescence

(2012) André Maicher et al.   NUCLEIC ACIDS RESEARCH

TERRA Promotes Telomere Shortening through Exonuclease 1–Mediated Resection of Chromosome Ends

(2012) Verena Pfeiffer et al.   PLoS Genetics

Telomeres: The silence is broken

(2011) Claus M. Azzalin et al.   CELL CYCLE

Subtelomeric repetitive elements determine TERRA regulation by Rap1/Rif and Rap1/Sir complexes in yeast

(2011) Nahid Iglesias et al.   EMBO REPORTS

SHP2 Tyrosine Phosphatase Converts Parafibromin/Cdc73 from a Tumor Suppressor to an Oncogenic Driver

(2011) Atsushi Takahashi et al.   MOLECULAR CELL

The telomeric transcriptome of Schizosaccharomyces pombe

(2011) Amadou Bah et al.   NUCLEIC ACIDS RESEARCH

The Paf1 complex: Platform or player in RNA polymerase II transcription?

(2010) Judith A. Jaehning   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping

(2010) James M Dewar et al.   EMBO JOURNAL

TERRA biogenesis, turnover and implications for function

(2010) Sascha Feuerhahn et al.   FEBS LETTERS

Molecular Dissection of Telomeric Repeat-Containing RNA Biogenesis Unveils the Presence of Distinct and Multiple Regulatory Pathways

(2010) A. Porro et al.   MOLECULAR AND CELLULAR BIOLOGY

The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase

(2010) Sophie Redon et al.   NUCLEIC ACIDS RESEARCH

Multiple Yeast Genes, Including Paf1 Complex Genes, Affect Telomere Length via Telomerase RNA Abundance

(2008) A. D. Mozdy et al.   MOLECULAR AND CELLULAR BIOLOGY

The Anchor-Away Technique: Rapid, Conditional Establishment of Yeast Mutant Phenotypes

(2008) Hirohito Haruki et al.   MOLECULAR CELL

The Rat1p 5′ to 3′ Exonuclease Degrades Telomeric Repeat-Containing RNA and Promotes Telomere Elongation in Saccharomyces cerevisiae

(2008) Brian Luke et al.   MOLECULAR CELL