Journal
NEURON
Volume 94, Issue 5, Pages 978-984Publisher
CELL PRESS
DOI: 10.1016/j.neuron.2017.05.025
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Funding
- National Institute of Neurological Disorder and Stroke [NS053603, NS094748, F31-NS092356]
- Commission of the European Union [FP7-PEOPLE-2013-IOF-627384]
- National Center for Medical Rehabilitation Research [T32-HD07418]
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The analysis of neural dynamics in several brain cortices has consistently uncovered low-dimensional manifolds that capture a significant fraction of neural variability. These neural manifolds are spanned by specific patterns of correlated neural activity, the neural modes. We discuss a model for neural control of movement in which the time-dependent activation of these neural modes is the generator of motor behavior. This mani-fold-based view of motor cortex may lead to a better understanding of how the brain controls movement.
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