Journal
NEUROGASTROENTEROLOGY AND MOTILITY
Volume 30, Issue 1, Pages -Publisher
WILEY
DOI: 10.1111/nmo.13238
Keywords
diet; dietary therapy; functional bowel disorders; inflammatory bowel disease; irritable bowel syndrome; predicting response (biomarkers)
Funding
- Canadian Institute of Health Research (CIHR), IMAGINE Strategy for Patient-Oriented Research (SPOR)
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BackgroundFunctional gastrointestinal symptoms in irritable bowel syndrome (IBS) and quiescent inflammatory bowel disease (IBD) cause significant morbidity and a reduction in quality of life. Multiple dietary therapies are now available to treat these symptoms, but supporting evidence for many is limited. In addition to a further need for studies demonstrating efficacy and mechanism of action of dietary therapies, the risk of nutritional inadequacy, alterations to the microbiome and changes in quality of life are key concerns requiring elucidation. Identifying predictors of response to dietary therapy is an important goal as management could be tailored to the individual to target specific dietary components, and thereby reduce the level of dietary restriction necessary. PurposeThis review discusses the available dietary therapies to treat symptoms in patients with IBS and patients with quiescent IBD suffering from IBS symptoms, with the aim to understand where current dietary evidence lies and how to move forward in dietary research in this field.
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