BDNF Contributes to Spinal Long-Term Potentiation and Mechanical Hypersensitivity Via Fyn-Mediated Phosphorylation of NMDA Receptor GluN2B Subunit at Tyrosine 1472 in Rats Following Spinal Nerve Ligation

Role of Fyn-mediated NMDA receptor function in prediabetic neuropathy in mice

(2016) Meng Suo et al.   JOURNAL OF NEUROPHYSIOLOGY

Molecular mechanism linking BDNF/TrkB signaling with the NMDA receptor in memory: the role of Girdin in the CNS

(2016) Norimichi Itoh et al.   REVIEWS IN THE NEUROSCIENCES

Potentiation of Synaptic GluN2B NMDAR Currents by Fyn Kinase Is Gated through BDNF-Mediated Disinhibition in Spinal Pain Processing

(2016) Michael E. Hildebrand et al.   Cell Reports

Astrocytes Promote Oligodendrogenesis after White Matter Damage via Brain-Derived Neurotrophic Factor

(2015) N. Miyamoto et al.   JOURNAL OF NEUROSCIENCE

BDNF contributes to the development of neuropathic pain by induction of spinal long-term potentiation via SHP2 associated GluN2B-containing NMDA receptors activation in rats with spinal nerve ligation

(2015) Xu Ding et al.   NEUROBIOLOGY OF DISEASE

Fyn kinase-regulated NMDA receptor- and AMPA receptor-dependent pain sensitization in spinal dorsal horn of mice

(2014) Y.N. Liu et al.   EUROPEAN JOURNAL OF PAIN

The induction of long-term potentiation in spinal dorsal horn after peripheral nociceptive stimulation and contribution of spinal TRPV1 in rats

(2014) F. Yang et al.   NEUROSCIENCE

NR2B Phosphorylation at Tyrosine 1472 Contributes to Brain Injury in a Rodent Model of Neonatal Hypoxia-Ischemia

(2014) Renatta Knox et al.   STROKE

Synaptic plasticity in pathological pain

(2014) Ceng Luo et al.   TRENDS IN NEUROSCIENCES

Src/p38 MAPK pathway in spinal microglia is involved in mechanical allodynia induced by peri-sciatic administration of recombinant rat TNF-α

(2013) Yu-Ying Li et al.   BRAIN RESEARCH BULLETIN

Fyn Regulates Adipogenesis by Promoting PIKE-A/STAT5a Interaction

(2013) Margaret Chui Ling Tse et al.   MOLECULAR AND CELLULAR BIOLOGY

Dietary omega-3 deficiency reduces BDNF content and activation NMDA receptor and Fyn in dorsal hippocampus: Implications on persistence of long-term memory in rats

(2013) Simone Azevedo Bach et al.   NUTRITIONAL NEUROSCIENCE

Involvement of Tyr1472 Phosphorylation of NMDA Receptor NR2B Subunit in Postherpetic Neuralgia in Model Mice

(2012) Sawako Unezaki et al.   Molecular Pain

Enhanced NMDA receptor tyrosine phosphorylation and increased brain injury following neonatal hypoxia–ischemia in mice with neuronal Fyn overexpression

(2012) Renatta Knox et al.   NEUROBIOLOGY OF DISEASE

HCV NS5A Protein Containing Potential Ligands for Both Src Homology 2 and 3 Domains Enhances Autophosphorylation of Src Family Kinase Fyn in B Cells

(2012) Kenji Nakashima et al.   PLoS One

Decreased dendritic spine density and abnormal spine morphology in Fyn knockout mice

(2011) Lenard W. Babus et al.   BRAIN RESEARCH

Metaplasticity gated through differential regulation of GluN2A versus GluN2B receptors by Src family kinases

(2011) Kai Yang et al.   EMBO JOURNAL

Regulation of NMDA receptors by the tyrosine kinase Fyn

(2011) Catherine H. Trepanier et al.   FEBS Journal

The regulation of N-methyl-d-aspartate receptors by Src kinase

(2011) Bradley R. Groveman et al.   FEBS Journal

NR2B phosphorylation at tyrosine 1472 in spinal dorsal horn contributed to N-methyl-D-aspartate-induced pain hypersensitivity in mice

(2011) Shuai Li et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Brain-derived neurotrophic factor contributes to spinal long-term potentiation and mechanical hypersensitivity by activation of spinal microglia in rat

(2010) Li-Jun Zhou et al.   BRAIN BEHAVIOR AND IMMUNITY

Decrease in the descending inhibitory 5-HT system in rats with spinal nerve ligation

(2010) Feng-Yu Liu et al.   BRAIN RESEARCH

Impairment of CaMKII activation and attenuation of neuropathic pain in mice lacking NR2B phosphorylated at Tyr1472

(2010) Shinji Matsumura et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Contribution of the spinal cord BDNF to the development of neuropathic pain by activation of the NR2B-containing NMDA receptors in rats with spinal nerve ligation

(2010) Shan-Jing Geng et al.   EXPERIMENTAL NEUROLOGY

cAMP-dependent protein kinase activated Fyn in spinal dorsal horn to regulate NMDA receptor function during inflammatory pain

(2010) Hong-Bin Yang et al.   JOURNAL OF NEUROCHEMISTRY

Involvement of spinal phosphorylation cascade of Tyr1472-NR2B, Thr286-CaMKII, and Ser831-GluR1 in neuropathic pain

(2010) Tayo Katano et al.   NEUROPHARMACOLOGY

Central sensitization: Implications for the diagnosis and treatment of pain

(2010) Clifford J. Woolf   PAIN

Fyn kinase is a direct molecular target of delphinidin for the inhibition of cyclooxygenase-2 expression induced by tumor necrosis factor-α

(2009) Mun Kyung Hwang et al.   BIOCHEMICAL PHARMACOLOGY

Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity

(2009) Alban Latremoliere et al.   JOURNAL OF PAIN

Caffeic acid, a phenolic phytochemical in coffee, directly inhibits Fyn kinase activity and UVB-induced COX-2 expression

(2008) N. J. Kang et al.   CARCINOGENESIS

Activation of Fyn tyrosine kinase in the mouse dorsal hippocampus is essential for contextual fear conditioning

(2008) Tomoko Isosaka et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Role of the spinal cord NR2B-containing NMDA receptors in the development of neuropathic pain

(2008) Xiao-Xiu Qu et al.   EXPERIMENTAL NEUROLOGY

BDNF Modulation of NMDA Receptors Is Activity Dependent

(2008) Robert A. Crozier et al.   JOURNAL OF NEUROPHYSIOLOGY

Post-synaptic density-93 mediates tyrosine-phosphorylation of the N-methyl-d-aspartate receptors

(2008) Y. Sato et al.   NEUROSCIENCE

Src family kinases: Regulation of their activities, levels and identification of new pathways

(2007) Evan Ingley   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS