Journal
NEURO-OPHTHALMOLOGY
Volume 42, Issue 4, Pages 237-241Publisher
TAYLOR & FRANCIS AS
DOI: 10.1080/01658107.2017.1374982
Keywords
Amyloid angiopathy; inflammation; neuro-ophthalmology; retina
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Amyloid beta-related angiitis (ABRA) is a subtype of cerebral amyloid angiopathy-related inflammation, with distinctive pathology and prognosis compared with cerebral amyloid angiopathy (CAA). On a spectrum of increasing severity, ABRA is considered to be in-between the less aggressive inflammatory-CAA and the more severe primary central nervous system (CNS) angiitis. Whereas retinal pathological changes were described in subjects with primary or secondary CNS angiitis, and non-inflammatory CAA, bilateral posterior pole superficial and peripapillary retinal hemorrhages have not been reported as initial signs in patients with pathology-confirmed ABRA, accompanying neurological spells and characteristic neuroimaging findings.
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