3.8 Article

What Do Transgender Patients Teach Us About Idiopathic Intracranial Hypertension?

Journal

NEURO-OPHTHALMOLOGY
Volume 41, Issue 6, Pages 326-329

Publisher

TAYLOR & FRANCIS AS
DOI: 10.1080/01658107.2017.1316744

Keywords

Androgens; gender reassignment; idiopathic intracranial hypertension; papilloedema testosterone

Funding

  1. Association of British Neurologists
  2. NIHR Clinician Scientist Fellowship [NIHR-CS-011-028]
  3. Medical Research Council, UK [MR/K015184/1]
  4. Medical Research Council [G0601430, MR/K015184/1] Funding Source: researchfish
  5. National Institute for Health Research [NIHR-CS-011-028, ACF-2016-09-005, CL-2009-09-001] Funding Source: researchfish
  6. MRC [MR/K015184/1, G0601430] Funding Source: UKRI

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Idiopathic intracranial hypertension (IIH), a condition of raised intracranial pressure, is characterised by headaches and visual disturbances. Its pathogenesis is currently unknown; however, dysregulation of androgens may be implicated. Here, the authors present a case of a 22-year-old patient undergoing female-to-male (FTM) gender reassignment who developed IIH shortly after commencing testosterone therapy. This interesting case presents the possibility of androgens having a pathogenic role in IIH.

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