Article
Materials Science, Textiles
Saleh S. Abdelhady, M. M. Atta, A. A. Megahed, K. A. Abu-Hasel, Mohammed Alquraish, Ashraf A. Ali, Said H. Zoalfakar
Summary: This study attempted to model the diameter of Poly Lactic-co-Glycolic Acid (PLGA) nanofibers using response surface methodology (RSM) and artificial neural networks (ANNs), aiming to determine the optimal electrospinning process conditions for producing the smallest fiber diameter. The results showed that ANN performed better in predicting nanofiber diameter compared to RSM, and the optimal network structure was determined. The experimental and predicted results demonstrated a strong correlation, indicating the good predictability of the ANN model. The RSM model yielded the optimum combinations for electrospinning PLGA nanofibers that can achieve fine, consistent, and high-quality results.
JOURNAL OF INDUSTRIAL TEXTILES
(2022)
Article
Environmental Sciences
Vinicius Luiz Pacheco, Lucimara Bragagnolo, Francisco Dalla Rosa, Antonio Thome
Summary: This study compares the optimization of specific urease activity (SUA) and calcium carbonate (CaCO3) using microbially induced calcite precipitation (MICP) with three machine learning algorithms: random forest regressor, artificial neural networks (ANNs), and multivariate linear regression. The random forest-based algorithm performs the best with improved r(2) values of 0.9381 and 0.9463.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Engineering, Environmental
Muhammad Yaqub, Changyeon Woo, Wontae Lee
Summary: The study investigated the production of hypochlorous acid through electrolysis, studied the effects of various parameters on the yield, identified the optimal operating parameters using response surface methodology, and found that feed water flow rate, acid concentration, and acid dosing pump stroke were significant influencing factors.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Green & Sustainable Science & Technology
Bilge Coskuner Filiz, Beyza Nur Kinsiz, Serpil Kilic Depren, Aysel Kanturk Figen
Summary: This study presents a catalyst regeneration strategy based on solvent washing to restore the high initial catalytic activity of Co-based catalysts. The results showed that solvent washing at optimal conditions was an effective method for restoring the activity. This research is significant for the application of ammonia borane as a hydrogen storage medium and the release of hydrogen for hydrogen energy systems.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Engineering, Chemical
Ana Rita Silva, Manuel Ayuso, Taofiq Oludemi, Alexandre Goncalves, Bruno Melgar, Lillian Barros
Summary: This study optimized the extraction of three major phenolic compounds from olive pomace using microwave- and ultrasonic-assisted methods. The results showed that the microwave-assisted method was more effective and temperature had a significant impact on the extraction of phenolic compounds.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Metallurgy & Metallurgical Engineering
Freddy A. Lucay, Mauricio Sales-Cruz, Edelmira D. Galvez, Luis A. Cisternas
Summary: The study presents a methodology for obtaining response surfaces when a small data set is available and its behavior is complex. By using experimental design, kriging, artificial neural network, and hybrid algorithm, the model's robustness and stability are guaranteed, leading to better optimal conditions.
MINERAL PROCESSING AND EXTRACTIVE METALLURGY REVIEW
(2021)
Article
Engineering, Chemical
Miguel Rebollo-Hernanz, Silvia Canas, Diego Taladrid, Angela Segovia, Begona Bartolome, Yolanda Aguilera, Maria A. Martin-Cabrejas
Summary: This study aimed to establish and optimize a green extraction method for phenolic compounds from cocoa shell, obtaining high-value products and validating the model through experiments. The results showed that temperature, solid-to-liquid ratio, and acidity were the main factors affecting phenolic extraction. Fifteen phenolic compounds were identified in the extracts, with potential use as food-grade ingredients and nutraceutical products.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Engineering, Chemical
Ayrton Alef Castanheira Pereira, Carlos Alberto Castaneda Olivera, Antonio Gutierrez Merma, Ronald Rojas Hacha, Brunno Ferreira dos Santos, Mauricio Leonardo Torem
Summary: This study investigated the use of polynomial modeling and artificial neural network techniques for optimizing bioflotation parameters in the separation of carbonate gangue minerals from phosphate ores. Results showed that artificial neural network models had higher adequacy in describing and predicting mineral recovery compared to polynomial models. A more acidic medium and higher biosurfactant concentration were found to increase mineral recovery.
MINERALS ENGINEERING
(2021)
Article
Chemistry, Physical
Muhammad Irfan, Sharjeel Waqas, Ushtar Arshad, Javed Akbar Khan, Stanislaw Legutko, Izabela Kruszelnicka, Dobrochna Ginter-Kramarczyk, Saifur Rahman, Anna Skrzypczak
Summary: This study successfully reduced membrane fouling by optimizing the operating parameters in a membrane rotating biological contactor. The application of optimized process parameters can improve treatment efficiency, save time and resources, and protect human health and the environment.
Article
Food Science & Technology
Sara Nanvakenari, Kamyar Movagharnejad, Asefeh Latifi
Summary: This study investigated the effects of different fluidization regimes and temperatures of a fluidized bed dryer on rice drying time and quality properties. The experiments found that a fluidized bed dryer with ventilation significantly improved head rice yield and whiteness index compared to a dryer without ventilation. Optimization using response surface methodology resulted in the best drying conditions for both lowest drying time and highest quality parameters.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Pharmacology & Pharmacy
Miguel O. Jara, Mariana Landin, Javier O. Moralesa
Summary: The study utilized neurofuzzy logic (NFL) for fabricating polycaprolactone nanoparticles and found that stabilizer selection is crucial in preventing nanoparticle aggregation. Fluid dynamics-related inputs were also important in tuning the characteristics of stabilized nanoparticles.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Agricultural Engineering
Soraya Soleimani, Amir Heydari, Moslem Fattahi
Summary: In this study, calcium alginate (CA) hydrogels were synthesized using the ion-exchange method and enhanced with cellulose nanocrystals (CNC). The swelling property of the hydrogels was investigated, and the CNC-reinforced hydrogels (CA/CNC) with higher swelling ratio were selected for further tests. The effect of independent variables on the swelling of CA/CNC was analyzed using response surface method based on central composite design (RSM-CCD) and artificial neural network-salp swarm algorithm (ANN-SSA) hybrid. The results showed that ANN-SSA was more precise than RSM in analyzing the influence of sodium alginate concentration, calcium chloride concentration, and CNC concentration on hydrogel swelling.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Environmental Sciences
Julie Baruah, Chayanika Chaliha, Bikash Kar Nath, Eeshan Kalita
Summary: A novel nanobiosorbent derived from waste molasses was developed for adsorptive removal of arsenic, showing high efficiency and potential for commercial applications. The synthesis and characterization of the iron oxide incorporated carbonaceous nanomaterial were confirmed through various analyses. Optimization through artificial neural network modeling improved adsorption efficiency and mechanism elucidation.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Polymer Science
Shulin Yang, Xiaokang Tian, Qingsong Zhang, Jicheng Jiang, Panpan Dong, Jianguo Tan, Yubin Meng, Pengfei Liu, Haihui Bai, Jinzhi Song
Summary: This paper optimized the preparation process of yeast fermentation multistage porous hydrogels using mathematical analysis and experimental design. The significant influencing factors were determined using analysis of variance, and the optimal preparation conditions were predicted using response surface methodology and artificial neural network. The results showed that these methods were effective in optimizing the preparation of porous hydrogels.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Agricultural Engineering
Apoorva Upadhyay, Andrey A. Kovalev, Elena A. Zhuravleva, Nidhi Pareek, Vivekanand Vivekanand
Summary: Acetic acid bacteria (AAB) were isolated from fruit waste and cow dung based on their potential to produce acetic acid. The AAB were identified using a halo-zone method on agar plates containing Glucose-Yeast extract-Calcium carbonate (GYC media). The highest acetic acid yield of 4.88 g/100 ml was reported from a bacterial strain isolated from apple waste. The study found that glucose concentration and incubation period, as well as their interaction, had a significant effect on acetic acid yield, as determined through Response Surface Methodology (RSM) and Artificial Neural Network (ANN) modeling. Biological production of acetic acid from food waste can be a sustainable and environmentally friendly approach in the circular economy.
BIORESOURCE TECHNOLOGY
(2023)
Article
Multidisciplinary Sciences
Hossein Siampour, Sara Abbasian, Ahmad Moshaii, Kobra Omidfar, Mosslim Sedghi, Hossein Naderi-Manesh
SCIENTIFIC REPORTS
(2020)
Article
Chemistry, Multidisciplinary
Hadi Hashemzadeh, Abdollah Allahverdi, Mosslim Sedghi, Zahra Vaezi, Tahereh Tohidi Moghadam, Mario Rothbauer, Michael Bernhard Fischer, Peter Ertl, Hossein Naderi-Manesh
Article
Biochemistry & Molecular Biology
Najme Dehghanbanadaki, Majid Taghdir, Hossein Naderi-Manesh
Summary: The Wnt/β-catenin signaling pathway is dysregulated in many human cancers, and atrial natriuretic peptide (ANP) may inhibit Wnt signaling by competitively binding to Frizzled (FZD). Molecular dynamics studies reveal overlapping binding regions for ANP and Wnt on FZD7, potentially preventing the formation of the Wnt-FZD complex. This suggests that ANP could serve as a scaffold for designing selective inhibitors against FZD-dependent cancers.
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS
(2021)
Article
Nanoscience & Nanotechnology
Zahra Vaezi, Mosslim Sedghi, Mohammad Ghorbani, Seyedehsamaneh Shojaeilangari, Abdollah Allahverdi, Hossein Naderi-Manesh
MICROFLUIDICS AND NANOFLUIDICS
(2020)
Article
Pharmacology & Pharmacy
Parvaneh Peyvand, Zahra Vaezi, Mosslim Sedghi, Nima Dalir, Leila Ma'mani, Hossein Naderi-Manesh
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
(2020)
Article
Oncology
Javid Esfandyari, Behnaz Shojaedin-Givi, Hadi Hashemzadeh, Mohammad Mozafari-Nia, Zahra Vaezi, Hossein Naderi-Manesh
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2020)
Article
Chemistry, Multidisciplinary
Abdolali Alizadeh, Behnaz Farajpour, Sanam Sadeghi Mohammadi, Mosslim Sedghi, Hossein Naderi-Manesh, Christoph Janiak, Tim-Oliver Knedel
Article
Biochemistry & Molecular Biology
Sharareh Tavaddod, Behnaz Shojaedin-Givi, Mahnaz Mahmoudi-Rad, Hossein Naderi-Manesh
Summary: The study investigated the morphology of label-free primary melanocytes and melanoma cells using light microscopy and image processing. A novel approach based on nuclear body morphology was used to identify single cells at the same phase of the cell cycle. Quantification of the area and perimeter of the cells revealed significant differences between adendritic-shaped melanocytes and melanoma cells, leading to the proposal of a theoretical model based on dendrite loss that aligned with experimental data.
CELL BIOCHEMISTRY AND BIOPHYSICS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Neshat Eghbali, Homam Naffakh-Moosavy, Sanam Sadeghi Mohammadi, Hossein Naderi-Manesh
Summary: The micro-nano scale surface modification of Ti-6Al-4V using fiber engraving laser method showed significant enhancement in cell adhesion and antibacterial properties. Different laser frequencies and groove distances affected cellular viability, bacterial adhesion, and other surface characteristics.
Article
Chemistry, Inorganic & Nuclear
Mina Fatahian-Nezhad, Robabeh Alizadeh, Sanam Sadeghi Mohammadi, Mohammad Tohidlou, Hossein Naderi-Manesh, Vahid Amani
Summary: The Pd(II) complexes were synthesized and characterized, demonstrating binding to DNA and anti-tumor properties. The 5,6-dmphen ligand showed significant cytotoxicity and played a crucial role in the cytotoxic activity of the complexes.
INORGANICA CHIMICA ACTA
(2021)
Article
Multidisciplinary Sciences
Hadi Hashemzadeh, Seyedehsamaneh Shojaeilangari, Abdollah Allahverdi, Mario Rothbauer, Peter Ertl, Hossein Naderi-Manesh
Summary: Lung cancer is a major cause of cancer-related deaths worldwide, with high mortality rates attributed to late-stage diagnoses and metastasis. Deep learning algorithms, particularly ResNet18, show promise in accurately categorizing lung cancer cell lines, offering efficient and accurate results for automated diagnostic systems.
SCIENTIFIC REPORTS
(2021)
Article
Cell Biology
Hadi Hashemzadeh, Ali Hamad Abd Kelkawi, Abdollah Allahverdi, Mario Rothbauer, Peter Ertl, Hossein Naderi-Manesh
Summary: The inadequacy of animal models has led to the development of improved in vitro models, such as 3D multicellular spheroids, for drug efficacy assessments. While these models provide physiological relevance and meet high-throughput and low-cost requirements for drug discovery, their application in nanotoxicity testing is still in its early stages due to limited penetration and uptake rates. Comparative studies between 2D monolayer cultures and 3D spheroids revealed distinct cellular responses to gold nanowires (AuNWs) treatment, emphasizing the need for more physiologically relevant tissue models for investigating nanomaterial-biology interactions.
Article
Chemistry, Multidisciplinary
Rashin Mohammadi, Mohammad Asghari, Monika Colombo, Zahra Vaezi, Daniel A. Richards, Stavros Stavrakis, Hossein Naderi-Manesh, Andrew DeMello
Summary: This study presents the design and optimization of a microfluidic device that can automatically isolate circulating tumor cells (CTCs) from whole blood, which is challenging due to the low concentration of CTCs and their mixture with other blood components. The device achieves separation through passive viscoelastic separation and subsequent active magnetophoretic separation. Magnetic biosilica frustules are used for tagging and magnetic isolation of CTCs. The platform demonstrates high recovery and purity of CTCs.
Article
Nanoscience & Nanotechnology
Mojtaba Shamsipur, Elaheh Babaee, Mohammad-Bagher Gholivand, Fatemeh Molaabasi, Farimah Mousavi, Ali Barati, Behnam Hajipour Verdom, Behnaz Shojaedin-Givi, Hossein Naderi-Manesh
Summary: In this study, a new fluorescence probe based on insulin-capped gold nanoclusters (Ins/Au-NCs) was developed for selective detection of Cu2+ ions and glutathione (GSH). The probe showed high sensitivity and stability. Cu2+ ions caused fluorescence quenching of Ins/Au-NCs, which could be recovered in the presence of GSH. The probe had low detection limits and broad linear ranges for Cu2+ ions and GSH. It also showed promising application in detecting low levels of Cu2+ ions and GSH in water and human serum samples.
ACS APPLIED NANO MATERIALS
(2023)
Article
Pharmacology & Pharmacy
Seyed Mohammad Reza Mortazavi, Zahra Vaezi, Reza Mahdavian, Mohsen Barzegar, Hossein Naderi-Manesh
Summary: In order to treat inflammatory bowel disease (IBD), researchers are developing a local drug delivery system. In this study, a novel composite cerasome was prepared by mixing organosilane-based oleic acid with 1,2-dipalmitoyl-sn-glycero-3-phosphocholine. The results show that this novel cerasome has great potential as a non-ulcerogenic agent in IBD therapy.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)