Analysis of metabolites in single cells-what is the best micro-platform?

An adaptable stage perfusion incubator for the controlled cultivation of C2C12 myoblasts

(2015) Felix Kurth et al.   ANALYST

Molecular phenotypic profiling of a Saccharomyces cerevisiae strain at the single-cell level

(2014) A. Mareike Schmidt et al.   ANALYST

Current trends in single cell analysis

(2014) Petra Dittrich et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

A New Microfluidics-Based Droplet Dispenser for ICPMS

(2014) Pascal E. Verboket et al.   ANALYTICAL CHEMISTRY

On-Chip Enzyme Quantification of Single Escherichia coli Bacteria by Immunoassay-based Analysis

(2014) Simone Stratz et al.   ANALYTICAL CHEMISTRY

Single-cell transcriptomics for microbial eukaryotes

(2014) Martin Kolisko et al.   CURRENT BIOLOGY

Cytosolic pH Regulates Cell Growth through Distinct GTPases, Arf1 and Gtr1, to Promote Ras/PKA and TORC1 Activity

(2014) Reinhard Dechant et al.   MOLECULAR CELL

Single-cell western blotting

(2014) Alex J Hughes et al.   NATURE METHODS

Calorie restriction does not elicit a robust extension of replicative lifespan in Saccharomyces cerevisiae

(2014) D. H. E. W. Huberts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zooming in to see the bigger picture: Microfluidic and nanofabrication tools to study bacteria

(2014) Felix J. H. Hol et al.   SCIENCE

Single Cell Genomics: Advances and Future Perspectives

(2014) Iain C. Macaulay et al.   PLoS Genetics

Analysis of single algal cells by combining mass spectrometry with Raman and fluorescence mapping

(2013) Stephan R. Fagerer et al.   ANALYST

Implementing Enzyme-Linked Immunosorbent Assays on a Microfluidic Chip To Quantify Intracellular Molecules in Single Cells

(2013) K. Eyer et al.   ANALYTICAL CHEMISTRY

High Yield Patterning of Single Cells from Extremely Small Populations

(2013) Andrea Faenza et al.   ANALYTICAL CHEMISTRY

Programmable Interactions of Functionalized Single Bioparticles in a Dielectrophoresis-Based Microarray Chip

(2013) Melanie Abonnenc et al.   ANALYTICAL CHEMISTRY

Interfacing Droplet Microfluidics with Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry: Label-Free Content Analysis of Single Droplets

(2013) Simon K. Küster et al.   ANALYTICAL CHEMISTRY

Metabolic Differences in Microbial Cell Populations Revealed by Nanophotonic Ionization

(2013) Bennett N. Walker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Interrogating Biology with Force: Single Molecule High-Resolution Measurements with Optical Tweezers

(2013) Marco Capitanio et al.   BIOPHYSICAL JOURNAL

Single Cell Optical Imaging and Spectroscopy

(2013) Anthony S. Stender et al.   CHEMICAL REVIEWS

Advances in high-throughput single-cell microtechnologies

(2013) Westbrook M Weaver et al.   CURRENT OPINION IN BIOTECHNOLOGY

Mass spectrometry-based metabolomics of single yeast cells

(2013) A. J. Ibanez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-Cell Metabolomics: Analytical and Biological Perspectives

(2013) R. Zenobi   SCIENCE

Single-Cell Metabolomics: Changes in the Metabolome of Freshly Isolated and Cultured Neurons

(2012) Peter Nemes et al.   ACS Chemical Neuroscience

On-Target Labeling of Intracellular Metabolites Combined with Chemical Mapping of Individual Hyphae Revealing Cytoplasmic Relocation of Isotopologues

(2012) Jie-Bi Hu et al.   ANALYTICAL CHEMISTRY

Chemical Analysis of Single Cells

(2012) Raphaël Trouillon et al.   ANALYTICAL CHEMISTRY

Chip-based separation devices coupled to mass spectrometry

(2012) Stefan Ohla et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A facile protocol for the immobilisation of vesicles, virus particles, bacteria, and yeast cells

(2012) Phillip Kuhn et al.   Integrative Biology

Targeted isolation and analysis of single tumor cells with aptamer-encoded microwell array on microfluidic device

(2012) Qiushui Chen et al.   LAB ON A CHIP

Accurate Detection of Carcinoma Cells by Use of a Cell Microarray Chip

(2012) Shohei Yamamura et al.   PLoS One

Isotope Label-Aided Mass Spectrometry Reveals the Influence of Environmental Factors on Metabolism in Single Eggs of Fruit Fly

(2012) Te-Wei Tseng et al.   PLoS One

Single-Cell Analysis in Biotechnology, Systems Biology, and Biocatalysis

(2012) Frederik S.O. Fritzsch et al.   Annual Review of Chemical and Biomolecular Engineering

Monitoring induced gene expression of single cells in a multilayer microchip

(2011) C. Hanke et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Chemical Analysis of Single Cells

(2011) Yuqing Lin et al.   ANALYTICAL CHEMISTRY

Single-cell metabolomics comes of age: new developments in mass spectrometry profiling and imaging

(2011) Aleš Svatoš   ANALYTICAL CHEMISTRY

Imaging Single-Cell Signaling Dynamics with a Deterministic High-Density Single-Cell Trap Array

(2011) Kwanghun Chung et al.   ANALYTICAL CHEMISTRY

Cellular heterogeneity and live cell arrays

(2011) Maureen A. Walling et al.   CHEMICAL SOCIETY REVIEWS

Microfluidic array cytometer based on refractive optical tweezers for parallel trapping, imaging and sorting of individual cells

(2011) Michael Werner et al.   LAB ON A CHIP

A microchamber array for single cell isolation and analysis of intracellular biomolecules

(2011) Klaus Eyer et al.   LAB ON A CHIP

Carbon-13 labelling strategy for studying the ATP metabolism in individual yeast cells by micro-arrays for mass spectrometry

(2011) Pawel L. Urban et al.   Molecular BioSystems

Metabolite extraction from suspension-cultured mammalian cells for global metabolite profiling

(2011) Christopher A Sellick et al.   Nature Protocols

Towards quantitative metabolomics of mammalian cells: Development of a metabolite extraction protocol

(2010) Stefanie Dietmair et al.   ANALYTICAL BIOCHEMISTRY

Integrated Microfluidic Device for Automated Single Cell Analysis Using Electrophoretic Separation and Electrospray Ionization Mass Spectrometry

(2010) J. Scott Mellors et al.   ANALYTICAL CHEMISTRY

Manipulation of Suspended Single Cells by Microfluidics and Optical Tweezers

(2010) Nathalie Nève et al.   Cellular and Molecular Bioengineering

High-density micro-arrays for mass spectrometry

(2010) Pawel L. Urban et al.   LAB ON A CHIP

Rapid and Highly Sensitive Detection of Malaria-Infected Erythrocytes Using a Cell Microarray Chip

(2010) Shouki Yatsushiro et al.   PLoS One

Microfluidic sorting and multimodal typing of cancer cells in self-assembled magnetic arrays

(2010) A.-E. Saliba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dilution-Free Analysis from Picoliter Droplets by Nano-Electrospray Ionization Mass Spectrometry

(2009) Ryan T. Kelly et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Coupling Microdroplet Microreactors with Mass Spectrometry: Reading the Contents of Single Droplets Online

(2009) Luis M. Fidalgo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Antibody Elution Method for Multiple Immunohistochemistry on Primary Antibodies Raised in the Same Species and of the Same Subtype

(2009) Daniel Pirici et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Droplet microfluidic technology for single-cell high-throughput screening

(2009) E. Brouzes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global Metabolic Profiling ofEscherichia coliCultures:  an Evaluation of Methods for Quenching and Extraction of Intracellular Metabolites

(2008) Catherine L. Winder et al.   ANALYTICAL CHEMISTRY

Single-Molecule Approach to Molecular Biology in Living Bacterial Cells

(2008) X. Sunney Xie et al.   Annual Review of Biophysics

A cellular isolation system for real-time single-cell oxygen consumption monitoring

(2008) J. Dragavon et al.   Journal of the Royal Society Interface

Analyzing cell mechanics in hematologic diseases with microfluidic biophysical flow cytometry

(2008) Michael J. Rosenbluth et al.   LAB ON A CHIP

The Envirostat – a new bioreactor concept

(2008) Hendrik Kortmann et al.   LAB ON A CHIP

Leakage-free rapid quenching technique for yeast metabolomics

(2008) André B. Canelas et al.   Metabolomics

From biomarkers to integrated network responses

(2008) Uwe Sauer et al.   NATURE BIOTECHNOLOGY

The chemistrode: A droplet-based microfluidic device for stimulation and recording with high temporal, spatial, and chemical resolution

(2008) D. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA