Urea and chronic kidney disease: the comeback of the century? (in uraemia research)

Effect of Synbiotic Therapy on Gut-Derived Uremic Toxins and the Intestinal Microbiome in Patients with CKD

(2016) N. D. Vaziri   Clinical Journal of the American Society of Nephrology

Urea impairs β cell glycolysis and insulin secretion in chronic kidney disease

(2016) Laetitia Koppe et al.   JOURNAL OF CLINICAL INVESTIGATION

HEMO Revisited: Why Kt/Vurea Only Tells Part of the Story

(2016) B. Meijers et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Kt/Vurea and Nonurea Small Solute Levels in the Hemodialysis Study

(2016) T. W. Meyer et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Reconsidering the Lack of Urea Toxicity in Dialysis Patients

(2016) Ziad A. Massy et al.   SEMINARS IN DIALYSIS

Urea-induced ROS cause endothelial dysfunction in chronic renal failure

(2015) Maria D'Apolito et al.   ATHEROSCLEROSIS

Plasma levels of trimethylamine-N-oxide are confounded by impaired kidney function and poor metabolic control

(2015) Daniel M. Mueller et al.   ATHEROSCLEROSIS

Associations of Trimethylamine N-Oxide With Nutritional and Inflammatory Biomarkers and Cardiovascular Outcomes in Patients New to Dialysis

(2015) George A. Kaysen et al.   JOURNAL OF RENAL NUTRITION

Kt/V (and especially its modifications) remains a useful measure of hemodialysis dose

(2015) John T. Daugirdas   KIDNEY INTERNATIONAL

Once upon a time in dialysis: the last days of Kt/V?

(2015) Raymond Vanholder et al.   KIDNEY INTERNATIONAL

Protein carbamylation is associated with heart failure and mortality in diabetic patients with end-stage renal disease

(2015) Christiane Drechsler et al.   KIDNEY INTERNATIONAL

Urea and protein carbamylation in ESRD: surrogate markers or partners in crime?

(2015) Manuel T. Velasquez et al.   KIDNEY INTERNATIONAL

Protein carbamylation is a hallmark of aging

(2015) Laëtitia Gorisse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of Prominent Trimethylamine Oxide (TMAO) Accumulation in Hemodialysis Patients

(2015) Xin Hai et al.   PLoS One

Protein Carbamylation in Kidney Disease: Pathogenesis and Clinical Implications

(2014) Sahir Kalim et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Expansion of Urease- and Uricase-Containing, Indole- and p-Cresol-Forming and Contraction of Short-Chain Fatty Acid-Producing Intestinal Microbiota in ESRD

(2014) Jakk Wong et al.   AMERICAN JOURNAL OF NEPHROLOGY

The Uremic Toxicity of Indoxyl Sulfate and p-Cresyl Sulfate: A Systematic Review

(2014) R. Vanholder et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The urea decomposition product cyanate promotes endothelial dysfunction

(2014) Dalia El-Gamal et al.   KIDNEY INTERNATIONAL

Oral Activated Charcoal Adsorbent (AST-120) Ameliorates Chronic Kidney Disease-Induced Intestinal Epithelial Barrier Disruption

(2013) Nosratola D. Vaziri et al.   AMERICAN JOURNAL OF NEPHROLOGY

Chronic Increase of Urea Leads to Carbamylated Proteins Accumulation in Tissues in a Mouse Model of CKD

(2013) Christine Pietrement et al.   PLoS One

Uremic Plasma Impairs Barrier Function and Depletes the Tight Junction Protein Constituents of Intestinal Epithelium

(2012) Nosratola D. Vaziri et al.   AMERICAN JOURNAL OF NEPHROLOGY

Role of Urea in Intestinal Barrier Dysfunction and Disruption of Epithelial Tight Junction in Chronic Kidney Disease

(2012) Nosratola D. Vaziri et al.   AMERICAN JOURNAL OF NEPHROLOGY

In vivo assessment of bacteriotherapy on acetaminophen-induced uremic rats

(2012) Arpita Mandal et al.   JOURNAL OF NEPHROLOGY

Normal and Pathologic Concentrations of Uremic Toxins

(2012) F. Duranton et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Upregulation of BAD, a pro-apoptotic protein of the BCL2 family, in vascular smooth muscle cells exposed to uremic conditions

(2011) Eric Trécherel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Disintegration of colonic epithelial tight junction in uremia: a likely cause of CKD-associated inflammation

(2011) Nosratola D. Vaziri et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Circulating Endotoxemia: A Novel Factor in Systemic Inflammation and Cardiovascular Disease in Chronic Kidney Disease

(2010) C. W. McIntyre et al.   Clinical Journal of the American Society of Nephrology

Chronic Uremia Stimulates LDL Carbamylation and Atherosclerosis

(2010) E. O. Apostolov et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

In-Center Hemodialysis Six Times per Week versus Three Times per Week

(2010)   NEW ENGLAND JOURNAL OF MEDICINE

Serum Indoxyl Sulfate Is Associated with Vascular Disease and Mortality in Chronic Kidney Disease Patients

(2009) F. C. Barreto et al.   Clinical Journal of the American Society of Nephrology

Urea-induced ROS generation causes insulin resistance in mice with chronic renal failure

(2009) Maria D’Apolito et al.   JOURNAL OF CLINICAL INVESTIGATION

The General Picture of Uremia

(2009) Cyrielle Almeras et al.   SEMINARS IN DIALYSIS

A Bench to Bedside View of Uremic Toxins

(2008) R. Vanholder et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Dual role of proapoptotic BAD in insulin secretion and beta cell survival

(2008) Nika N Danial et al.   NATURE MEDICINE