Review
Urology & Nephrology
Connie M. Rhee, Csaba P. Kovesdy, Kamyar Kalantar-Zadeh
Summary: Chronic kidney disease is a common and serious complication of diabetes mellitus, contributing significantly to kidney disease burden. Understanding optimal management strategies to reduce cardiovascular risk and improve survival rates is crucial for diabetic patients with CKD.
SEMINARS IN NEPHROLOGY
(2021)
Review
Oncology
Giovanni Maria Iannantuono, Lidia Strigari, Mario Roselli, Francesco Torino
Summary: Burned out or burnt out testicular cancer (BTC) refers to the spontaneous and complete regression of testicular germ cell tumor in the presence of distant metastases at diagnosis. The study found inconsistencies in the diagnosis and treatment of BTC, highlighting the need for larger collaborative studies to define the best approach for these patients.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
(2021)
Review
Urology & Nephrology
Connie M. Rhee, Kamyar Kalantar-Zadeh, Katherine R. Tuttle
Summary: Diabetes mellitus is a leading cause of chronic kidney disease (CKD), and recent studies have shown that even CKD patients without diabetes mellitus are at heightened risk for hypoglycemia. In patients transitioning to end-stage renal disease (ESRD), the phenomenon of "burnt-out diabetes" is observed, where hyperglycemia resolves and hypoglycemia becomes frequent. Hypoglycemia is causally associated with mortality, and it is important to implement strategies to prevent dysglycemia in CKD and ESRD patients.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
(2022)
Review
Endocrinology & Metabolism
Maurizio Gallieni, Cristina De Salvo, Maria Elena Lunati, Antonio Rossi, Francesca D'Addio, Ida Pastore, Gianmarco Sabiu, Roberta Miglio, Gian Vincenzo Zuccotti, Paolo Fiorina
Summary: Diabetic kidney disease is the primary cause of end-stage kidney disease in high-income countries. It is challenging to control glycemic fluctuations in uremic patients, making continuous glucose monitoring an ideal tool for managing diabetes in hemodialysis patients. Studies have shown that continuous glucose monitoring is more accurate and easier to use than glycated hemoglobin testing, especially in patients with type 2 diabetes on hemodialysis.
ACTA DIABETOLOGICA
(2021)
Article
Psychology, Multidisciplinary
Eilidh Cage, Ellie McManemy
Summary: Autistic students are more likely to drop out of university and experience higher levels of burnout and mental health symptoms compared to non-autistic students during the COVID-19 pandemic. Universities should enhance both academic and social support to promote equal opportunities for autistic students in Higher Education.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Psychology, Multidisciplinary
Elisa Konya-Baumbach, Miriam Biller, Sergej von Janda
Summary: This study examines the effectiveness of chatbot anthropomorphism in customer interactions and finds significant positive effects on trust, purchase intention, word of mouth, and satisfaction with the shopping experience. The study suggests that social presence serves as a critical mediating mechanism in these effects.
COMPUTERS IN HUMAN BEHAVIOR
(2023)
Article
Cardiac & Cardiovascular Systems
Juan M. Pericas, Jaume Llopis, Maria Jesus Jimenez-Exposito, Wissam M. Kourany, Benito Almirante, Giampiero Carosi, Emanuele Durante-Mangoni, Claudio Querido Fortes, Efthymia Giannitsioti, Stamatios Lerakis, Rodrigo Montagna-Mella, Juan Ambrosioni, Ru-San Tan, Carlos A. Mestres, Dannah Wray, Orathai Pachirat, Asuncion Moreno, Vivian H. Chu, Elisa de Lazzari, Vance G. Fowler, Jose M. Miro
Summary: In patients receiving chronic hemodialysis, infective endocarditis (IE) is a common and serious complication characterized by higher mortality and relapse rates compared to non-HD patients. Additionally, cardiac surgery is less frequently performed in HD patients.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Review
Oncology
Yuya Nagai, Alexander J. Ambinder
Summary: The use of retinoids in cancer treatment and prevention has shown both successes and disappointments. All-trans retinoic acid (ATRA) has been effective in curing acute promyelocytic leukemia (APL), but has limited efficacy in other types of acute myeloid leukemia (AML). Vitamin A supplementation as a cancer prevention strategy has been ineffective and may increase the risk of lung cancer. Recent studies have shown that synthetic retinoids have potential in treating AML, especially in subsets of the disease that are sensitive to these compounds.
Article
Oncology
Jana Stojanova, Jane E. Carland, Bridin Murnion, Vincent Seah, Jim Siderov, Florian Lemaitre
Summary: Pharmacological therapy is the main treatment for cancer patients, but dosing based on body size is still the predominant approach. Therapeutic drug monitoring (TDM) in oncology remains insufficient, with a lack of studies related to clinical outcomes. Therefore, there is a need to fill the evidence gaps and improve the uptake of TDM in oncology.
FRONTIERS IN ONCOLOGY
(2022)
Article
Endocrinology & Metabolism
Orianne Villard, Marc D. Breton, Swati Rao, Mary K. Voelmle, Morgan R. Fuller, Helen E. Myers, Ryan K. McFadden, Zander S. Luke, Christian A. Wakeman, Mary Clancy-Oliveri, Ananda Basu, Meaghan M. Stumpf
Summary: This study assessed the accuracy and clinical relevance of a factory-calibrated CGM in individuals on hemodialysis. The results showed that the CGM had reasonably accurate performance and is clinically relevant for improving diabetes management in this population.
Article
Hematology
Kazunori Karasawa, Shota Ogura, Tomo Takabe, Yoei Miyabe, Yuko Iwabuchi, Kenichi Akiyama, Masayo Sato, Takahito Moriyama, Keiko Uchida, Kosaku Nitta
Summary: This case study describes a patient with SLE who progressed to end-stage renal disease (ESRD) and received belimumab treatment for lupus nephritis. The results suggest that ESRD patients may benefit from belimumab therapy, but caution is needed for potential adverse effects during treatment with belimumab.
BLOOD PURIFICATION
(2022)
Article
Biochemistry & Molecular Biology
Jose C. de la Flor, Daniel Villa, Leonidas Cruzado, Jacqueline Apaza, Francisco Valga, Rocio Zamora, Alexander Marschall, Michael Cieza, Javier Deira, Miguel Rodeles
Summary: This study retrospectively describes the safety and efficacy of SGLT2i in preserving residual kidney function (RKF) in diabetic patients undergoing incremental hemodialysis (iHD). The results showed that all patients preserved RKF after the introduction of SGLT2i and there was a significant improvement in residual kidney urea clearance (KrU) at 12 months. There were also significant improvements in blood pressure, uric acid levels, hemoglobin A1c, urine albumin/creatinine ratio (UACR), and 24-hour proteinuria. The use of SGLT2i in diabetic patients starting iHD appears to be safe and effective in preserving RKF.
Article
Cardiac & Cardiovascular Systems
Scott M. Grundy, Gloria L. Vega, Nathan D. Wong
Summary: Randomized clinical trials have demonstrated that statin therapy effectively reduces the risk of recurrent atherosclerotic cardiovascular disease in patients with established atherosclerotic disease. Therefore, high-intensity statins are universally recommended for patients with atherosclerotic cardiovascular disease, regardless of diabetes status.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Article
Multidisciplinary Sciences
Risako Mikami, Koji Mizutani, Yusuke Matsuyama, Tomohito Gohda, Hiromichi Gotoh, Norio Aoyama, Takanori Matsuura, Daisuke Kido, Kohei Takeda, Natsumi Saito, Takeo Fujiwara, Yuichi Izumi, Takanori Iwata
Summary: This study investigates the influence of type 2 diabetes mellitus (T2D) and its control level on periodontal disease and the number of missing teeth in patients undergoing hemodialysis. The results showed that T2D was significantly associated with periodontitis and the number of missing teeth in hemodialysis patients. Additionally, it was found that poor glycemic control, as determined by glycoalbumin levels, was significantly associated with the number of missing teeth in these patients.
Article
Multidisciplinary Sciences
Jihane Asmar, Dania Chelala, Razane El Hajj Chehade, Hiba Azar, Serge Finianos, Mabel Aoun
Summary: This study aims to investigate the impact of hemoglobin and iron parameters on mortality in hemodialysis patients with or without diabetes. The results showed that hemoglobin level is associated with better survival in hemodialysis patients without diabetes, but not in those with diabetes.
