GUIDES: sgRNA design for loss-of-function screens

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

(2016) John G Doench et al.   NATURE BIOTECHNOLOGY

GenomeCRISPR - a database for high-throughput CRISPR/Cas9 screens

(2016) Benedikt Rauscher et al.   NUCLEIC ACIDS RESEARCH

Alternative Splicing Shapes the Phenotype of a Mutation inBBS8To Cause Nonsyndromic Retinitis Pigmentosa

(2015) Daniel Murphy et al.   MOLECULAR AND CELLULAR BIOLOGY

Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains

(2015) Junwei Shi et al.   NATURE BIOTECHNOLOGY

High-throughput functional genomics using CRISPR–Cas9

(2015) Ophir Shalem et al.   NATURE REVIEWS GENETICS

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Organizing Principles of Mammalian Nonsense-Mediated mRNA Decay

(2013) Maximilian Wei-Lin Popp et al.   Annual Review of Genetics

The challenge of increasing Pfam coverage of the human proteome

(2013) Jaina Mistry et al.   Database-The Journal of Biological Databases and Curation