Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease
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Title
Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease
Authors
Keywords
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Journal
NATURE MATERIALS
Volume 16, Issue 11, Pages 1112-1119
Publisher
Springer Nature
Online
2017-10-02
DOI
10.1038/nmat4994
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Note: Only part of the references are listed.- Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner
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- The Molecular Signatures Database Hallmark Gene Set Collection
- (2015) Arthur Liberzon et al. Cell Systems
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- (2014) Yiqiang Cai et al. JOURNAL OF CLINICAL INVESTIGATION
- Redefining the In Vivo Origin of Metanephric Nephron Progenitors Enables Generation of Complex Kidney Structures from Pluripotent Stem Cells
- (2013) Atsuhiro Taguchi et al. Cell Stem Cell
- Reduced Ciliary Polycystin-2 in Induced Pluripotent Stem Cells from Polycystic Kidney Disease Patients with PKD1 Mutations
- (2013) B. S. Freedman et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
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- The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formation
- (2010) S. Mangos et al. Disease Models & Mechanisms
- Incompletely Penetrant PKD1 Alleles Mimic the Renal Manifestations of ARPKD
- (2010) M. Vujic et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Renal injury is a third hit promoting rapid development of adult polycystic kidney disease
- (2009) Ayumi Takakura et al. HUMAN MOLECULAR GENETICS
- Systems biology of autosomal dominant polycystic kidney disease (ADPKD): computational identification of gene expression pathways and integrated regulatory networks
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- Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia
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