Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers

(2016) Christopher I. Amos et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The β2-adrenoceptor activates a positive cAMP-calcium feedforward loop to drive breast cancer cell invasion

(2016) Cindy K. Pon et al.   FASEB JOURNAL

An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression

(2016) Asaf Wyszynski et al.   HUMAN MOLECULAR GENETICS

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170

(2016) Alison M Dunning et al.   NATURE GENETICS

F-BOX proteins in cancer cachexia and muscle wasting: Emerging regulators and therapeutic opportunities

(2016) Ammar Sukari et al.   SEMINARS IN CANCER BIOLOGY

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

(2016) Fergus J. Couch et al.   Nature Communications

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus

(2016) Kate Lawrenson et al.   Nature Communications

Fine-Scale Mapping of the 5q11.2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K1

(2015) Dylan M. Glubb et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression

(2015) Hatef Darabi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2

(2015) N. Orr et al.   HUMAN MOLECULAR GENETICS

Interaction of Heat Shock Protein Cpn10 with the Cyclin E/Cdk2 Substrate Nuclear Protein Ataxia-Telangiectasia (NPAT) Is Involved in Regulating Histone Transcription

(2015) Li Ling Zheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

(2015) Nasim Mavaddat et al.   JNCI-Journal of the National Cancer Institute

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

(2015) Kyriaki Michailidou et al.   NATURE GENETICS

Partitioning heritability by functional annotation using genome-wide association summary statistics

(2015) Hilary K Finucane et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Gene-Panel Sequencing and the Prediction of Breast-Cancer Risk

(2015) Douglas F. Easton et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

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Cyclin E2 is the predominant E-cyclin associated with NPAT in breast cancer cells

(2015) Samuel Rogers et al.   Cell Division

Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

(2015) Nasim Mavaddat et al.   JNCI-Journal of the National Cancer Institute

A Genome-wide Association Study of Early-Onset Breast Cancer Identifies PFKM as a Novel Breast Cancer Gene and Supports a Common Genetic Spectrum for Breast Cancer at Any Age

(2014) H. Ahsan et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

(2014) Suhas S.P. Rao et al.   CELL

Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium

(2014) Roger L. Milne et al.   HUMAN MOLECULAR GENETICS

A promoter-level mammalian expression atlas

(2014)   NATURE

Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1

(2014) Qiuyin Cai et al.   NATURE GENETICS

Global view of enhancer-promoter interactome in human cells

(2014) B. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation

(2014) Maya Ghoussaini et al.   Nature Communications

Functional Variants at the 11q13 Risk Locus for Breast Cancer Regulate Cyclin D1 Expression through Long-Range Enhancers

(2013) Juliet D. French et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Fine-Scale Mapping of the FGFR2 Breast Cancer Risk Locus: Putative Functional Variants Differentially Bind FOXA1 and E2F1

(2013) Kerstin B. Meyer et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Super-Enhancers in the Control of Cell Identity and Disease

(2013) Denes Hnisz et al.   CELL

Integrative eQTL-Based Analyses Reveal the Biology of Breast Cancer Risk Loci

(2013) Qiyuan Li et al.   CELL

Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits

(2013) O. Corradin et al.   GENOME RESEARCH

Small-Molecule Ligands of Methyl-Lysine Binding Proteins: Optimization of Selectivity for L3MBTL3

(2013) Lindsey I. James et al.   JOURNAL OF MEDICINAL CHEMISTRY

Genome-wide association studies identify four ER negative–specific breast cancer risk loci

(2013) Montserrat Garcia-Closas et al.   NATURE GENETICS

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

(2013) Stig E Bojesen et al.   NATURE GENETICS

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

(2013) Kyriaki Michailidou et al.   NATURE GENETICS

Systematic identification of trans eQTLs as putative drivers of known disease associations

(2013) Harm-Jan Westra et al.   NATURE GENETICS

Systematic discovery and characterization of regulatory motifs in ENCODE TF binding experiments

(2013) P. Kheradpour et al.   NUCLEIC ACIDS RESEARCH

Identification of a BRCA2-Specific Modifier Locus at 6p24 Related to Breast Cancer Risk

(2013) Mia M. Gaudet et al.   PLoS Genetics

Matrix eQTL: ultra fast eQTL analysis via large matrix operations

(2012) A. A. Shabalin   BIOINFORMATICS

Fast and accurate inference of local ancestry in Latino populations

(2012) Yael Baran et al.   BIOINFORMATICS

Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

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19p13.1 Is a Triple-Negative-Specific Breast Cancer Susceptibility Locus

(2012) K. N. Stevens et al.   CANCER RESEARCH

Evaluation of Association Methods for Analysing Modifiers of Disease Risk in Carriers of High-Risk Mutations

(2012) Daniel R. Barnes et al.   GENETIC EPIDEMIOLOGY

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11

(2012) Afshan Siddiq et al.   HUMAN MOLECULAR GENETICS

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Bayesian refinement of association signals for 14 loci in 3 common diseases

(2012) Julian B Maller et al.   NATURE GENETICS

Genome-wide association analysis identifies three new breast cancer susceptibility loci

(2012) Maya Ghoussaini et al.   NATURE GENETICS

Fast and accurate genotype imputation in genome-wide association studies through pre-phasing

(2012) Bryan Howie et al.   NATURE GENETICS

Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

(2012) Rebecca Hein et al.   PLoS One

Genome-Wide Association Study in East Asians Identifies Novel Susceptibility Loci for Breast Cancer

(2012) Jirong Long et al.   PLoS Genetics

Genetic modifiers of cancer risk for BRCA1 and BRCA2 mutation carriers

(2011) R. L. Milne et al.   ANNALS OF ONCOLOGY

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Gene set analysis of genome-wide association studies: Methodological issues and perspectives

(2011) Lily Wang et al.   GENOMICS

Genome-wide association study identifies breast cancer risk variant at 10q21.2: results from the Asia Breast Cancer Consortium

(2011) Q. Cai et al.   HUMAN MOLECULAR GENETICS

Beta-Blocker Use Is Associated With Improved Relapse-Free Survival in Patients With Triple-Negative Breast Cancer

(2011) Amal Melhem-Bertrandt et al.   JOURNAL OF CLINICAL ONCOLOGY

Novel Breast Cancer Susceptibility Locus at 9q31.2: Results of a Genome-Wide Association Study

(2011) Olivia Fletcher et al.   JNCI-Journal of the National Cancer Institute

A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor–negative breast cancer

(2011) Christopher A Haiman et al.   NATURE GENETICS

A linear complexity phasing method for thousands of genomes

(2011) Olivier Delaneau et al.   NATURE METHODS

A User's Guide to the Encyclopedia of DNA Elements (ENCODE)

(2011)   PLOS BIOLOGY

GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers

(2011) Craig H Mermel et al.   GENOME BIOLOGY

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

ProbABEL package for genome-wide association analysis of imputed data

(2010) Yurii S Aulchenko et al.   BMC BIOINFORMATICS

Evaluating the power to discriminate between highly correlated SNPs in genetic association studies

(2010) Miriam S. Udler et al.   GENETIC EPIDEMIOLOGY

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

(2010) Yun Li et al.   GENETIC EPIDEMIOLOGY

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population

(2010) Antonis C Antoniou et al.   NATURE GENETICS

Genome-wide association study identifies five new breast cancer susceptibility loci

(2010) Clare Turnbull et al.   NATURE GENETICS

Analysing biological pathways in genome-wide association studies

(2010) Kai Wang et al.   NATURE REVIEWS GENETICS

Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation

(2010) Daniele Merico et al.   PLoS One

A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1)

(2009) Gilles Thomas et al.   NATURE GENETICS

Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1

(2009) Wei Zheng et al.   NATURE GENETICS

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2

(2009) Shahana Ahmed et al.   NATURE GENETICS

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions

(2008) A C Antoniou et al.   BRITISH JOURNAL OF CANCER

Common variants on chromosome 5p12 confer susceptibility to estrogen receptor–positive breast cancer

(2008) Simon N Stacey et al.   NATURE GENETICS