Peptidomimetic inhibitors of APC–Asef interaction block colorectal cancer migration

The Cellular Thermal Shift Assay: A Novel Biophysical Assay for In Situ Drug Target Engagement and Mechanistic Biomarker Studies

(2016) Daniel Martinez Molina et al.   Annual Review of Pharmacology and Toxicology

CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil

(2016) Helena Almqvist et al.   Nature Communications

Loss of ZFP36 expression in colorectal cancer correlates to wnt/ β-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of ZEB1, SOX9 and MACC1

(2016) Lucia Montorsi et al.   Oncotarget

miR186 suppresses prostate cancer progression by targeting Twist1

(2016) Xian Zhao et al.   Oncotarget

Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes

(2015) Marta Pelay-Gimeno et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Peptide therapeutics: current status and future directions

(2015) Keld Fosgerau et al.   DRUG DISCOVERY TODAY

SUMOylation of TARBP2 regulates miRNA/siRNA efficiency

(2015) Cheng Chen et al.   Nature Communications

Assessing the Efficacy of Mdm2/Mdm4-Inhibiting Stapled Peptides Using Cellular Thermal Shift Assays

(2015) Ban Xiong Tan et al.   Scientific Reports

Selectivity by Small-Molecule Inhibitors of Protein Interactions Can Be Driven by Protein Surface Fluctuations

(2015) David K. Johnson et al.   PLoS Computational Biology

Future directions for peptide therapeutics development

(2013) Allan A. Kaspar et al.   DRUG DISCOVERY TODAY

Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay

(2013) D. M. Molina et al.   SCIENCE

MiRNA-296-3p-ICAM-1 axis promotes metastasis of prostate cancer by possible enhancing survival of natural killer cell-resistant circulating tumour cells

(2013) X Liu et al.   Cell Death & Disease

RhoGDI SUMOylation at Lys-138 Increases Its Binding Activity to Rho GTPase and Its Inhibiting Cancer Cell Motility

(2012) Jianxiu Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for the recognition of Asef by adenomatous polyposis coli

(2011) Zhenyi Zhang et al.   CELL RESEARCH

Directed cell invasion and migration during metastasis

(2011) Jose Javier Bravo-Cordero et al.   CURRENT OPINION IN CELL BIOLOGY

Impedance measurement for real time detection of neuronal cell death

(2011) S. Diemert et al.   JOURNAL OF NEUROSCIENCE METHODS

Crystal Structures of the Armadillo Repeat Domain of Adenomatous Polyposis Coli and Its Complex with the Tyrosine-Rich Domain of Sam68

(2011) Ella Czarina Morishita et al.   STRUCTURE

RAGE-TXNIP axis is required for S100B-promoted Schwann cell migration, fibronectin expression and cytokine secretion

(2010) O. Sbai et al.   JOURNAL OF CELL SCIENCE

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

The adenomatous polyposis coli-associated exchange factors Asef and Asef2 are required for adenoma formation in ApcMin/+mice

(2009) Yoshihiro Kawasaki et al.   EMBO REPORTS

The Adenomatous Polyposis Coli-associated Guanine Nucleotide Exchange Factor Asef Is Involved in Angiogenesis

(2009) Yoshihiro Kawasaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The armadillo repeat domain of the APC tumor suppressor protein interacts with Striatin family members

(2008) Maya Breitman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH