A Platform for Analysis of Nanoscale Liquids with an Array of Sensor Devices Based on Two-Dimensional Material

Analysis of nanoscale liquids, including wetting and flow phenomena, is a scientific challenge-with far reaching implications :for-industrial technologies. We report the conception; development, and application of an integrated platform for the experimental characterization of liquids at the nanometer scale. The platform combines the functionalities of a two-dimensional electronic array of sensor devices with in situ application of highly sensitive optical microspectroscopy and atomic force microscopy. We demonstrate the performance,capabilities of the platform with an embodiment based on an array of optically transparent graphene sensors., The application of electronic, and optical sensing in the platform allows for differentiating between liquids electronically, for determining a liquid's molecular fingerprint, and for monitoring surface wetting, dynamics in real time. In order to, explore the: platform's sensitivity limits, we record topographies and optical spectra of. individual, spatially isolated sessile oil emulsion droplets having volumes of less than ten attoliters. The results,:clemonstraterthat, integrated measurement functionalities based on two-Amensional materials have the potential to push lab-on-chip based-analysii from the microscale to the nanoscale.