4.4 Article

New device for nonvolitional evaluation of quadriceps force in ventilated patients

Journal

MUSCLE & NERVE
Volume 57, Issue 5, Pages 784-791

Publisher

WILEY
DOI: 10.1002/mus.26026

Keywords

femoral nerve; ICU; magnetic stimulation; mechanical ventilation; nonvolitional strength; quadriceps; strength; weakness

Funding

  1. Veterans Administration Research Service

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IntroductionIn mechanically ventilated patients, nonvolitional assessment of quadriceps weakness using femoral-nerve stimulation (twitch force) while the leg rests on a right-angle trapezoid or dangles from the bed edge is impractical. Accordingly, we developed a knee-support apparatus for use in ventilated patients. MethodsNinety subjects (12 ventilated patients, 28 ambulatory patients, and 50 healthy subjects) were enrolled. Twitches with leg-dangling, trapezoid, and knee-support setups were compared. ResultsKnee-support twitches were similar to trapezoid twitches but smaller than leg-dangling twitches (P<0.0001). Inter- and intraoperator agreement was high for knee-support twitches at 1 week and 1 month. In ventilated patients, knee-support twitches were smaller than in healthy subjects and ambulatory patients (P<0.004). DiscussionThe new knee-support apparatus allows accurate recording of quadriceps twitches. The ease of use in ventilated patients and excellent inter- and intraoperator agreement suggest that this technique is suitable for cross-sectional and longitudinal studies in critically ill patients. Muscle Nerve57: 784-791, 2018

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