Article
Medicine, General & Internal
Vanessa Wellauer, Julia F. Item, Mario Bizzini, Nicola A. Maffiuletti
Summary: This study compared the effectiveness of a home-based NMES program to a sham-NMES program in patients following ACL reconstruction. The results showed that a 6-week home-based NMES program applied to the quadriceps of the nonoperative side prevented knee extensor muscle weakness 6 months after surgery.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Yuta Takahashi, Tomoyuki Morisawa, Hiroshi Okamoto, Nobuto Nakanishi, Noriko Matsumoto, Masakazu Saitoh, Tetsuya Takahashi, Toshiyuki Fujiwara
Summary: This study compared the incidence of diaphragm dysfunction and ICU-acquired weakness in patients with septic shock, with and without mechanical ventilation. The incidence of diaphragm dysfunction was higher than that of ICU-acquired weakness in patients with septic shock, regardless of the use of mechanical ventilation. Further studies are needed to assess the association between diaphragm dysfunction and clinical outcomes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Letter
Medicine, General & Internal
E. Wesley Ely
Summary: Previous investigations have shown that oversedation and immobilization of mechanically ventilated patients are associated with or result in greater length of hospital stay, decreased survival, and greater incidence of acquired dementia. The evidence-based ABCDEF safety bundle helps us rehumanize care and establish higher adherence to key steps; E (for early mobility) yields dose-response results of earlier discharge and greater survival.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Anesthesiology
Clement Medrinal, Guillaume Prieur, Tristan Bonnevie, Francis-Edouard Gravier, Denys Mayard, Emmanuelle Desmalles, Pauline Smondack, Bouchra Lamia, Yann Combret, Guillaume Fossat
Summary: The majority of COVID-19 ICU survivors experienced acquired limb muscle weakness. One-fourth of patients had both limb and respiratory muscle weakness. 44% of patients with limb weakness still had severely limited function in walking one month post weaning.
BMC ANESTHESIOLOGY
(2021)
Article
Clinical Neurology
Colin W. McInnes, Austin Y. Ha, Hollie A. Power, Thomas H. Tung, Amy M. Moore
Summary: Femoral nerve decompression and nerve transfer using sartorius branches are effective in restoring function in partial femoral nerve injuries. Sartorius branches are ideal donors for quadriceps nerve transfers due to their proximity, expendability, and adequate nerve fiber supply. Improved knee extension and decreased pain scores were observed postoperatively in patients who underwent these procedures.
JOURNAL OF NEUROSURGERY
(2021)
Article
Multidisciplinary Sciences
Arnhold Lohse, Philip von Platen, Carl-Friedrich Benner, Matthias Manfred Deininger, Teresa Gertrud Seemann, Dmitrij Ziles, Thomas Breuer, Steffen Leonhardt, Marian Walter
Summary: Diaphragm atrophy is a common issue in mechanically ventilated patients, but electric phrenic nerve stimulation may help avoid it. However, the optimal stimulation parameters for sufficient ventilation need further investigation. A prototype system was evaluated, and the main indicator for efficient stimulation was found to be the tidal volume. The results provide a guideline for setting stimulation parameters and have implications for future clinical applications.
SCIENTIFIC REPORTS
(2023)
Article
Orthopedics
Tao Zhang, Tingting Zhang, Xiaoyin Niu, Lantao Li, Jiaji Gu, Minghui Chen, Xuan Zhao
Summary: The study found that compared to 0.2% ropivacaine, 0.1% ropivacaine preserved quadriceps strength at 6 h after knee arthroscopy while providing similar analgesic effects.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2023)
Article
Nursing
Sahar Younes Othman, Maysa Abdalla Elbiaa, Eman R. Mansour, Ahmed M. El-Menshawy, Shimmaa Mohamed Elsayed
Summary: The study aimed to evaluate the effect of NMES and early physical activity on ICU-AW in mechanically ventilated patients. The results showed that daily sessions of NMES and early physical activity were well tolerated, preserved muscle strength, prevented ICU-AW, and decreased the duration of the MV and ICU stay.
NURSING IN CRITICAL CARE
(2023)
Article
Respiratory System
Kyle G. P. J. M. Boyle, Philipp A. Eichenberger, Patrick Schoen, Christina M. Spengler
Summary: Rapid magnetic stimulation can attenuate diaphragm atrophy during mechanical ventilation. This study compared the effectiveness and side effects of three different magnetic stimulation coils when used on the neck or chest, and found that RMSBAMPS was more effective than RMSaMS in temporarily ventilating humans.
RESPIRATORY RESEARCH
(2022)
Article
Respiratory System
Come Bureau, Marine Van Hollebeke, Martin Dres
Summary: Weaning is a critical stage in ICU care and respiratory muscles play a major role. Weakness of respiratory muscles, including diaphragm atrophy and dysfunction, as well as extradiaphragmatic inspiratory and expiratory muscles, is associated with significant morbidity in the ICU. Diagnosis of respiratory muscle weakness can be visually suspected through paradoxical movement of the abdominal compartment or measured using maximal inspiratory pressure. However, ultrasound may be a better option for assessing respiratory muscle function in the ICU. It is important to not let diaphragm dysfunction discourage clinicians from performing spontaneous breathing trials and considering extubation, as recent therapeutic developments show promise in preserving or restoring respiratory muscle function.
EUROPEAN RESPIRATORY REVIEW
(2023)
Article
Respiratory System
Caroline Attwell, Laurent Sauterel, Jane Joehr, Lise Piquilloud, Thierry Kuntzer, Karin Diserens
Summary: This study aims to assess the feasibility of early detection of Critical Illness Polyneuropathy (CIP) and Myopathy (CIM) in patients with septic shock and prolonged mechanical ventilation through peroneal nerve test (PENT) and sensory sural nerve action potential (SNAP) screening. The results showed that CIP and CIM are common in septic shock patients and can be detected before becoming symptomatic with simple bedside tools.
BMC PULMONARY MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Marloes van den Berg, Eva L. Peters, Robbert J. van der Pijl, Shengyi Shen, Leo M. A. Heunks, Henk L. Granzier, Coen A. C. Ottenheijm
Summary: Diaphragm weakness frequently occurs in mechanically ventilated critically ill patients, and this study suggests that modulating titin stiffness may affect its development.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Cardiac & Cardiovascular Systems
Jaber S. Alqahtani, Mohammed D. Alahamri, Abdullah S. Alqahtani, Asma O. Alamoudi, Nawal Z. Alotaibi, Abdullah A. Ghazwani, Abdulelah M. Aldhahir, Saeed M. Alghamdi, Afrah Obaidan, Asma Falah Alharbi, Jithin K. Sreedharan, Saad M. Al Rabeeah, Eidan M. Al Zahrani
Summary: This study investigated the practices and barriers of early mobilization for mechanically ventilated patients in Saudi Arabian ICUs. The prevalence of early mobilization was found to be 47%, while only 36% of the ICU staff had received previous training. Lack of training, guidelines, and staffing were identified as the main barriers to promoting early mobilization.
Article
Respiratory System
Michal Sotak, Karel Roubik, Tomas Henlin, Tomas Tyll
Summary: Phrenic nerve stimulation can effectively prevent diaphragm atrophy, increase diaphragm thickness, and improve muscle strength required for spontaneous ventilation.
BMC PULMONARY MEDICINE
(2021)
Article
Orthopedics
Abigail R. Frazer, Marie-Eve Chausse, Marlee Held, Catherine St-Pierre, Cheng Yi Tsai, Richard Preuss, Nancy Descoteaux, Monica Chan, Paul A. Martineau, Louis-Nicolas Veilleux
Summary: This study compared isokinetic strength recovery in adolescents who received FNB, ACB, or no block for pain control during ACL reconstruction. The results showed minimal difference in quadriceps strength among the three groups approximately 6 months postoperatively, with the only significant strength deficit observed in the hamstrings of patients receiving ACB at peak flexion compared with those receiving FNB.
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2021)