A Network-Based Pharmacology Study of the Herb-Induced Liver Injury Potential of Traditional Hepatoprotective Chinese Herbal Medicines

Estrogen Signals Through Peroxisome Proliferator-Activated Receptor−γ Coactivator 1α to Reduce Oxidative Damage Associated With Diet-Induced Fatty Liver Disease

(2017) Aurèle Besse-Patin et al.   GASTROENTEROLOGY

Systems pharmacology – Towards the modeling of network interactions

(2016) Meindert Danhof   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Toxicological role of an acyl glucuronide metabolite in diclofenac-induced acute liver injury in mice

(2016) Shingo Oda et al.   JOURNAL OF APPLIED TOXICOLOGY

Nuclear factor kappa B activation and peroxisome proliferator-activated receptor transactivational effects of chemical components of the roots of Polygonum multiflorum

(2016) YoungHo Kim et al.   Pharmacognosy Magazine

Comparison of the inhibitory effects of tolcapone and entacapone against human UDP-glucuronosyltransferases

(2016) Xia Lv et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Network pharmacology-based identification of key pharmacological pathways of Yin–Huang–Qing–Fei capsule acting on chronic bronchitis

(2016) Guohua Yu et al.   International Journal of Chronic Obstructive Pulmonary Disease

A network pharmacology approach reveals new candidate caloric restriction mimetics inC. elegans

(2015) Shaun Calvert et al.   AGING CELL

In silico database screening of potential targets and pathways of compounds contained in plants used for psoriasis vulgaris

(2015) Brian H. May et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Dissecting stromal-epithelial interactions in a 3D in vitro cellularized intestinal model for permeability studies

(2015) Carla Pereira et al.   BIOMATERIALS

Activation of the Mitochondrial Apoptotic Pathway Produces Reactive Oxygen Species and Oxidative Damage in Hepatocytes That Contribute to Liver Tumorigenesis

(2015) H. Hikita et al.   Cancer Prevention Research

UDP-glucuronosyltransferase (UGT) 1A1 mainly contributes to the glucuronidation of trovafloxacin

(2015) Ryoichi Fujiwara et al.   Drug Metabolism and Pharmacokinetics

Liver Damage Associated withPolygonum multiflorumThunb.: A Systematic Review of Case Reports and Case Series

(2015) Xiang Lei et al.   Evidence-based Complementary and Alternative Medicine

Traditional usages, botany, phytochemistry, pharmacology and toxicology of Polygonum multiflorum Thunb.: A review

(2015) Longfei Lin et al.   JOURNAL OF ETHNOPHARMACOLOGY

Adjunctive traditional Chinese medicine therapy improves survival of liver cancer patients

(2015) Yueh-Hsiang Liao et al.   LIVER INTERNATIONAL

Glycyrrhizic acid inhibits apoptosis and fibrosis in carbon-tetrachloride-induced rat liver injury

(2015) Bo Liang   WORLD JOURNAL OF GASTROENTEROLOGY

Cobalt protoporphyrin protects the liver against apoptosis in rats of brain death

(2015) Hongbo Fang et al.   Clinics and Research in Hepatology and Gastroenterology

A Knowledge-Based Approach for Identification of Drugs Against Vivapain-2 Protein of Plasmodium vivax Through Pharmacophore-Based Virtual Screening with Comparative Modelling

(2014) Manoj Kumar Yadav et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

A Network Pharmacology Study of Chinese Medicine QiShenYiQi to Reveal Its Underlying Multi-Compound, Multi-Target, Multi-Pathway Mode of Action

(2014) Xiang Li et al.   PLoS One

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

(2014) Jinlong Ru et al.   Journal of Cheminformatics

Anti-fibrotic effect of Cordyceps sinensis polysaccharide: Inhibiting HSC activation, TGF-β1/Smad signalling, MMPs and TIMPs

(2013) Jinghua Peng et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Systems pharmacology uncovers Janus functions of botanical drugs: activation of host defense system and inhibition of influenza virus replication

(2012) Xia Wang et al.   Integrative Biology

Genetic Variation in the Peroxisome Proliferator Activated Receptor-Gamma Gene Is Associated with Histologically Advanced NAFLD

(2011) Samer Gawrieh et al.   DIGESTIVE DISEASES AND SCIENCES

Toxicity of raw and processed roots of Polygonum multiflorum

(2011) Xiaoqing Wu et al.   FITOTERAPIA

Drug-Induced Liver Injury: Twenty Five Cases of Acute Hepatitis Following Ingestion of Polygonum multiflorum Thunb

(2011) Kyoung Ah Jung et al.   Gut and Liver

A single arm phase II study of a Far-Eastern traditional herbal formulation (sho-sai-ko-to or xiao-chai-hu-tang) in chronic hepatitis C patients

(2011) Gary Deng et al.   JOURNAL OF ETHNOPHARMACOLOGY

ADME Evaluation in Drug Discovery. 9. Prediction of Oral Bioavailability in Humans Based on Molecular Properties and Structural Fingerprints

(2011) Sheng Tian et al.   MOLECULAR PHARMACEUTICS

Hepatoprotection of emodin andPolygonum multiflorumagainst CCl4-induced liver injury

(2011) Bao-Hong Lee et al.   PHARMACEUTICAL BIOLOGY

The Pharmacokinetics of Silymarin Is Altered in Patients with Hepatitis C Virus and Nonalcoholic Fatty Liver Disease and Correlates with Plasma Caspase-3/7 Activity

(2008) S. J. Schrieber et al.   DRUG METABOLISM AND DISPOSITION

Knockout of myeloid cell leukemia-1 induces liver damage and increases apoptosis susceptibility of murine hepatocytes

(2008) Binje Vick et al.   HEPATOLOGY