Review
Biochemistry & Molecular Biology
Kamila Kasprzak-Drozd, Tomasz Oniszczuk, Mateusz Stasiak, Anna Oniszczuk
Summary: The human intestine contains a complex community of microorganisms known as the gut microbiota, which plays a crucial role in maintaining host homeostasis. Dietary polyphenols have been investigated for their beneficial effects in preventing metabolic diseases and their modulation of the gut microbiota. The interdependence between gut microbiota and polyphenol metabolites in maintaining host gut homeostasis is also emphasized.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Peripheral Vascular Disease
David L. Mattson, John Henry Dasinger, Justine M. Abais-Battad
Summary: Salt-sensitive hypertension in patients with high blood pressure is associated with higher morbidity, mortality, and renal damage compared to those with normal blood pressure or salt-resistant hypertension. Dietary components other than salt play a role in modulating hypertension, and immunity and inflammation are key factors that amplify the development of salt-sensitive hypertension.
Review
Chemistry, Medicinal
Azar Hosseini, Bibi Marjan Razavi, Maciej Banach, Hossein Hosseinzadeh
Summary: Quercetin, as an important flavonoid, has potential effects in improving symptoms of metabolic syndrome, but further research and clinical trials are needed to determine its true clinical value.
PHYTOTHERAPY RESEARCH
(2021)
Article
Agriculture, Multidisciplinary
Shishi Huang, Yuan Zou, Hongbiao Tang, Jingyu Zhuang, Zhiwei Ye, Tao Wei, Junfang Lin, Qianwang Zheng
Summary: This study found that Cordyceps militaris polysaccharides (CMP) can significantly reduce obesity induced by a high-fat diet, improve hyperlipidemia and insulin resistance, and alleviate systemic inflammation. Additionally, CMP can regulate obesity-induced gut dysbiosis by restoring the diversity of gut microbiota and increasing the abundance of short-chain fatty acid-producing bacteria. This study highlights the potential of CMP as a prebiotic agent to protect obese individuals from metabolic disorders and gut dysbiosis.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Nutrition & Dietetics
Hwan-Hee Jang, Hwayoung Noh, Gichang Kim, Su-Yeon Cho, Hyeon-Jeong Kim, Jeong-Sook Choe, Jeongseon Kim, Augustin Scalbert, Marc J. Gunter, Oran Kwon, Hyesook Kim
Summary: Diet plays a significant role in the progression of metabolic syndrome into various diseases. The gut microbiota can modulate the impact of diet on metabolic health. Different gut microbial enterotypes are associated with distinct dietary patterns related to MetS, indicating the potential for personalized nutrition guidelines to prevent MetS.
FRONTIERS IN NUTRITION
(2023)
Review
Food Science & Technology
Soheila Abachi, Genevieve Pilon, Andre Marette, Laurent Bazinet, Lucie Beaulieu
Summary: This article focuses on recent studies on hypoglycemic, lipid-lowering, cholesterol-lowering, and anti-obesity fish peptides. The aim is to provide more knowledge for the design and discovery of anti-MetS compounds by comparing different extraction, isolation, and purification methods.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Geriatrics & Gerontology
Chaojun Yang, Xiaocan Jia, Yuping Wang, Jingwen Fan, Chenyu Zhao, Yongli Yang, Xuezhong Shi
Summary: This study examines the prevalence, intervention, and control of metabolic syndrome (MetS) among US adults from 1999 to 2018, finding a significant increase in MetS prevalence during this time period. Factors such as smoking and vigorous activity were found to influence MetS prevalence. Elevated blood glucose and obesity were identified as the main causes of MetS burden. The study suggests that targeting specific populations for treatment and lifestyle modification could improve the control of blood glucose and obesity.
Article
Endocrinology & Metabolism
Ekaterina A. Dobreva, Anna M. Gorbacheva, Ekaterina E. Bibik, Anna K. Eremkina, Alina R. Elfimova, Rustam Kh. Salimkhanov, Elena V. Kovaleva, Irina S. Maganeva, Natalia G. Mokrysheva
Summary: This study revealed a high incidence of cardiovascular diseases and metabolic disorders in patients with PHPT, with obesity and type 2 diabetes being more common in older patients. Older patients also showed a higher prevalence of conditions such as hypertension, ischemic heart disease, and chronic heart failure. Age above 56 years, eGFR below 92 ml/min/1.73m2, BMI above 28.3 kg/m2 were identified as significant risk factors for detecting CVD.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Microbiology
Agnieszka Zawada, Anna Maria Rychter, Alicja Ewa Ratajczak, Agata Lisiecka-Masian, Agnieszka Dobrowolska, Iwona Krela-Kazmierczak
Summary: Recent research has been focusing on the role of gut microbiota in the development or course of various diseases, including non-communicable diseases. It remains challenging to determine whether certain microbial imbalances are detrimental or beneficial. Dietary patterns and nutrients play a significant role in shaping the intestinal microbiota.
Article
Genetics & Heredity
Malihe Aghasizadeh, Reza Zare-Feyzabadi, Tooba Kazemi, Amir Avan, Gordon A. Ferns, Habibollah Esmaily, Ebrahim Miri-Moghaddam, Majid Ghayour-Mobarhan
Summary: This study aimed to investigate the association between three variants of the ANGPTL3 gene and cardiovascular disease risk factors, with findings indicating that the GTC and CTC haplotypes may help identify individuals with a genetic susceptibility to cardiometabolic disorders.
Review
Chemistry, Medicinal
Nahid Najafi, Soghra Mehri, Mahboobeh Ghasemzadeh Rahbardar, Hossein Hosseinzadeh
Summary: This study discusses the effects of alpha-lipoic acid (alpha-LA) on different components of metabolic syndrome (MetS) and the underlying molecular mechanisms. Alpha-LA has various pharmacological effects, including antidiabetic, antiobesity, hypotensive, and hypolipidemic actions. It can improve the components of MetS, reduce cholesterol biosynthesis and atherosclerosis, and increase insulin secretion and sensitivity.
PHYTOTHERAPY RESEARCH
(2022)
Article
Health Care Sciences & Services
Vanessa Stadlbauer
Summary: The association between shifts in gut microbiome composition and metabolic disorders is well-established. Fecal microbiome transplantation (FMT) has been used to alter microbiome composition to treat metabolic diseases. However, FMT is not widely applicable due to its resource-intensiveness, procedural risks, and inconsistent effects. This review highlights the current knowledge on FMT and emphasizes the need for further research to develop less resource-intensive methods with predictable outcomes, such as encapsulated formulations, as well as commitment from all stakeholders to explore live microbial agents, next-generation probiotics, and targeted dietary interventions.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Oncology
Gang Won Choi, Hyeon-Kyoung Cheong, Soo Young Choi, Young Chan Lee, In-Hwan Oh, Young-Gyu Eun
Summary: This study found a significant association between metabolic syndrome and oral cavity cancer, especially in males and young males under the age of 50. The risk of oral cavity cancer increased with an increasing number of metabolic syndrome factors.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Review
Nutrition & Dietetics
Ewa Olechno, Anna Puscion-Jakubik, Malgorzata Elzbieta Zujko
Summary: Chokeberry has positive effects on various metabolic parameters such as dyslipidemia and hypertension, increasing antioxidant defense mechanisms and potentially reducing the risk of metabolic disorders.
Article
Nutrition & Dietetics
Serena Galie, Christopher Papandreou, Pierre Arcelin, David Garcia, Antoni Palau-Galindo, Laia Gutierrez-Tordera, Alex Folch, Monica Bullo
Summary: The study identified a correlated network between specific microbial genera and fecal/plasma metabolites in an adult population with metabolic syndrome, suggesting an interplay between gut microbiota and host lipid metabolism on cardiometabolic health.
Article
Nanoscience & Nanotechnology
Hea-Jong Chung, Hyeon-Jin Kim, Seong-Tshool Hong
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
(2020)
Article
Biochemistry & Molecular Biology
Gopal Panthi, Md. Mehedi Hassan, Yun-Su Kuk, Ji Yeon Kim, Hea-Jong Chung, Seong-Tshool Hong, Mira Park
Article
Immunology
Soyeon Park, Bogyo Jung, Eunsuk Kim, Seong-Tshool Hong, Hyunjin Yoon, Tae-Wook Hahn
FRONTIERS IN IMMUNOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Md Mehedi Hassan, Shirina Sharmin, Hyeon-Jin Kim, Seong-Tshool Hong
Summary: HtrA1 and HtrA2/Omi proteins have been identified as plasmin-independent and highly specific thrombolytics that can dissolve intravascular thrombi specifically without causing bleeding risk. This study provides HtrA1 and HtrA2/Omi as ideal therapeutic candidates for various thrombotic diseases without hemorrhagic complications.
CIRCULATION RESEARCH
(2021)
Article
Medicine, General & Internal
Binh Thang Tran, Nhu Hiep Pham, Thanh Xuan Nguyen, Kui Son Choi, Dae Kyung Sohn, Sun-Young Kim, Jae Kyung Suh, Thuy Duyen Nguyen, Van Sang Phan, Dinh Trung Tran, The Thanh Nguyen, Thi Thanh Binh Nguyen, Minh Tu Nguyen, Jin-Kyoung Oh
PATIENT PREFERENCE AND ADHERENCE
(2020)
Article
Environmental Sciences
Binh Thang Tran, Kui Son Choi, Thanh Xuan Nguyen, Dae Kyung Sohn, Sun-Young Kim, Jae Kyung Suh, Van Sang Phan, Huu Tri Pham, Minh Hanh Nguyen, Thanh Binh Nguyen, Huu Khoi Hoang, Thi Thanh Binh Nguyen, Minh Tu Nguyen, Jin-Kyoung Oh
Summary: The total economic cost of colorectal cancer in Vietnam is substantial, with higher medical costs for younger and advanced-stage patients. Therefore, strategies should be developed and implemented at both patient and national levels to reduce the economic burden of CRC, such as screening programs.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Health Care Sciences & Services
Hai Huu Hoang, Anh Thi Ngoc Tran, Van Hung Nguyen, Thi Thanh Binh Nguyen, Thi Anh Phuong Nguyen, Dinh Duong Le, Alfred Jatho, David Onchonga, Tuyen Van Duong, Minh Tu Nguyen, Binh Thang Tran
Summary: This study examined the prevalence of ADHD and associated risk factors among first-year pupils in an urban city in Vietnam. It found that male gender, family history of ADHD, prenatal exposure to tobacco smoke, and alcohol consumption increased the risk of ADHD. Public health programs should focus on reducing prenatal exposure to these potential risk factors.
JOURNAL OF MULTIDISCIPLINARY HEALTHCARE
(2021)
Article
Health Care Sciences & Services
Binh Thang Tran, Kui Son Choi, Dae Kyung Sohn, Sun-Young Kim, Jae Kyung Suh, Thanh Huong Tran, Thi Thanh Binh Nguyen, Jin-Kyoung Oh
Summary: This study analyzed the cost-effectiveness of a colorectal cancer screening program in Vietnam, showing that annual screening is cost-effective and robust to parameter estimates variations. The findings could potentially be used to develop a national colorectal cancer screening program.
EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH
(2021)
Article
Microbiology
Enkhchimeg Lkhagva, Hea-Jong Chung, Ji-Seon Ahn, Seong-Tshool Hong
Summary: This study compared the impact of transitioning from a meatatarian diet to a vegetarian diet and engaging in physical exercise on the composition of the gut microbiome. The results showed that physical exercise had a more significant effect on the microbiome composition than diet transition, with differences in the patterns of change and diversity.
Article
Education & Educational Research
Minh Tu Nguyen, Thanh Gia Nguyen, Tho Thi Anh Tran, Thi Thanh Nhan Nguyen, Dinh Duong Le, Thi Thanh Binh Nguyen, Huu Hai Hoang, Thi Linh Dan Ho, Binh Thang Tran
Summary: This study investigated the impact of psychological factors on academic pressure among medical students using a network analysis approach. The results showed that satisfaction with the training programme was the most important factor affecting academic pressure.
MEDICAL EDUCATION ONLINE
(2022)
Article
Microbiology
Chongkai Zhai, Ji-Seon Ahn, Md Minarul Islam, Enkhchimeg Lkhagva, Hea-Jong Chung, Seong-Tshool Hong
Summary: This study analyzes the effects of gut microbiome on host phenotype by replacing the original gut microbiome with a new one within the same individual. The results show that different gut microbiomes have different effects on weight gain, and weight gain is negatively correlated with the Firmicutes/Bacteroidetes ratio.
Article
Ophthalmology
Thi Thanh Binh Nguyen, Van Trieu Bui, Vo Phuong Thao Pham, Thi Ny Pham
Summary: The study aimed to determine the incidence and risk factors of ROP in the NICU of Hue Central Hospital, Vietnam. Results showed a significant association between ROP development and factors such as GA, birth weight, anemia, sepsis, and respiratory distress syndrome. GA <32 weeks, sepsis, and CPAP/mechanical ventilation were identified as independent risk factors for ROP development.
CLINICAL OPHTHALMOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Ji-Seon Ahn, Yu-Jin Choi, Han-Byeol Kim, Hea-Jong Chung, Seong-Tshool Hong
Summary: This study demonstrates that the gut microbiome can contribute differently to locomotion and explains the mixed results in previous research on the association between the gut microbiome and locomotion.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Mst Ismat Ara Begum, Lin Chuan, Seong-Tshool Hong, Hee-Suk Chae
Summary: Association studies have shown that miRNA expression is significantly altered in relation to diseases, including endometriosis (EMS), particularly within inflammatory pathways. This article reviews the advancements made in understanding the pathological role of miRNA in EMS and its association with EMS-associated infertility, highlighting the potential for developing miRNA-based therapeutics and diagnostic markers.
Article
Public, Environmental & Occupational Health
That Thanh Ton, Anh Thi Ngoc Tran, Ich Thanh Do, Hoa Nguyen, Thi Thanh Binh Nguyen, Minh Tu Nguyen, Van Anh Bao Ha, Anh Quoc Tran, Huu Khoi Hoang, Thang Binh Tran
EPIDEMIOLOGY AND HEALTH
(2020)
