Paeoniflorin Attenuates Cerebral Ischemia-Induced Injury by Regulating Ca2+/CaMKII/CREB Signaling Pathway

Paeoniflorin, a Monoterpene Glycoside, Protects the Brain from Cerebral Ischemic Injury via Inhibition of Apoptosis

(2015) Yuqin Zhang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Neuronal polarity: an evolutionary perspective

(2015) M. M. Rolls et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Global, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2015)   LANCET

Kukoamine B, an amide alkaloid, protects against NMDA-induced neurotoxicity and potential mechanisms in vitro

(2015) Xiao-Long Hu et al.   NEUROCHEMISTRY INTERNATIONAL

Neuroprotective effects of Gualou Guizhi decoction in vivo and in vitro

(2014) Yuqin Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effect of Gua Lou Gui Zhi decoction on focal cerebral ischemia-reperfusion injury through regulating the expression of excitatory amino acids and their receptors

(2014) XIANWEN CHEN et al.   Molecular Medicine Reports

Paeoniflorin, a monoterpene glycoside, attenuates lipopolysaccharide-induced neuronal injury and brain microglial inflammatory response

(2013) Kyong-Nyon Nam et al.   BIOTECHNOLOGY LETTERS

Protective Effect of Paeoniflorin on Aβ25–35-Induced SH-SY5Y Cell Injury by Preventing Mitochondrial Dysfunction

(2013) Ke Wang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Heart Disease and Stroke Statistics—2014 Update

(2013) Alan S. Go et al.   CIRCULATION

Gua Lou Gui Zhi decoction exerts neuroprotective effects on post-stroke spasticity via the modulation of glutamate levels and AMPA receptor expression

(2013) JIA HUANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Neuroprotective Effects of Paeoniflorin, But Not the Isomer Albiflorin, are Associated with the Suppression of Intracellular Calcium and Calcium/Calmodulin Protein Kinase II in PC12 Cells

(2013) Di Wang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Phosphatidylinositol 3 kinase/protein kinase B is responsible for the protection of paeoniflorin upon H2O2-induced neural progenitor cell injury

(2013) Y.-M. Wu et al.   NEUROSCIENCE

Original article Protective effect of paeoniflorin against glutamate-induced neurotoxicity in PC12 cells via Bcl-2/Bax signal pathway

(2012) Rong Sun et al.   FOLIA NEUROPATHOLOGICA

The Two Pathophysiologies of Focal Brain Ischemia: Implications for Translational Stroke Research

(2012) Konstantin-Alexander Hossmann   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Paeoniflorin Protects against Ischemia-Induced Brain Damages in Rats via Inhibiting MAPKs/NF-κB-Mediated Inflammatory Responses

(2012) Ruo-Bing Guo et al.   PLoS One

Ginsenoside Rd Protects Neurons Against Glutamate-Induced Excitotoxicity by Inhibiting Ca2+ Influx

(2011) Chen Zhang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Investigational Therapies for Ischemic Stroke: Neuroprotection and Neurorecovery

(2011) Preeti Sahota et al.   Neurotherapeutics

The Anti-Inflammatory Effect of Paeoniflorin on Cerebral Infarction Induced by Ischemia-Reperfusion Injury in Sprague-Dawley Rats

(2010) Nou-Ying Tang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Protective Effects of Paeoniflorin Against Glutamate-Induced Neurotoxicity in PC12 Cells via Antioxidant Mechanisms and Ca2+ Antagonism

(2010) Qing-Qiu Mao et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Paeoniflorin, a potent natural compound, protects PC12 cells from MPP+ and acidic damage via autophagic pathway

(2010) Bi-Yin Cao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials

(2010) Kennedy R Lees et al.   LANCET

Paeoniflorin protects against NMDA-induced neurotoxicity in PC12 cells via Ca2+antagonism

(2010) Qing-Qiu Mao et al.   PHYTOTHERAPY RESEARCH

NMDA-induced neuroprotection in hippocampal neurons is mediated through the protein kinase A and CREB (cAMP-response element-binding protein) pathway

(2008) E VALERA et al.   NEUROCHEMISTRY INTERNATIONAL