GADD45a Regulates Olaquindox-Induced DNA Damage and S-Phase Arrest in Human Hepatoma G2 Cells via JNK/p38 Pathways

The critical role of oxidative stress in the toxicity and metabolism of quinoxaline 1,4-di-N-oxidesin vitroandin vivo

(2016) Xu Wang et al.   DRUG METABOLISM REVIEWS

Effect of GADD45a on olaquindox-induced apoptosis in human hepatoma G2 cells: Involvement of mitochondrial dysfunction

(2016) Daowen Li et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Curcumin Ameliorates Furazolidone-Induced DNA Damage and Apoptosis in Human Hepatocyte L02 Cells by Inhibiting ROS Production and Mitochondrial Pathway

(2016) Chongshan Dai et al.   MOLECULES

Expression of Ferritin Light Chain (FTL) Is Elevated in Glioblastoma, and FTL Silencing Inhibits Glioblastoma Cell Proliferation via the GADD45/JNK Pathway

(2016) Tingfeng Wu et al.   PLoS One

Quinoxaline 1,4-di-N-Oxides: Biological Activities and Mechanisms of Actions

(2016) Guyue Cheng et al.   Frontiers in Pharmacology

Deoxidation Rates Play a Critical Role in DNA Damage Mediated by Important Synthetic Drugs, Quinoxaline 1,4-Dioxides

(2015) Xu Wang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Olaquindox induces DNA damage via the lysosomal and mitochondrial pathway involving ROS production and p53 activation in HEK293 cells

(2015) Yang Yang et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

The Effect of GADD45a on Furazolidone-Induced S-Phase Cell-Cycle Arrest in Human Hepatoma G2 Cells

(2015) Yu Sun et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Colistin-Induced Apoptosis of Neuroblastoma-2a Cells Involves the Generation of Reactive Oxygen Species, Mitochondrial Dysfunction, and Autophagy

(2015) Chongshan Dai et al.   MOLECULAR NEUROBIOLOGY

Quinocetone-induced Nrf2/HO-1 pathway suppression aggravates hepatocyte damage of Sprague–Dawley rats

(2014) Miao Yu et al.   FOOD AND CHEMICAL TOXICOLOGY

Low doses of ochratoxin A induce micronucleus formation and delay DNA repair in human lymphocytes

(2014) Cyndia A. González-Arias et al.   FOOD AND CHEMICAL TOXICOLOGY

Olaquindox-induced apoptosis is suppressed through p38 MAPK and ROS-mediated JNK pathways in HepG2 cells

(2013) Wen-xia Zhao et al.   CELL BIOLOGY AND TOXICOLOGY

Genotoxicity of quinocetone, cyadox and olaquindox in vitro and in vivo

(2013) Awais Ihsan et al.   FOOD AND CHEMICAL TOXICOLOGY

Overexpression of DOC-1R Inhibits Cell Cycle G1/S Transition by Repressing CDK2 Expression and Activation

(2013) Qi Liu et al.   International Journal of Biological Sciences

The Metabolism of Carbadox, Olaquindox, Mequindox, Quinocetone and Cyadox: An Overview

(2013) Zhao-Ying Liu et al.   Medicinal Chemistry

GADD45α Induction by Nickel Negatively Regulates JNKs/p38 Activation via Promoting PP2Cα Expression

(2013) Yonghui Yu et al.   PLoS One

DNA Damage and Oxidative Stress in Human Disease

(2013) Sharbel Weidner Maluf et al.   Biomed Research International

Zinc oxide nanoparticles induce oxidative DNA damage and ROS-triggered mitochondria mediated apoptosis in human liver cells (HepG2)

(2012) Vyom Sharma et al.   APOPTOSIS

GADD45 Proteins: Central Players in Tumorigenesis

(2012) R. E. Tamura et al.   CURRENT MOLECULAR MEDICINE

Two generation reproduction and teratogenicity studies of feeding quinocetone fed to Wistar rats

(2012) Xu Wang et al.   FOOD AND CHEMICAL TOXICOLOGY

Gadd45a and Gadd45b modulate innate immune functions of granulocytes and macrophages by differential regulation of p38 and JNK signaling

(2012) Dominic M. Salerno et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Development of Quinoxaline 1, 4-Dioxides Resistance in Escherichia coli and Molecular Change under Resistance Selection

(2012) Wentao Guo et al.   PLoS One

Preparation of Epichlorohydrine-Modified Chitosan Microsphere Functionalized Materials and Adsorption Characterization Toward Olaquindox

(2011) Longhua Xu et al.   INTERNATIONAL JOURNAL OF POLYMER ANALYSIS AND CHARACTERIZATION

Determination of marker residue of Olaquindox in fish tissue by ultra performance liquid chromatography-tandem mass spectrometry

(2011) Xiaojun Zhang et al.   JOURNAL OF SEPARATION SCIENCE

Olaquindox induces apoptosis through the mitochondrial pathway in HepG2 cells

(2011) Jiajie Zou et al.   TOXICOLOGY

Furazolidone induced oxidative DNA damage via up-regulating ROS that caused cell cycle arrest in human hepatoma G2 cells

(2010) Xi Jin et al.   TOXICOLOGY LETTERS

Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells

(2009) Ravi P. Sahu et al.   CARCINOGENESIS

Olaquindox-induced genotoxicity and oxidative DNA damage in human hepatoma G2 (HepG2) cells

(2009) Jiajie Zou et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage

(2009) Manas K. Santra et al.   NATURE

Investigation of the genotoxicity of quinocetone, carbadox and olaquindox in vitro using Vero cells

(2008) Qian Chen et al.   FOOD AND CHEMICAL TOXICOLOGY

The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells

(2008) Young-Hee Kang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Gadd45-α and Gadd45-γ utilize p38 and JNK signaling pathways to induce cell cycle G2/M arrest in Hep-G2 hepatoma cells

(2008) Na Zhu et al.   MOLECULAR BIOLOGY REPORTS