A Peptide Nucleic Acid against MicroRNA miR-145-5p Enhances the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Calu-3 Cells

Recent progress in translational cystic fibrosis research using precision medicine strategies

(2018) Deborah M. Cholon et al.   Journal of Cystic Fibrosis

Cystic fibrosis in the era of precision medicine

(2018) Shruti M. Paranjape et al.   Paediatric Respiratory Reviews

Tumor-suppressive miR-145 co-repressed by TCF4-β-catenin and PRC2 complexes forms double-negative regulation loops with its negative regulators in colorectal cancer

(2017) Wei Wang et al.   INTERNATIONAL JOURNAL OF CANCER

MiR-145 negatively regulates Warburg effect by silencing KLF4 and PTBP1 in bladder cancer cells

(2017) Koichiro Minami et al.   Oncotarget

Personalized or Precision Medicine? The Example of Cystic Fibrosis

(2017) Fernando A. L. Marson   Frontiers in Pharmacology

miR-146a, miR-155, miR-370, and miR-708 Are CFTR-Dependent, Predicted FOXO1 Regulators and Change at Onset of CFRDs

(2016) Luisa Montanini et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The characterization of the human cell line Calu-3 under different culture conditions and its use as an optimized in vitro model to investigate bronchial epithelial function

(2015) Mateja Erdani Kreft et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

TLR response pathways in NuLi-1 cells and primary human nasal epithelial cells

(2015) Clare Cooksley et al.   MOLECULAR IMMUNOLOGY

Transcription factors and miRNAs that regulate fetal to adult CFTR expression change are new targets for cystic fibrosis

(2014) V. Viart et al.   EUROPEAN RESPIRATORY JOURNAL

miR-145 sensitizes ovarian cancer cells to paclitaxel by targeting Sp1 and Cdk6

(2014) Xiaolan Zhu et al.   INTERNATIONAL JOURNAL OF CANCER

Uptake by human glioma cell lines and biological effects of a peptide-nucleic acids targeting miR-221

(2014) Eleonora Brognara et al.   JOURNAL OF NEURO-ONCOLOGY

MicroRNA silencing for cancer therapy targeted to the tumour microenvironment

(2014) Christopher J. Cheng et al.   NATURE

Post-Transcriptional Regulation of Cystic Fibrosis Transmembrane Conductance Regulator Expression and Function by MicroRNAs

(2013) Shyam Ramachandran et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Assessing the residual CFTR gene expression in human nasal epithelium cells bearing CFTR splicing mutations causing cystic fibrosis

(2013) Laia Masvidal et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The proto-oncogene ERG is a target of microRNAmiR-145in prostate cancer

(2013) Martin Hart et al.   FEBS Journal

Elevated levels of miR-145 correlate with SMAD3 down-regulation in Cystic Fibrosis patients

(2013) Francesca Megiorni et al.   Journal of Cystic Fibrosis

Regulation of Cystic Fibrosis Transmembrane Conductance Regulator by MicroRNA-145, -223, and -494 Is Altered in  F508 Cystic Fibrosis Airway Epithelium

(2013) I. K. Oglesby et al.   JOURNAL OF IMMUNOLOGY

Gene Mutation in MicroRNA Target Sites of CFTR Gene: A Novel Pathogenetic Mechanism in Cystic Fibrosis?

(2013) Felice Amato et al.   PLoS One

PNA-based microRNA inhibitors elicit anti-inflammatory effects in microglia cells

(2012) Peter N. Brown et al.   CHEMICAL COMMUNICATIONS

Peptide nucleic acids targeting miR-221 modulate p27Kip1 expression in breast cancer MDA-MB-231 cells

(2012) ELEONORA BROGNARA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

MiR-101 and miR-144 Regulate the Expression of the CFTR Chloride Channel in the Lung

(2012) Fatemat Hassan et al.   PLoS One

A microRNA network regulates expression and biosynthesis of wild-type and  F508 mutant cystic fibrosis transmembrane conductance regulator

(2012) S. Ramachandran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

microRNA regulation of expression of the cystic fibrosis transmembrane conductance regulator gene

(2011) Austin E. Gillen et al.   BIOCHEMICAL JOURNAL

Targeting microRNAs involved in human diseases: A novel approach for modification of gene expression and drug development

(2011) Roberto Gambari et al.   BIOCHEMICAL PHARMACOLOGY

Modulation of the Biological Activity of microRNA-210 with Peptide Nucleic Acids (PNAs)

(2011) Enrica Fabbri et al.   ChemMedChem

miR-155 promotes macroscopic tumor formation yet inhibits tumor dissemination from mammary fat pads to the lung by preventing EMT

(2011) X Xiang et al.   ONCOGENE

Synergistic Post-Transcriptional Regulation of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) by miR-101 and miR-494 Specific Binding

(2011) Francesca Megiorni et al.   PLoS One

Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809

(2011) F. Van Goor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miRNA therapeutics: delivery and biological activity of peptide nucleic acids targeting miRNAs

(2011) Enrica Fabbri et al.   Epigenomics

Gene Targeting and Expression Modulation by Peptide Nucleic Acids (PNA)

(2010) Peter E. Nielsen   CURRENT PHARMACEUTICAL DESIGN

Efficient inhibition of miR-155 function in vivo by peptide nucleic acids

(2010) Martin M. Fabani et al.   NUCLEIC ACIDS RESEARCH

Cystic fibrosis transmembrane conductance regulator expression in human spinal and sympathetic ganglia

(2009) Na Niu et al.   LABORATORY INVESTIGATION

Subnanomolar antisense activity of phosphonate-peptide nucleic acid (PNA) conjugates delivered by cationic lipids to HeLa cells

(2008) Takehiko Shiraishi et al.   NUCLEIC ACIDS RESEARCH