Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study
Authors
Keywords
-
Journal
MOLECULES
Volume 22, Issue 12, Pages 2098
Publisher
MDPI AG
Online
2017-11-30
DOI
10.3390/molecules22122098
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- An Unusual Dimeric Inhibitor of Acetylcholinesterase: Cooperative Binding of Crystal Violet
- (2017) Anders Allgardsson et al. MOLECULES
- Hopeahainol A binds reversibly at the acetylcholinesterase (AChE) peripheral site and inhibits enzyme activity with a novel higher order concentration dependence
- (2016) Terrone L. Rosenberry et al. CHEMICO-BIOLOGICAL INTERACTIONS
- The Nature of Activated Non-classical Hydrogen Bonds: A Case Study on Acetylcholinesterase-Ligand Complexes
- (2016) Lotta Berg et al. CHEMISTRY-A EUROPEAN JOURNAL
- Discovery and Structure–Activity Relationships of a Highly Selective Butyrylcholinesterase Inhibitor by Structure-Based Virtual Screening
- (2016) Satish N. Dighe et al. JOURNAL OF MEDICINAL CHEMISTRY
- Applications of isothermal titration calorimetry - the research and technical developments from 2011 to 2015
- (2016) Robert J. Falconer JOURNAL OF MOLECULAR RECOGNITION
- Development of an in-vivo active reversible butyrylcholinesterase inhibitor
- (2016) Urban Košak et al. Scientific Reports
- Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents
- (2015) Damijan Knez et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Discovery, Biological Evaluation, and Crystal Structure of a Novel Nanomolar Selective Butyrylcholinesterase Inhibitor
- (2014) Boris Brus et al. JOURNAL OF MEDICINAL CHEMISTRY
- Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase
- (2013) Florian Nachon et al. BIOCHEMICAL JOURNAL
- The Natural Product Dihydrotanshinone I Provides a Prototype for Uncharged Inhibitors That Bind Specifically to the Acetylcholinesterase Peripheral Site with Nanomolar Affinity
- (2013) Veena Beri et al. BIOCHEMISTRY
- Inhibition Pathways of the Potent Organophosphate CBDP with Cholinesterases Revealed by X-ray Crystallographic Snapshots and Mass Spectrometry
- (2013) Eugénie Carletti et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Probing the Peripheral Site of Human Butyrylcholinesterase
- (2012) Ian R. Macdonald et al. BIOCHEMISTRY
- A step toward the reactivation of aged cholinesterases – Crystal structure of ligands binding to aged human butyrylcholinesterase
- (2012) Marielle Wandhammer et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Human butyrylcholinesterase produced in insect cells: huprine-based affinity purification and crystal structure
- (2012) Xavier Brazzolotto et al. FEBS Journal
- Mechanism of stereoselective interaction between butyrylcholinesterase and ethopropazine enantiomers
- (2011) Goran Šinko et al. BIOCHIMIE
- Drug-like Leads for Steric Discrimination between Substrate and Inhibitors of Human Acetylcholinesterase
- (2011) Scott A. Wildman et al. Chemical Biology & Drug Design
- New Huprine Derivatives Functionalized at Position 9 as Highly Potent Acetylcholinesterase Inhibitors
- (2011) Cyril Ronco et al. ChemMedChem
- Huprine Derivatives as Sub-Nanomolar Human Acetylcholinesterase Inhibitors: From Rational Design to Validation by X-ray Crystallography
- (2011) Cyril Ronco et al. ChemMedChem
- Structural Study of the Complex Stereoselectivity of Human Butyrylcholinesterase for the Neurotoxic V-agents
- (2011) Marielle Wandhammer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- X-ray crystallographic snapshots of reaction intermediates in the G117H mutant of human butyrylcholinesterase, a nerve agent target engineered into a catalytic bioscavenger
- (2010) Florian Nachon et al. BIOCHEMICAL JOURNAL
- Differential binding of phenothiazine urea derivatives to wild-type human cholinesterases and butyrylcholinesterase mutants
- (2010) Sultan Darvesh et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Molecular basis of inhibition of substrate hydrolysis by a ligand bound to the peripheral site of acetylcholinesterase
- (2010) Jeffrey T. Auletta et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Structure–activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun
- (2009) Eugénie Carletti et al. BIOCHEMICAL JOURNAL
- AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
- (2009) Oleg Trott et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Carbamates with Differential Mechanism of Inhibition Toward Acetylcholinesterase and Butyrylcholinesterase
- (2008) Sultan Darvesh et al. JOURNAL OF MEDICINAL CHEMISTRY
- Aging of Cholinesterases Phosphylated by Tabun Proceeds through O-Dealkylation
- (2008) Eugénie Carletti et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Crystal Structure of Thioflavin T Bound to the Peripheral Site ofTorpedo californicaAcetylcholinesterase Reveals How Thioflavin T Acts as a Sensitive Fluorescent Reporter of Ligand Binding to the Acylation Site
- (2008) Michal Harel et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- HOLLOW: Generating Accurate Representations of Channel and Interior Surfaces in Molecular Structures
- (2008) Bosco K Ho et al. BMC STRUCTURAL BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation