Evolution of Complex Target SELEX to Identify Aptamers against Mammalian Cell-Surface Antigens

Ligand-guided selection of aptamers against T-cell Receptor-cluster of differentiation 3 (TCR-CD3) expressed on Jurkat.E6 cells

(2016) Hasan E. Zumrut et al.   ANALYTICAL BIOCHEMISTRY

Intercellular Connections Related to Cell-Cell Crosstalk Specifically Recognized by an Aptamer

(2016) Nan Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Measure for Measure: Biomarker standards and transparency

(2016) Garret A. FitzGerald   Science Translational Medicine

Fit for the Eye: Aptamers in Ocular Disorders

(2016) Daniel W. Drolet et al.   Nucleic Acid Therapeutics

Ligand-Guided Selection of Target-Specific Aptamers: A Screening Technology for Identifying Specific Aptamers Against Cell-Surface Proteins

(2016) Hasan E. Zumrut et al.   Nucleic Acid Therapeutics

Aptamers: Promising Tools for the Detection of Circulating Tumor Cells

(2016) Eman M. Hassan et al.   Nucleic Acid Therapeutics

Generating Cell Targeting Aptamers for Nanotheranostics Using Cell-SELEX

(2016) Yifan Lyu et al.   Theranostics

Aptamer-miRNA-212 Conjugate Sensitizes NSCLC Cells to TRAIL

(2016) Margherita Iaboni et al.   Molecular Therapy-Nucleic Acids

Targeting Insulin Receptor with a Novel Internalizing Aptamer

(2016) Margherita Iaboni et al.   Molecular Therapy-Nucleic Acids

From selection hits to clinical leads: progress in aptamer discovery

(2016) Keith E Maier et al.   Molecular Therapy-Methods & Clinical Development

Evolution of DNA Aptamers through in Vitro Metastatic-Cell-Based Systematic Evolution of Ligands by Exponential Enrichment for Metastatic Cancer Recognition and Imaging

(2015) Xilan Li et al.   ANALYTICAL CHEMISTRY

A Versatile Approach Towards Nucleobase-Modified Aptamers

(2015) Fabian Tolle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modulation of the Coagulation Cascade Using AptamersSignificance

(2015) Rebecca S. Woodruff et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Characterization and target identification of a DNA aptamer that labels pluripotent stem cells

(2015) Zhonggang Hou et al.   CELL RESEARCH

Gene Knockdown by EpCAM Aptamer-siRNA Chimeras Suppresses Epithelial Breast Cancers and Their Tumor-Initiating Cells

(2015) A. Gilboa-Geffen et al.   MOLECULAR CANCER THERAPEUTICS

The Assessment of the Readiness of Molecular Biomarker-Based Mobile Health Technologies for Healthcare Applications

(2015) Chu Qin et al.   Scientific Reports

Developing aptamer probes for acute myelogenous leukemia detection and surface protein biomarker discovery

(2014) Mingli Yang et al.   Journal of Hematology & Oncology

High Temperature SELMA: Evolution of DNA-Supported Oligomannose Clusters Which Are Tightly Recognized by HIV bnAb 2G12

(2014) J. Sebastian Temme et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeted Inhibition of Prostate Cancer Metastases with an RNA Aptamer to Prostate-specific Membrane Antigen

(2014) Justin P Dassie et al.   MOLECULAR THERAPY

Oligonucleotide Aptamers: New Tools for Targeted Cancer Therapy

(2014) Hongguang Sun et al.   Molecular Therapy-Nucleic Acids

Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents

(2014) John C Rohloff et al.   Molecular Therapy-Nucleic Acids

Aptamer Identification of Brain Tumor-Initiating Cells

(2013) Y. Kim et al.   CANCER RESEARCH

In vitro selection with artificial expanded genetic information systems

(2013) K. Sefah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

X-Aptamers: A Bead-Based Selection Method for Random Incorporation of Druglike Moieties onto Next-Generation Aptamers for Enhanced Binding

(2012) Weiguo He et al.   BIOCHEMISTRY

Therapeutic RNA aptamers in clinical trials

(2012) Padma Sundaram et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Cell-based selection provides novel molecular probes for cancer stem cells

(2012) Kwame Sefah et al.   INTERNATIONAL JOURNAL OF CANCER

Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers

(2012) Kristina W. Thiel et al.   NUCLEIC ACIDS RESEARCH

An RNA Alternative to Human Transferrin: A New Tool for Targeting Human Cells

(2012) Samantha E Wilner et al.   Molecular Therapy-Nucleic Acids

Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery

(2011) Larry Gold et al.   PLoS One

Fluorescence-activated cell sorting for aptamer SELEX with cell mixtures

(2010) Günter Mayer et al.   Nature Protocols

Aptamers as therapeutics

(2010) Anthony D. Keefe et al.   NATURE REVIEWS DRUG DISCOVERY

What are biomarkers?

(2010) Kyle Strimbu et al.   Current Opinion in HIV and AIDS

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors

(2009) Justin P Dassie et al.   NATURE BIOTECHNOLOGY

Differential SELEX in Human Glioma Cell Lines

(2009) Laura Cerchia et al.   PLoS One

Complex Target SELEX

(2008) Steven M. Shamah et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cell-Specific Aptamer Probes for Membrane Protein Elucidation in Cancer Cells

(2008) Dihua Shangguan et al.   JOURNAL OF PROTEOME RESEARCH

Cell-Specific Internalization Study of an Aptamer from Whole Cell Selection

(2007) Zeyu Xiao et al.   CHEMISTRY-A EUROPEAN JOURNAL