Determination of Structural Requirements of N-Substituted Tetrahydro-β-Carboline Imidazolium Salt Derivatives Using in Silico Approaches for Designing MEK-1 Inhibitors

Enhancing the Enrichment of Pharmacophore-Based Target Prediction for the Polypharmacological Profiles of Drugs

(2016) Xia Wang et al.   Journal of Chemical Information and Modeling

Synthesis and antitumor activity of novel N-substituted tetrahydro-β-carboline–imidazolium salt derivatives

(2016) Bei Zhou et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Biosensor based on inhibition of monoamine oxidases A and B for detection of β-carbolines

(2015) Maria-Cristina Radulescu et al.   TALANTA

MEK 1/2 inhibitors in the treatment of hepatocellular carcinoma

(2015) Antonio Facciorusso et al.   Expert Review of Gastroenterology & Hepatology

Intrinsic and acquired resistance to MEK1/2 inhibitors in cancer

(2014) Matthew J. Sale et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Harmicine, a Tetracyclic Tetrahydro-β-Carboline: From the First Synthetic Precedent to Isolation from Natural Sources to Target-Oriented Synthesis (Review)*

(2014) C. S. Lood et al.   Chemistry of Heterocyclic Compounds

A Phase II Study of the Efficacy and Safety of the Combination Therapy of the MEK Inhibitor Refametinib (BAY 86-9766) Plus Sorafenib for Asian Patients with Unresectable Hepatocellular Carcinoma

(2014) H. Y. Lim et al.   CLINICAL CANCER RESEARCH

Refametinib

(2014) A. Lammers et al.   DRUGS OF THE FUTURE

Natural and synthetic acridines/acridones as antitumor agents: their biological activities and methods of synthesis

(2014) Grzegorz Cholewiński et al.   Pharmacological Reports

Particle Carriers for Combating Multidrug-Resistant Cancer

(2013) Yan Yan et al.   ACS Nano

CoMFA QSAR models of camptothecin analogues based on the distinctive SAR features of combined ABC, CD and E ring substitutions

(2012) Bastikar Virupaksha et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Synthesis and cytotoxic activities of novel hybrid compounds of imidazole scaffold-based 2-substituted benzofurans

(2012) Wen-Jian Song et al.   RSC Advances

Docking-based CoMFA and CoMSIA analyses of tetrahydro-β-carboline derivatives as type-5 phosphodiesterase inhibitors

(2011) Elena Cichero et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Anti-Plasmodium activity of imidazolium and triazolium salts

(2010) Jason Z. Vlahakis et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery of tetrahydro-β-carbolines as inhibitors of the mitotic kinesin KSP

(2010) Fei Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Bivalent β-Carbolines as Potential Multitarget Anti-Alzheimer Agents

(2010) Yvonne Rook et al.   JOURNAL OF MEDICINAL CHEMISTRY

PharmMapper server: a web server for potential drug target identification using pharmacophore mapping approach

(2010) Xiaofeng Liu et al.   NUCLEIC ACIDS RESEARCH

In Silico and In Vitro: Identifying New Drugs

(2008) Ivani Pauli et al.   CURRENT DRUG TARGETS

Design and synthesis of trans 2-(furan-2-yl)vinyl heteroaromatic iodides with antitumour activity

(2007) Cosimo Gianluca Fortuna et al.   BIOORGANIC & MEDICINAL CHEMISTRY