Attenuation of ketamine-induced impairment in verbal learning and memory in healthy volunteers by the AMPA receptor potentiator PF-04958242

Brain Rhythms Connect Impaired Inhibition to Altered Cognition in Schizophrenia

(2015) Benjamin R. Pittman-Polletta et al.   BIOLOGICAL PSYCHIATRY

Cognitive impairment in schizophrenia: the great unmet need

(2015) Ralph Aquila et al.   CNS SPECTRUMS

The Discovery and Characterization of the α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Potentiator N-{(3S,4S)-4-[4-(5-Cyano-2-thienyl)phenoxy]tetrahydrofuran-3-yl}propane-2-sulfonamide (PF-04958242)

(2015) Christopher L. Shaffer et al.   JOURNAL OF MEDICINAL CHEMISTRY

Glutamate and dopamine in schizophrenia: An update for the 21st century

(2015) Oliver Howes et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Calibration and cross-validation of MCCB and CogState in schizophrenia

(2015) Jane Lees et al.   PSYCHOPHARMACOLOGY

Exome Sequence Data From Multigenerational Families Implicate AMPA Receptor Trafficking in Neurocognitive Impairment and Schizophrenia Risk

(2015) Mark Z. Kos et al.   SCHIZOPHRENIA BULLETIN

Rhythmic Working Memory Activation in the Human Hippocampus

(2015) Marcin Leszczyński et al.   Cell Reports

α-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid receptor activation protects against phencyclidine-induced caspase-3 activity by activating voltage-gated calcium channels

(2014) Jennifer M. Timpe et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Loss of Phenotype of Parvalbumin Interneurons in Rat Prefrontal Cortex Is Involved in Antidepressant- and Propsychotic-Like Behaviors Following Acute and Repeated Ketamine Administration

(2014) ZhiQiang Zhou et al.   MOLECULAR NEUROBIOLOGY

Enhancing ketamine translational pharmacology via receptor occupancy normalization

(2014) Christopher L. Shaffer et al.   NEUROPHARMACOLOGY

Discovery and Characterization of a Novel Dihydroisoxazole Class of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) Receptor Potentiators

(2013) Nandini C. Patel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Reviewing the ketamine model for schizophrenia

(2013) Joel Frohlich et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Ketamine alters oscillatory coupling in the hippocampus

(2013) Fábio V. Caixeta et al.   Scientific Reports

Nicotine Fails to Attenuate Ketamine-Induced Cognitive Deficits and Negative and Positive Symptoms in Humans: Implications for Schizophrenia

(2012) Deepak Cyril D'Souza et al.   BIOLOGICAL PSYCHIATRY

CPP alters theta/gamma oscillations in rat hippocampus: simulation and experiment

(2012) Mohamed A Sherif et al.   BMC NEUROSCIENCE

Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy

(2012) Mark J. Millan et al.   NATURE REVIEWS DRUG DISCOVERY

The NMDA receptor as a target for cognitive enhancement

(2012) Graham L. Collingridge et al.   NEUROPHARMACOLOGY

Ketamine Disrupts Theta Modulation of Gamma in a Computer Model of Hippocampus

(2011) S. A. Neymotin et al.   JOURNAL OF NEUROSCIENCE

Schizophrenia and tobacco smoking comorbidity: nAChR agonists in the treatment of schizophrenia-associated cognitive deficits

(2011) Manoranjan S. D’Souza et al.   NEUROPHARMACOLOGY

Glycine Transporter Inhibitor Attenuates the Psychotomimetic Effects of Ketamine in Healthy Males: Preliminary Evidence

(2011) Deepak Cyril D'Souza et al.   NEUROPSYCHOPHARMACOLOGY

From Revolution to Evolution: The Glutamate Hypothesis of Schizophrenia and its Implication for Treatment

(2011) Bita Moghaddam et al.   NEUROPSYCHOPHARMACOLOGY

Three Year Follow-Up Study of an Integrated Supported Employment for Individuals with Severe Mental Illness

(2010) Hector W.H. Tsang et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

Prevention of ketamine-induced working memory impairments by AMPA potentiators in a nonhuman primate model of cognitive dysfunction

(2010) Brooke M. Roberts et al.   BEHAVIOURAL BRAIN RESEARCH

Working Memory: The Importance of Theta and Gamma Oscillations

(2010) John Lisman   CURRENT BIOLOGY

Group 5 metabotropic glutamate receptors: Role in modulating cortical activity and relevance to cognition

(2010) Houman Homayoun et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Delta oscillation and short-term plasticity in the rat medial prefrontal cortex: modelling NMDA hypofunction of schizophrenia

(2010) Tamás Kiss et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Positive Allosteric Modulators of the α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor

(2010) Simon J. A. Grove et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of 4-(5-Methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a Novel α7 Nicotinic Acetylcholine Receptor Agonist for the Treatment of Cognitive Disorders in Schizophrenia: Synthesis, SAR Development, and in Vivo Efficacy in Cognition Models

(2010) Christopher J. O’Donnell et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cross-frequency coupling supports multi-item working memory in the human hippocampus

(2010) N. Axmacher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Validity of the CogState Brief Battery: Relationship to Standardized Tests and Sensitivity to Cognitive Impairment in Mild Traumatic Brain Injury, Schizophrenia, and AIDS Dementia Complex

(2009) P. Maruff et al.   ARCHIVES OF CLINICAL NEUROPSYCHOLOGY

Treating the Cognitive Deficits of Schizophrenia with Alpha4Beta2 Neuronal Nicotinic Receptor Agonists

(2009) Richard Radek et al.   CURRENT PHARMACEUTICAL DESIGN

Activity-dependent synaptic plasticity of NMDA receptors

(2009) Nelson Rebola et al.   JOURNAL OF PHYSIOLOGY-LONDON

AC-260584, an orally bioavailable M1 muscarinic receptor allosteric agonist, improves cognitive performance in an animal model

(2009) Stefania Risso Bradley et al.   NEUROPHARMACOLOGY