Autism spectrum disorders and autistic traits share genetics and biology

An integrated molecular landscape implicates the regulation of dendritic spine formation through insulin-related signalling in obsessive–compulsive disorder

(2016) Ilse van de Vondervoort et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

The autism-associated MET receptor tyrosine kinase engages early neuronal growth mechanism and controls glutamatergic circuits development in the forebrain

(2016) Y Peng et al.   MOLECULAR PSYCHIATRY

Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia

(2016) S P Hagenaars et al.   MOLECULAR PSYCHIATRY

Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population

(2016) Elise B Robinson et al.   NATURE GENETICS

Obsessive–compulsive symptoms in a large population-based twin-family sample are predicted by clinically based polygenic scores and by genome-wide SNPs

(2016) A den Braber et al.   Translational Psychiatry

Heritability of autism spectrum disorders: a meta-analysis of twin studies

(2015) Beata Tick et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Phenome-wide analysis of genome-wide polygenic scores

(2015) E Krapohl et al.   MOLECULAR PSYCHIATRY

Excess of rare, inherited truncating mutations in autism

(2015) Niklas Krumm et al.   NATURE GENETICS

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

PRSice: Polygenic Risk Score software

(2014) Jack Euesden et al.   BIOINFORMATICS

False discovery rate control is a recommended alternative to Bonferroni-type adjustments in health studies

(2014) Mark E. Glickman et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

MicroRNA-137 regulates a glucocorticoid receptor–dependent signalling network: implications for the etiology of schizophrenia

(2014) Astrid Vallès et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Most genetic risk for autism resides with common variation

(2014) Trent Gaugler et al.   NATURE GENETICS

Variability in the common genetic architecture of social-communication spectrum phenotypes during childhood and adolescence

(2014) Beate St Pourcain et al.   Molecular Autism

High Loading of Polygenic Risk for ADHD in Children With Comorbid Aggression

(2013) Marian L. Hamshere et al.   AMERICAN JOURNAL OF PSYCHIATRY

Genome-Wide Association Study of Autistic-Like Traits in a General Population Study of Young Adults

(2013) Rachel Maree Jones et al.   Frontiers in Human Neuroscience

Candidate Genetic Pathways for Attention-Deficit/Hyperactivity Disorder (ADHD) Show Association to Hyperactive/Impulsive Symptoms in Children With ADHD

(2013) Janita Bralten et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

(2013)   LANCET

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

(2013) S Hong Lee et al.   NATURE GENETICS

Characterization of SLITRK1 Variation in Obsessive-Compulsive Disorder

(2013) Uzoezi Ozomaro et al.   PLoS One

Associations between polymorphisms in sex steroid related genes and autistic-like traits

(2013) Anna Zettergren et al.   PSYCHONEUROENDOCRINOLOGY

Power and Predictive Accuracy of Polygenic Risk Scores

(2013) Frank Dudbridge   PLoS Genetics

AKAPs integrate genetic findings for autism spectrum disorders

(2013) G Poelmans et al.   Translational Psychiatry

Autism Spectrum Disorders and Autisticlike Traits

(2012) Sebastian Lundström   ARCHIVES OF GENERAL PSYCHIATRY

Autism spectrum disorders and autistic traits: A decade of new twin studies

(2011) Angelica Ronald et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Association of the Alzheimer's GeneSORL1With Hippocampal Volume in Young, Healthy Adults

(2011) Janita Bralten et al.   AMERICAN JOURNAL OF PSYCHIATRY

Integrated Genome-Wide Association Study Findings: Identification of a Neurodevelopmental Network for Attention Deficit Hyperactivity Disorder

(2011) Geert Poelmans et al.   AMERICAN JOURNAL OF PSYCHIATRY

Evidence That Autistic Traits Show the Same Etiology in the General Population and at the Quantitative Extremes (5%, 2.5%, and 1%)

(2011) Elise B. Robinson   ARCHIVES OF GENERAL PSYCHIATRY

Gene set analysis of genome-wide association studies: Methodological issues and perspectives

(2011) Lily Wang et al.   GENOMICS

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Understanding mechanisms underlying human gene expression variation with RNA sequencing

(2010) Joseph K. Pickrell et al.   NATURE

Genotype imputation for genome-wide association studies

(2010) Jonathan Marchini et al.   NATURE REVIEWS GENETICS

Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS

(2010) Dan L. Nicolae et al.   PLoS Genetics

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

High-Resolution Mapping of Expression-QTLs Yields Insight into Human Gene Regulation

(2008) Jean-Baptiste Veyrieras et al.   PLoS Genetics