Article
Nutrition & Dietetics
Hwan-Hee Jang, In-Guk Hwang, Young-Min Lee
Summary: This study evaluated the effects of anthocyanin intake on blood lipid levels by analyzing relevant randomized controlled trials. The results showed that anthocyanin supplementation significantly reduced triglyceride and low-density lipoprotein-cholesterol levels, and increased high-density lipoprotein-cholesterol levels. However, larger, well-designed clinical trials are needed to further investigate the effects of anthocyanin intake on blood lipid levels and the safety of anthocyanin supplementation for treating dyslipidemia.
FRONTIERS IN NUTRITION
(2023)
Review
Biochemistry & Molecular Biology
Amirhossein Sahebkar, Zahra Heidari, Zahra Kiani, Masoumeh Atefi, Azadeh Zareie, Mehrnaz Shojaei, Gholamreza Askari, Prashant Kesharwani, Mohammad Bagherniya
Summary: This meta-analysis evaluated the effects of the DASH diet on lipid profiles based on clinical controlled trials. The results showed that following the DASH diet significantly reduced serum triglycerides and low-density lipoprotein cholesterol levels, but had no significant effect on serum total cholesterol and high-density lipoprotein cholesterol levels. Therefore, the DASH diet can be considered as a strategy for the prevention and complementary management of dyslipidemia.
CURRENT MEDICINAL CHEMISTRY
(2023)
Review
Nutrition & Dietetics
Saeed Mastour Alshahrani, Reham M. Mashat, Diaa Almutairi, Alaa Mathkour, Sahar Saad Alqahtani, Amirah Alasmari, Abdullah Hassan Alzahrani, Reem Ayed, Mohammed Yahya Asiri, Alsanussi Elsherif, Abdullah Alsabaani
Summary: Cardiovascular diseases (CVD) are a leading cause of global death. Walnut intake has been found to improve blood lipid profiles and reduce the risk of CVD. A meta-analysis of 13 trials found that walnut intake was associated with significant reductions in total cholesterol, low-density lipoprotein cholesterol, and triglycerides. Subgroup analysis revealed that overweight/obese individuals and those with comorbidities experienced greater lipid improvements. Longer trial durations led to further improvements. However, extraneous confounding factors and heterogeneity levels may affect the reliability of the results.
Review
Pharmacology & Pharmacy
Betina M. R. Carvalho, Laranda C. Nascimento, Jessica C. Nascimento, Vitoria S. dos S. Goncalves, Patricia K. Ziegelmann, Debora S. Tavares, Adriana G. Guimaraes
Summary: This study aims to obtain scientific evidence on the use of Citrus to control dyslipidemia. The study found that Citrus products have positive effects on dyslipidemia, reducing total cholesterol, LDL, and triglycerides levels, while increasing HDL.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Endocrinology & Metabolism
Chunyan Zhao, Yueqi Wang, Liu Xiao, Lin Li
Summary: The results of this meta-analysis suggest that levothyroxine treatment may reduce total cholesterol, triglycerides, low-density lipoprotein cholesterol, and apolipoprotein B levels in older patients with subclinical hypothyroidism (SCH). However, it does not significantly affect bone mineral density, fatigue, hypothyroidism symptoms, quality of life, body mass index, cognitive function, depression, blood pressure, or increase the incidence of adverse events in older SCH patients.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Endocrinology & Metabolism
Parham Mardi, Fatemeh Abdi, Amir Ehsani, Ehsan Seif, Shirin Djalalinia, Javad Heshmati, Ehsan Shahrestanaki, Armita Mahdavi Gorabi, Mostafa Qorbani
Summary: This study examined the association between novel atherogenic lipid indices (including non-HDL-C, atherogenic index, and the difference between non-HDL-C and LDL-C) and metabolic syndrome (MetS) or its components. The results showed a strong correlation between these indices and increased odds of MetS and its components.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Obstetrics & Gynecology
Zhen Wang, Lanlan Fang, Ze Wu, Yuxi Li, Qiongqiong Jia, Jung-Chien Cheng, Ying-Pu Sun
Summary: The meta-analysis findings suggest that patients with premature ovarian insufficiency (POI) have significantly higher levels of serum total cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglyceride, but no significant difference in high-density lipoprotein cholesterol (HDL-C) levels compared to controls. These results indicate that elevations in unfavorable lipids may contribute to the increased risk of cardiovascular diseases observed in patients with POI.
REPRODUCTIVE BIOMEDICINE ONLINE
(2022)
Article
Clinical Neurology
Jinling Du, Yijia Chen, Nan Zhou, Yingqian Song, Weiwei Wang, Xin Hong
Summary: There is a U-shaped correlation between sleep duration and abnormal serum lipid profiles, and both shorter and longer sleep durations are associated with abnormal serum lipids in both men and women.
Review
Obstetrics & Gynecology
Yongchi Zhan, Tingting Xu, Tiantian Chen, Xiaodong Wang
Summary: This systematic review and meta-analysis aimed to evaluate the association between intrahepatic cholestasis of pregnancy (ICP) and maternal lipid metabolism. The results showed a significant association between ICP and maternal dyslipidemia, indicating that ICP pregnancies have dysregulated lipid metabolism compared to normal pregnancies.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2022)
Article
Food Science & Technology
Shuidong Feng, Mengyue Cao, Peng Tang, Shuxiang Deng, Limou Chen, Yan Tang, Lemei Zhu, Xiang Chen, Zhijun Huang, Minxue Shen, Fei Yang
Summary: Increasing experimental evidence suggests a link between exposure to microcystins (MCs) and lipid metabolism disorder. This population-based study in China examined the association between MCs exposure and dyslipidemia risk. The results showed that higher levels of MCs exposure were significantly associated with an increased risk of dyslipidemia, elevated triglyceride levels, and reduced high-density lipoprotein cholesterol levels. The study also found an additive antagonistic effect between MCs and a metal called Zn on dyslipidemia.
Review
Nutrition & Dietetics
Shima Abdollahi, Asma Kazemi, Russell J. de Souza, Cain C. T. Clark, Sepideh Soltani
Summary: Based on the analysis of 21 randomized controlled trials, higher meal frequency may improve total cholesterol and low-density lipoprotein cholesterol levels, but has insignificant effects on glycemic control and leptin. However, the current evidence quality is low, calling for more high-quality studies to confirm the conclusions.
CLINICAL NUTRITION
(2021)
Review
Pharmacology & Pharmacy
Kyung U. Hong, Kennedy M. Walls, David W. Hein
Summary: Arylamine N-acetyltransferase 2 (NAT2) is an important metabolic enzyme involved in the metabolism of aromatic amines and hydrazines. Genetic variants in the coding region of NAT2 can affect enzyme activity and protein stability, leading to different acetylator phenotypes. Recent genome wide association studies have discovered non-coding or intergenic variants of NAT2 that are associated with elevated plasma lipid and cholesterol levels, suggesting a new role of NAT2 in lipid and cholesterol homeostasis.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Xiao Huang, Yan Yang, Yingling Jiang, Zhiguang Zhou, Jingjing Zhang
Summary: This study aimed to determine the relationship between lipid profiles and vitamin D deficiency in overweight and obese adults. The results showed that individuals with vitamin D deficiency had higher levels of triglycerides, total cholesterol, and low-density lipoprotein cholesterol, and lower levels of high-density lipoprotein cholesterol.
Review
Plant Sciences
Mohammad Sadegh Adel Mehraban, Ozra Tabatabaei-Malazy, Roja Rahimi, Marzieh Daniali, Patricia Khashayar, Bagher Larijani
Summary: This systematic review critically assessed meta-analyses of controlled trials evaluating herbal medicines for dyslipidemia. Various herbal remedies such as vegetable oils, phytosterols, tea, soy protein, nuts, and curcumin were found to potentially improve lipid profiles. However, more well-conducted controlled trials are needed to determine the effective doses of these herbal medicines.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Review
Cardiac & Cardiovascular Systems
Xiaoxian Gong, Luowei Chen, Bo Song, Xiang Han, Weihai Xu, Bo Wu, Feng Sheng, Min Lou
Summary: The study found that an increase in total cholesterol and triglycerides is associated with an increased risk of ischemic stroke and a reduced risk of hemorrhagic stroke, while an increase in high-density lipoprotein cholesterol is associated with a reduced risk of ischemic stroke. It is recommended to control total cholesterol and low-density lipoprotein cholesterol levels within certain ranges.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
