Article
Food Science & Technology
Rosa M. Valls, Anna Pedret, Lorena Calderon-Perez, Elisabet Llaurado, Laura Pla-Paga, Judit Companys, Ana Moragas, Francisco Martin-Lujan, Yolanda Ortega, Montse Giralt, Laura Rubio, Nuria Canela, Francesc Puiggros, Antoni Caimari, Josep M. Del Bas, Lluis Arola, Rosa Sola
Summary: After 12 weeks of sustained consumption, orange juice enriched with hesperidin significantly increased ischaemic reactive hyperemia, improved endothelial function, reduced systemic inflammatory levels, and affected transcriptomic levels, suggesting a potential mechanism for the observed increase in IRH.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Nutrition & Dietetics
Lea Tischmann, Tanja C. Adam, Ronald P. Mensink, Peter J. Joris
Summary: This study investigated the longer-term effects of soy nut consumption on vascular function and cardiometabolic risk markers in healthy older adults. The results showed that long-term soy nut intake improved endothelial function, reduced LDL-cholesterol concentrations, and lowered mean arterial pressure.
CLINICAL NUTRITION
(2022)
Article
Peripheral Vascular Disease
Sheldon W. Tobe, Lisa Dubrofsky, Daniel Nasser, Raveenie Rajasingham, Martin G. Myers
Summary: The Zero to Five study demonstrated that a 0-minute wait before an AOBP measurement was closer to the awake ABPM result than a 5-minute wait.
Article
Nutrition & Dietetics
Maarten C. Bosland, Erika Enk, Joanne Schmoll, Michael J. Schlicht, Carla Randolph, Ryan J. Deaton, Hui Xie, Anne Zeleniuch-Jacquotte, Ikuko Kato
Summary: This study found that a 2-year soy protein supplementation did not have significant effects on body weight, blood pressure, blood lipids, iron status, and other clinical chemistry parameters in middle-aged to older men. Additional exploratory analysis suggested that equol production status might modulate the effects of soy on body weight and possibly blood pressure.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Critical Care Medicine
William Checkley, Kendra N. Williams, Josiah L. Kephart, Magdalena Fandino-Del-Rio, N. Kyle Steenland, Gustavo F. Gonzales, Luke P. Naeher, Steven A. Harvey, Lawrence H. Moulton, Victor G. Davila-Roman, Dina Goodman, Carla Tarazona-Meza, Catherine H. Miele, Suzanne Simkovich, Marilu Chiang, Ryan T. Chartier, Kirsten Koehler
Summary: A study was conducted in rural Puno, Peru involving 180 women aged 25-64 to determine the impact of an intervention using Liquefied Petroleum Gas (LPG) on cardiopulmonary health outcomes. Despite high adherence to LPG stove usage in the intervention group, there were no significant differences in blood pressure, lung function, or respiratory symptoms compared to the control group over a 1-year period.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2021)
Article
Food Science & Technology
Marina Boix-Castejon, Maria Herranz-Lopez, Marilo Olivares-Vicente, Paula Campoy, Nuria Caturla, Jonathan Jones, Juan M. Zazo, Enrique Roche, Vicente Micol
Summary: The study evaluated the antihypertensive effects of a botanical nutraceutical product on prehypertensive and early stage 1 hypertensive individuals, finding significant reductions in blood pressure, body fat content, and improvements in dipper status. These results suggest that the nutraceutical can serve as a main regulator of blood pressure towards healthier values in this population.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Multidisciplinary Sciences
Cristian Del Bo', Massimiliano Tucci, Daniela Martini, Mirko Marino, Simona Bertoli, Alberto Battezzati, Marisa Porrini, Patrizia Riso
Summary: Aging individuals are at higher risk of cardiovascular disease, but berries, particularly blueberries, may have beneficial effects on vascular function. This study aims to investigate the effects of blueberry consumption on markers related to oxidative stress, inflammation, and vascular function in older subjects. The study will also provide data on the absorption and metabolism of blueberry bioactives.
Article
Medicine, General & Internal
Tina Tomic Mahecic, Branko Malojcic, Dinko Tonkovic, Mirabel Mazar, Robert Baronica, Snjezana Juren Measki, Andrea Crkvenac Gregorek, Jens Meier, Martin W. W. Duenser
Summary: This single-center trial examined the impact of near-infrared spectroscopy (NIRS)-guided blood pressure management on neurocognitive function and perioperative complications in patients undergoing carotid endarterectomy (CEA). The results showed that the intervention group, guided by NIRS, had lower systolic blood pressure and norepinephrine doses during carotid cross-clamping, as well as a lower rate of perioperative complications.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Clinical Neurology
Benjamin Maier, Benjamin Gory, Bertrand Lapergue, Igor Sibon, Simon Escalard, Maeva Kyheng, Julien Labreuche, Adam de Havenon, Nils Petersen, Mohammad Anadani, Etienne Gayat, Perrine Boursin, Malek Ben Maacha, Jean-Philippe Desilles, Raphael Blanc, Michel Piotin, Jean-Michel Halimi, Mikael Mazighi
Summary: This study conducted a post hoc analysis to evaluate the impact of blood pressure variability (BPV) on functional outcomes and intracranial hemorrhage (ICH) in acute ischemic stroke patients. The results showed that BPV was significantly higher in the intensive systolic blood pressure target group but was not associated with functional outcomes or ICH.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Nutrition & Dietetics
Yee Xing You, Suzana Shahar, Nor Fadilah Rajab, Hasnah Haron, Hanis Mastura Yahya, Mazlyfarina Mohamad, Normah Che Din, Mohamad Yusof Maskat
Summary: Cosmos caudatus supplementation for 12 weeks showed significant improvements in cognitive function, mood status, and oxidative stress among older adults with mild cognitive impairment. Further studies with larger sample sizes and longer intervention periods incorporating metabolomic approaches are warranted to explore the underlying mechanisms.
Article
Nutrition & Dietetics
Jialu Yang, Jingyi Huang, Zhihao Huang, Yingxi Xu, Wenkang Li, Shanshan Zhu, Yawen Zhao, Bingqi Ye, Ludi Liu, Jiangyuan Zhu, Min Xia, Yan Liu
Summary: In this study, the effects of L. paracasei supplementation on cardiometabolic health in individuals with metabolic syndrome were investigated. The results showed that L. paracasei supplementation decreased remnant cholesterol levels, improved endothelial function, and alleviated the severity of metabolic syndrome. This study provides a feasible and safe strategy for the prevention of cardiometabolic diseases in individuals with dyslipidemia and endothelial dysfunction.
CLINICAL NUTRITION
(2023)
Article
Nutrition & Dietetics
David J. A. Jenkins, Peter J. H. Jones, Mohammad M. H. Abdullah, Benoit Lamarche, Dorothea Faulkner, Darshna Patel, Sandhya Sahye-Pudaruth, Melanie Paquette, Balachandran Bashyam, Sathish C. Pichika, Meaghan E. Kavanagh, Pooja Patel, Fred Liang, Ramon Brown, Tiffany Zhao, Mila Phan, Gajuna Mathiyalagan, Shilpa Tandon, Vladmir Vuksan, Elena Jovanovski, John L. Sievenpiper, Cyril W. C. Kendall, Lawrence A. Leiter, Robert G. Josse
Summary: Both low-carbohydrate vegan and vegetarian diets can contribute to weight loss, improved glycemic control, and blood pressure. However, the plant-based diet has greater potential in reducing greenhouse gas emissions.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Dylan L. Steen, Robert N. Helsley, Deepak L. Bhatt, Eileen C. King, Suzanne S. Summer, Matthew Fenchel, Brian E. Saelens, Mark H. Eckman, Sarah C. Couch
Summary: This study demonstrates the effectiveness of data-guided, supermarket-based dietary interventions and modern online shopping tools in improving dietary quality in a free-living, community-based population. It also highlights the opportunity for academic researchers to collaborate with retailers in designing and rigorously testing comprehensive healthcare interventions.
Article
Peripheral Vascular Disease
Liqiang Zheng, Sitong Liu, Yundi Jiao, Yani Wu, Yali Wang, Zhecong Yu, Jiahui Xu, Yingxian Sun, Zhaoqing Sun
Summary: This study found that financial incentives were effective in the short-term for controlling blood pressure in patients with poorly controlled hypertension, but did not show a sustained effect beyond 3 months of intervention. Future research is needed to identify the appropriate amount and structure of financial incentives for blood pressure control.
Review
Nutrition & Dietetics
Berner-Andree Sandoval-Ramirez, Ursula Catalan, Elisabet Llaurado, Rosa-Maria Valls, Patricia Salamanca, Laura Rubio, Silvia Yuste, Rosa Sola
Summary: Anthocyanins have significant positive effects on reducing the risks of hypertension and type 2 diabetes, while improving plasma lipids, glucose metabolism, and endothelial function. However, there is no association between anthocyanins and the risks of breast or gastric cancer. Anthocyanin intake provides new pathways for managing glucose metabolism, plasma lipid profiles, and improving endothelial function in humans.
Review
Food Science & Technology
Caroline R. Hill, Armaghan Shafaei, Lois Balmer, Joshua R. Lewis, Jonathan M. Hodgson, A. Harvey Millar, Lauren C. Blekkenhorst
Summary: Sulfur is an essential element for plant and human health, and its incorporation into the food chain relies heavily on plant uptake. The dietary requirements for sulfur are based on the synthesis of proteins, enzymes, co-enzymes, vitamins, and hormones. While sulfur-containing amino acids are abundant in animal sources, the variety and quantity of sulfur-containing compounds in plants also have wide-ranging effects on human health. The role of sulfur in redox biochemistry protects against oxidative stress and inflammation, which is consistent with cardiometabolic dysfunction and many chronic metabolic diseases.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Cardiac & Cardiovascular Systems
Reindolf Anokye, Ben Jackson, James Dimmock, Joanne M. Dickson, Lauren C. Blekkenhorst, Jonathan M. Hodgson, Joshua R. Lewis, Mandy Stanley
Summary: This article aims to investigate the psychological distress and changes in health-related quality of life (HRQoL) following cardiovascular risk assessment and communication of results to asymptomatic adults. Through a review of relevant studies, the findings on these aspects are found to be mixed.
EUROPEAN JOURNAL OF CARDIOVASCULAR NURSING
(2023)
Article
Cardiac & Cardiovascular Systems
Natalie C. Ward, Gerald F. Watts, Warrick Bishop, David Colquhoun, Christian Hamilton-Craig, David L. Hare, Nadarajah Kangaharan, Karam M. Kostner, Leonard Kritharides, Richard O'Brien, Trevor A. Mori, Paul J. Nestel, Stephen J. Nicholls, Natalie Raffoul, Harvey D. White, David R. Sullivan
Summary: This position statement provides guidance to cardiologists and related specialists on the management of adult patients with elevated lipoprotein(a) [Lp(a)]. Elevated Lp(a) is an independent and causal risk factor for atherosclerotic cardiovascular disease (ASCVD) and calcific aortic valve disease (CAVD). Selective screening strategies of high-risk patients are recommended, but universal screening of the population is currently not advised. Testing for elevated Lp(a) is recommended in all patients with premature ASCVD and those considered to be at intermediate-to-high risk of ASCVD. Apheresis should be considered in patients with progressive ASCVD. New ribonucleic acid (RNA)-based therapies which directly lower Lp(a) are undergoing clinical trials.
HEART LUNG AND CIRCULATION
(2023)
Article
Substance Abuse
Reece De Zylva, Elissa Mortimer, Emma Miller, George Tsourtos, Sharon Lawn, Carlene Wilson, Jonathan Karnon, Richard Woodman, Paul Ward
Summary: The study aims to test the effectiveness of online mindfulness-based interventions and peer support in promoting smoking cessation and resilience among low socioeconomic status smokers. It is a 12-month randomized controlled trial with four intervention groups and includes various outcome measures such as smoking abstinence, resilience, social support, quality of life, self-efficacy, motivation to quit, nicotine dependence, equanimity, stress, and goal attainment. This study is crucial for addressing the health issues of low socioeconomic status smokers.
ADDICTION SCIENCE & CLINICAL PRACTICE
(2023)
Article
Geriatrics & Gerontology
Abadi K. Gebre, Marc Sim, Jack Dalla Via, Alexander J. Rodriguez, Kun Zhu, John T. Schousboe, Jonathan M. Hodgson, Catherine P. Bondonno, Richard L. Prince, Joshua R. Lewis
Summary: In older women, cardiovascular disease, especially cerebrovascular disease, is associated with an increased risk of long-term falls. These findings emphasize the need to recognize increased falls risk in patients with cardiovascular disease.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2023)
Article
Nutrition & Dietetics
Daisy H. Coyle, Laura Sanavio, Eden Barrett, Liping Huang, Kristy K. Law, Pabasha Nanayakkara, Jonathan M. Hodgson, Merita O'Connell, Belinda Meggitt, Carrie Tsai, Simone Pettigrew, Jason H. Y. Wu
Summary: The study assessed the food environment at a university in Sydney and found that improvements are needed in terms of availability, placement, and promotion of healthy foods. Sugary drinks and unhealthy products were prevalent in the food outlets, and there was a lack of healthy options at checkout areas.
Article
Microbiology
Adilah F. Ahmad, Jose A. Caparros-Martin, Silvia Lee, Fergal O'Gara, Bu B. Yeap, Daniel J. Green, Mohammed Ballal, Natalie C. Ward, Girish Dwivedi
Summary: This observational cohort study found that there were no significant differences in gut bacterial diversity between obese patients before and after bariatric surgery compared to a healthy control group. However, there were differences in the abundance of certain bacterial groups between the two cohorts. Additionally, the study observed changes in the levels of specific short chain fatty acids and soluble CD14 and CD163 in obese patients before and after surgery compared to healthy controls.
Article
Nutrition & Dietetics
Anjana Rajendra, Nicola P. Bondonno, Kevin Murray, Liezhou Zhong, Stephanie R. Rainey-Smith, Samantha L. Gardener, Lauren C. Blekkenhorst, David Ames, Paul Maruff, Ralph N. Martins, Jonathan M. Hodgson, Catherine P. Bondonno
Summary: This study aimed to investigate the association between dietary nitrate intake from natural sources and cognitive function and decline. The results showed that in APOE ε4 carriers, intake of vegetable-derived and total nitrate was associated with better memory. However, there was no evidence of an association between dietary nitrate intake and rate of cognitive decline.
CLINICAL NUTRITION
(2023)
Review
Food Science & Technology
Caroline R. Hill, Alex Haoci Liu, Lyn Mccahon, Liezhou Zhong, Armaghan Shafaei, Lois Balmer, Joshua R. Lewis, Jonathan M. Hodgson, Lauren C. Blekkenhorst
Summary: Higher intakes of cruciferous and allium vegetables are associated with a lower risk of cardiometabolic-related outcomes. This scoping review explores the potential roles of S-methyl cysteine sulfoxide (SMCSO) found in these vegetables and its mechanisms of action. Animal studies suggest that SMCSO has anti-hyperglycemic, anti-hypercholesterolemic, antioxidant, anticancer, and antibacterial properties. More research, especially human studies, is needed to further understand the health benefits of SMCSO, particularly for cardiometabolic and inflammatory-based pathologies.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Clinical Neurology
Anna Tresserra-Rimbau, Alysha S. Thompson, Nicola Bondonno, Amy Jennings, Tilman Kuehn, Aedin Cassidy
Summary: This study found that following a healthful plant-based diet, especially including adequate amounts of vegetables, nuts, and tea, is associated with a lower risk of Parkinson's disease (PD) based on observations in the UK Biobank cohort.
MOVEMENT DISORDERS
(2023)
Article
Nutrition & Dietetics
Jocelyn M. Choo, Karen J. Murphy, Alexandra T. Wade, Yanan Wang, Ella L. Bracci, Courtney R. Davis, Kathryn A. Dyer, Richard J. Woodman, Jonathan M. Hodgson, Geraint B. Rogers
Summary: The impact of a Mediterranean diet supplemented with dairy foods on the gut microbiome in Australians at risk of cardiovascular disease was evaluated. The Mediterranean diet with 3-4 daily serves of dairy foods resulted in changes in the abundance of specific gut bacteria. Increases in Butyricicoccus relative abundance were inversely correlated with lower systolic blood pressure and positively correlated with changes in fasting glucose levels. These findings suggest that the MedDairy diet may have a positive effect on clinical outcomes in adults at risk of CVD.
Article
Gastroenterology & Hepatology
Shauna Madigan, Yasmina Tashkent, Sharad Trehan, Kate Muller, Alan Wigg, Richard Woodman, Jeyamani Ramachandran
Summary: Acute on chronic liver failure (ACLF) is a common clinical syndrome in patients with acute decompensation (AD) of cirrhosis, characterized by organ failures and high mortality. Liver transplantation (LT) is an important treatment to improve survival, but alcohol use disorder (AUD) is a barrier to LT assessment.
Review
Geriatrics & Gerontology
Richard J. Woodman, Arduino A. Mangoni
Summary: The increasing access to health data worldwide is driving a resurgence in machine learning research, including data-hungry deep learning algorithms. More computationally efficient algorithms now offer unique opportunities to enhance diagnosis, risk stratification, and individualised approaches to patient management. Clinical tools that utilise machine learning algorithms to determine the optimal choice of treatment are slowly gaining the necessary approval from governing bodies and being implemented into healthcare, with significant implications for virtually all medical disciplines during the next phase of digital medicine.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Article
Gastroenterology & Hepatology
Jean M. Winter, Kathryn J. Cornthwaite, Graeme P. Young, Carlene Wilson, Gang Chen, Richard Woodman, Michelle Coats, Robert Fraser, Charles Cock, Peter Bampton, Erin L. Symonds
Summary: The purpose of this study is to determine the safety, cost-effectiveness, and patient acceptance of extending colonoscopy surveillance intervals using the fecal immunochemical test (FIT) for individuals at elevated risk of colorectal cancer (CRC). Participants with a low FIT result will be randomized to either continue surveillance colonoscopy as scheduled or delay it by 1 or 2 years. The primary endpoint is the incidence of advanced neoplasia.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
(2023)
Article
Geriatrics & Gerontology
M. Sim, C. Smith, N. P. Bondonno, S. Radavelli-Bagatini, L. C. Blekkenhorst, J. Dalla Via, R. McCormick, K. Zhu, J. M. Hodgson, R. L. Prince, J. R. Lewis
Summary: This study suggests that a higher intake of Vitamin K1 is associated with better muscle function and lower risk of injurious falls in older women. However, Vitamin K2 intake does not show the same associations. Therefore, it is important to promote the consumption of Vitamin K1-rich foods, such as green leafy vegetables, for musculoskeletal health in older women.
JOURNAL OF NUTRITION HEALTH & AGING
(2023)
