Don’t let sleeping dogmas lie: new views of peptidoglycan synthesis and its regulation

Pentapeptide-rich peptidoglycan at theBacillus subtiliscell-division site

(2017) Danae Morales Angeles et al.   MOLECULAR MICROBIOLOGY

GTPase activity–coupled treadmilling of the bacterial tubulin FtsZ organizes septal cell wall synthesis

(2017) Xinxing Yang et al.   SCIENCE

Treadmilling by FtsZ filaments drives peptidoglycan synthesis and bacterial cell division

(2017) Alexandre W. Bisson-Filho et al.   SCIENCE

Contrasting mechanisms of growth in two model rod-shaped bacteria

(2017) Cyrille Billaudeau et al.   Nature Communications

The mecillinam resistome reveals a role for peptidoglycan endopeptidases in stimulating cell wall synthesis in Escherichia coli

(2017) Ghee Chuan Lai et al.   PLoS Genetics

RodA as the missing glycosyltransferase in Bacillus subtilis and antibiotic discovery for the peptidoglycan polymerase pathway

(2017) Kaveh Emami et al.   Nature Microbiology

Interplay between Penicillin-binding proteins and SEDS proteins promotes bacterial cell wall synthesis

(2017) Sophie Leclercq et al.   Scientific Reports

Biogenesis of the Gram-positive bacterial cell envelope

(2016) Sara D Siegel et al.   CURRENT OPINION IN MICROBIOLOGY

Bacillus subtilis extracytoplasmic function (ECF) sigma factors and defense of the cell envelope

(2016) John D Helmann   CURRENT OPINION IN MICROBIOLOGY

Regulation of bacterial cell wall growth

(2016) Alexander J. F. Egan et al.   FEBS Journal

Depletion of Undecaprenyl Pyrophosphate Phosphatases Disrupts Cell Envelope Biogenesis in Bacillus subtilis

(2016) Heng Zhao et al.   JOURNAL OF BACTERIOLOGY

Chemometric Analysis of Bacterial Peptidoglycan Reveals Atypical Modifications That Empower the Cell Wall against Predatory Enzymes and Fly Innate Immunity

(2016) Akbar Espaillat et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

SEDS proteins are a widespread family of bacterial cell wall polymerases

(2016) Alexander J. Meeske et al.   NATURE

Role of the Gram-Negative Envelope Stress Response in the Presence of Antimicrobial Agents

(2016) Randi L. Guest et al.   TRENDS IN MICROBIOLOGY

Single-molecule imaging reveals modulation of cell wall synthesis dynamics in live bacterial cells

(2016) Timothy K. Lee et al.   Nature Communications

Factors essential for L,D-transpeptidase-mediated peptidoglycan cross-linking and β-lactam resistance in Escherichia coli

(2016) Jean-Emmanuel Hugonnet et al.   eLife

Bacterial cell wall biogenesis is mediated by SEDS and PBP polymerase families functioning semi-autonomously

(2016) Hongbaek Cho et al.   Nature Microbiology

The O-Antigen Flippase Wzk Can Substitute for MurJ in Peptidoglycan Synthesis in Helicobacter pylori and Escherichia coli

(2016) Wael Elhenawy et al.   PLoS One

FtsZ does not initiate membrane constriction at the onset of division

(2016) Daniel O. Daley et al.   Scientific Reports

A D, D-carboxypeptidase is required forVibrio choleraehalotolerance

(2015) Andrea Möll et al.   ENVIRONMENTAL MICROBIOLOGY

Identification of MltG as a potential terminase for peptidoglycan polymerization in bacteria

(2015) Rachel Yunck et al.   MOLECULAR MICROBIOLOGY

Bacterial morphogenesis and the enigmatic MreB helix

(2015) Jeff Errington   NATURE REVIEWS MICROBIOLOGY

MurJ and a novel lipid II flippase are required for cell wall biogenesis inBacillus subtilis

(2015) Alexander J. Meeske et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RodZ links MreB to cell wall synthesis to mediate MreB rotation and robust morphogenesis

(2015) Randy M. Morgenstein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LipidII: Just Another Brick in the Wall?

(2015) Dirk-Jan Scheffers et al.   PLoS Pathogens

Chemical biology of peptidoglycan acetylation and deacetylation

(2014) Patrick J. Moynihan et al.   BIOORGANIC CHEMISTRY

Beta-Lactam Antibiotics Induce a Lethal Malfunctioning of the Bacterial Cell Wall Synthesis Machinery

(2014) Hongbaek Cho et al.   CELL

Bile-induced peptidoglycan remodelling inSalmonella enterica

(2014) Sara B. Hernández et al.   ENVIRONMENTAL MICROBIOLOGY

The Cpx Envelope Stress Response Modifies Peptidoglycan Cross-Linking via the l,d-Transpeptidase LdtD and the Novel Protein YgaU

(2014) Margarita Bernal-Cabas et al.   JOURNAL OF BACTERIOLOGY

A dynamically assembled cell wall synthesis machinery buffers cell growth

(2014) T. K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rod-like bacterial shape is maintained by feedback between cell curvature and cytoskeletal localization

(2014) T. S. Ursell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MurJ is the flippase of lipid-linked precursors for peptidoglycan biogenesis

(2014) L.-T. Sham et al.   SCIENCE

The actin homologue MreB organizes the bacterial cell membrane

(2014) Henrik Strahl et al.   Nature Communications

A Novel Peptidoglycan Binding Protein Crucial for PBP1A-Mediated Cell Wall Biogenesis in Vibrio cholerae

(2014) Tobias Dörr et al.   PLoS Genetics

Moenomycin Resistance Mutations in Staphylococcus aureus Reduce Peptidoglycan Chain Length and Cause Aberrant Cell Division

(2013) Yuriy Rebets et al.   ACS Chemical Biology

Wall Teichoic Acids of Gram-Positive Bacteria

(2013) Stephanie Brown et al.   Annual Review of Microbiology

MreB and MurG as scaffolds for the cytoplasmic steps of peptidoglycan biosynthesis

(2013) Sandy Favini-Stabile et al.   ENVIRONMENTAL MICROBIOLOGY

Tuning the Moenomycin Pharmacophore To Enable Discovery of Bacterial Cell Wall Synthesis Inhibitors

(2013) Christian M. Gampe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phenotypic analysis of Eschericia coli mutants lacking L,D-transpeptidases

(2013) A. N. Sanders et al.   MICROBIOLOGY-SGM

Substrate specificity of an elongation-specific peptidoglycan endopeptidase and its implications for cell wall architecture and growth ofVibrio cholerae

(2013) Tobias Dörr et al.   MOLECULAR MICROBIOLOGY

Peptidoglycan at its peaks: how chromatographic analyses can reveal bacterial cell wall structure and assembly

(2013) Samantha M. Desmarais et al.   MOLECULAR MICROBIOLOGY

FtsEX is required for CwlO peptidoglycan hydrolase activity during cell wall elongation inBacillus subtilis

(2013) Jeffrey Meisner et al.   MOLECULAR MICROBIOLOGY

Differentiated roles for MreB-actin isologues and autolytic enzymes inBacillus subtilismorphogenesis

(2013) Patricia Domínguez-Cuevas et al.   MOLECULAR MICROBIOLOGY

An early cytoplasmic step of peptidoglycan synthesis is associated to MreB inBacillus subtilis

(2013) Anne-Stéphanie Rueff et al.   MOLECULAR MICROBIOLOGY

The physiology of bacterial cell division

(2012) Alexander J. F. Egan et al.   Annals of the New York Academy of Sciences

Structural Perspective of Peptidoglycan Biosynthesis and Assembly

(2012) Andrew L. Lovering et al.   Annual Review of Biochemistry

Key genetic elements and regulation systems in methicillin-resistantStaphylococcus aureus

(2012) Haihong Hao et al.   Future Microbiology

Cooperativity of peptidoglycan synthases active in bacterial cell elongation

(2012) Manuel Banzhaf et al.   MOLECULAR MICROBIOLOGY

Three redundant murein endopeptidases catalyse an essential cleavage step in peptidoglycan synthesis ofEscherichia coliK12

(2012) Santosh Kumar Singh et al.   MOLECULAR MICROBIOLOGY

Bacterial growthdoesrequire peptidoglycan hydrolases

(2012) Waldemar Vollmer   MOLECULAR MICROBIOLOGY

Distinct pathways for modification of the bacterial cell wall by non-canonicalD-amino acids

(2011) Felipe Cava et al.   EMBO JOURNAL

Identification of FtsW as a transporter of lipid-linked cell wall precursors across the membrane

(2011) Tamimount Mohammadi et al.   EMBO JOURNAL

Location, synthesis and function of glycolipids and polyglycerolphosphate lipoteichoic acid in Gram-positive bacteria of the phylum Firmicutes

(2011) Nathalie T. Reichmann et al.   FEMS MICROBIOLOGY LETTERS

Monofunctional Transglycosylases Are Not Essential for Staphylococcus aureus Cell Wall Synthesis

(2011) P. Reed et al.   JOURNAL OF BACTERIOLOGY

The bacterial actin MreB rotates, and rotation depends on cell-wall assembly

(2011) S. van Teeffelen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Processive Movement of MreB-Associated Cell Wall Biosynthetic Complexes in Bacteria

(2011) J. Dominguez-Escobar et al.   SCIENCE

Coupled, Circumferential Motions of the Cell Wall Synthesis Machinery and MreB Filaments in B. subtilis

(2011) E. C. Garner et al.   SCIENCE

Lipoprotein Cofactors Located in the Outer Membrane Activate Bacterial Cell Wall Polymerases

(2010) Catherine Paradis-Bleau et al.   CELL

Regulation of Peptidoglycan Synthesis by Outer-Membrane Proteins

(2010) Athanasios Typas et al.   CELL

The Bacillus subtilis σM regulon and its contribution to cell envelope stress responses

(2010) Warawan Eiamphungporn et al.   MOLECULAR MICROBIOLOGY

Septal and lateral wall localization of PBP5, the major D,D-carboxypeptidase of Escherichia coli, requires substrate recognition and membrane attachment

(2010) Lakshmiprasad Potluri et al.   MOLECULAR MICROBIOLOGY

Positioning cell wall synthetic complexes by the bacterial morphogenetic proteins MreB and MreD

(2010) Courtney L. White et al.   MOLECULAR MICROBIOLOGY

The putative Bacillus subtilis l,d-transpeptidase YciB is a lipoprotein that localizes to the cell poles in a divisome-dependent manner

(2009) Marc Bramkamp   ARCHIVES OF MICROBIOLOGY

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

Curved FtsZ protofilaments generate bending forces on liposome membranes

(2009) Masaki Osawa et al.   EMBO JOURNAL

Bacillus subtilis Homologs of MviN (MurJ), the Putative Escherichia coli Lipid II Flippase, Are Not Essential for Growth

(2009) A. Fay et al.   JOURNAL OF BACTERIOLOGY

Role of Class A Penicillin-Binding Proteins in the Expression of  -Lactam Resistance in Enterococcus faecium

(2009) L. B. Rice et al.   JOURNAL OF BACTERIOLOGY

Regulation of cell wall morphogenesis inBacillus subtilisby recruitment of PBP1 to the MreB helix

(2009) Yoshikazu Kawai et al.   MOLECULAR MICROBIOLOGY

D-Amino Acids Govern Stationary Phase Cell Wall Remodeling in Bacteria

(2009) H. Lam et al.   SCIENCE

Identification of the L,D-Transpeptidases for Peptidoglycan Cross-Linking in Escherichia coli

(2008) S. Magnet et al.   JOURNAL OF BACTERIOLOGY

Growth of Escherichia coli: Significance of Peptidoglycan Degradation during Elongation and Septation

(2008) T. Uehara et al.   JOURNAL OF BACTERIOLOGY

The Peptidoglycan of Stationary-Phase Mycobacterium tuberculosis Predominantly Contains Cross-Links Generated by L,D-Transpeptidation

(2008) M. Lavollay et al.   JOURNAL OF BACTERIOLOGY

Bioinformatics identification of MurJ (MviN) as the peptidoglycan lipid II flippase in Escherichia coli

(2008) N. Ruiz   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell shape and cell-wall organization in Gram-negative bacteria

(2008) K. C. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstitution of Contractile FtsZ Rings in Liposomes

(2008) M. Osawa et al.   SCIENCE