Matrix metallopeptidase 9 targeted by hsa-miR-494 promotes silybin-inhibited osteosarcoma

MicroRNA-466 inhibits tumor growth and bone metastasis in prostate cancer by direct regulation of osteogenic transcription factor RUNX2

(2017) Melissa Colden et al.   Cell Death & Disease

miR-375-3p negatively regulates osteogenesis by targeting and decreasing the expression levels of LRP5 and β-catenin

(2017) Tianhao Sun et al.   PLoS One

miR-187-3p inhibits the metastasis and epithelial–mesenchymal transition of hepatocellular carcinoma by targeting S100A4

(2016) Changwei Dou et al.   CANCER LETTERS

Modulatory effects of silibinin in various cell signaling pathways against liver disorders and cancer – A comprehensive review

(2016) Navaneethakrishnan Polachi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

WNT/β-catenin signaling promotes VSMCs to osteogenic transdifferentiation and calcification through directly modulating Runx2 gene expression

(2016) Ting Cai et al.   EXPERIMENTAL CELL RESEARCH

RUNX2 promotes hepatocellular carcinoma cell migration and invasion by upregulating MMP9 expression

(2016) Qian Wang et al.   ONCOLOGY REPORTS

Soyasaponin bb protects rat hepatocytes from alcohol-induced oxidative stress by inducing heme oxygenase-1

(2016) Xiuying Liu et al.   Pharmacognosy Magazine

Intracellular and extracellular microRNA: An update on localization and biological role

(2016) Julia A. Makarova et al.   PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY

Osteosarcoma: Cells-of-Origin, Cancer Stem Cells, and Targeted Therapies

(2016) Ander Abarrategi et al.   Stem Cells International

Liver-targeting self-assembled hyaluronic acid-glycyrrhetinic acid micelles enhance hepato-protective effect of silybin after oral administration

(2015) Xiaofeng Han et al.   DRUG DELIVERY

miR-494 suppresses the progression of breast cancer in vitro by targeting CXCR4 through the Wnt/β-catenin signaling pathway

(2015) LINGQIN SONG et al.   ONCOLOGY REPORTS

miR-494 promotes cell proliferation, migration and invasion, and increased sorafenib resistance in hepatocellular carcinoma by targeting PTEN

(2015) KAI LIU et al.   ONCOLOGY REPORTS

miR-494 represses HOXA10 expression and inhibits cell proliferation in oral cancer

(2015) Tatiana N. Libório-Kimura et al.   ORAL ONCOLOGY

In vitro inhibitory effects of terpenoids from Chloranthus multistachys on epithelial–mesenchymal transition via down-regulation of Runx2 activation in human breast cancer

(2015) Jianjiang Fu et al.   PHYTOMEDICINE

Activation of microRNA-494-targeting Bmi1 and ADAM10 by silibinin ablates cancer stemness and predicts favourable prognostic value in head and neck squamous cell carcinomas

(2015) Yu-Chao Chang et al.   Oncotarget

Silibinin Suppresses Growth of Human Colorectal Carcinoma SW480 Cells in Culture and Xenograft through Down-regulation of β-Catenin-Dependent Signaling

(2015) Manjinder Kaur et al.   NEOPLASIA

Matrix metalloproteinase 9 (MMP-9) in osteosarcoma: Review and meta-analysis

(2014) Jing Wang et al.   CLINICA CHIMICA ACTA

Upregulation of miR-494 Inhibits Cell Growth and Invasion and Induces Cell Apoptosis by Targeting Cleft Lip and Palate Transmembrane 1-Like in Esophageal Squamous Cell Carcinoma

(2014) Ren Zhang et al.   DIGESTIVE DISEASES AND SCIENCES

miR-494 acts as an anti-oncogene in gastric carcinoma by targeting c-myc

(2014) Weiling He et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Silybin-Mediated Inhibition of Notch Signaling Exerts Antitumor Activity in Human Hepatocellular Carcinoma Cells

(2013) Song Zhang et al.   PLoS One

Cell-line authentication: End the scandal of false cell lines

(2012) John R. Masters   NATURE

Wnt/β-catenin signalling in prostate cancer

(2012) Robert M. Kypta et al.   Nature Reviews Urology

Pseudopodial Actin Dynamics Control Epithelial-Mesenchymal Transition in Metastatic Cancer Cells

(2010) Jay Shankar et al.   CANCER RESEARCH

Silibinin Suppresses TNF-α-Induced MMP-9 Expression in Gastric Cancer Cells through Inhibition of the MAPK Pathway

(2009) Sangmin Kim et al.   MOLECULES

Silibinin Suppresses Spontaneous Tumorigenesis in APC min/+ Mouse Model by Modulating Beta-Catenin Pathway

(2009) Subapriya Rajamanickam et al.   PHARMACEUTICAL RESEARCH

Effects and mechanisms of silibinin on human hepatocellular carcinoma xenografts in nude mice

(2009) Wei Cui et al.   WORLD JOURNAL OF GASTROENTEROLOGY

FHL2 mediates dexamethasone-induced mesenchymal cell differentiation into osteoblasts by activating Wnt/β-catenin signaling-dependent Runx2 expression

(2008) Zahia Hamidouche et al.   FASEB JOURNAL

Silibinin inhibits hypoxia-inducible factor-1α and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy

(2008) P García-Maceira et al.   ONCOGENE