Hdac7 promotes lung tumorigenesis by inhibiting Stat3 activation

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

HDAC7 inhibition resets STAT3 tumorigenic activity in human glioblastoma independently of EGFR and PTEN: new opportunities for selected targeted therapies

(2016) P Peixoto et al.   ONCOGENE

Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer

(2016) A E Witt et al.   ONCOGENE

HDACs and HDAC Inhibitors in Cancer Development and Therapy

(2016) Yixuan Li et al.   Cold Spring Harbor Perspectives in Medicine

The Opposing Function of STAT3 as an Oncoprotein and Tumor Suppressor Is Dictated by the Expression Status of STAT3  in Esophageal Squamous Cell Carcinoma

(2015) H.-F. Zhang et al.   CLINICAL CANCER RESEARCH

Mammalian Sterile 20-like Kinase 1 (Mst1) Enhances the Stability of Forkhead Box P3 (Foxp3) and the Function of Regulatory T Cells by Modulating Foxp3 Acetylation

(2015) Jiang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The transcriptional repressor HDAC7 promotes apoptosis and c-Myc downregulation in particular types of leukemia and lymphoma

(2015) B Barneda-Zahonero et al.   Cell Death & Disease

Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis

(2015) Beatrice Grabner et al.   Nature Communications

Acetylation of Snail Modulates the Cytokinome of Cancer Cells to Enhance the Recruitment of Macrophages

(2014) Dennis Shin-Shian Hsu et al.   CANCER CELL

Differential roles of STAT3 in the initiation and growth of lung cancer

(2014) J Zhou et al.   ONCOGENE

A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance

(2013) F. Santoro et al.   BLOOD

Both STAT1 and STAT3 are favourable prognostic determinants in colorectal carcinoma

(2013) C Gordziel et al.   BRITISH JOURNAL OF CANCER

STAT3 acetylation-induced promoter methylation is associated with downregulation of the ARHI tumor-suppressor gene in ovarian cancer

(2013) JIE LI et al.   ONCOLOGY REPORTS

The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells

(2012) Andrei Turtoi et al.   ANGIOGENESIS

Phosphorylation of signal transducer and activator of transcription 3 in soft tissue leiomyosarcoma is associated with a better prognosis

(2012) Nokitaka Setsu et al.   INTERNATIONAL JOURNAL OF CANCER

Correlation of Activated STAT3 Expression with Clinicopathologic Features in Lung Adenocarcinoma and Squamous Cell Carcinoma

(2012) Richeng Jiang et al.   Molecular Diagnosis & Therapy

Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation

(2012) H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STAT3 negatively regulates thyroid tumorigenesis

(2012) J. P. Couto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

research paper: Differential expression of HDAC3, HDAC7 and HDAC9 is associated with prognosis and survival in childhood acute lymphoblastic leukaemia

(2010) Daniel Antunes Moreno et al.   BRITISH JOURNAL OF HAEMATOLOGY

Hdac3 Is Essential for the Maintenance of Chromatin Structure and Genome Stability

(2010) Srividya Bhaskara et al.   CANCER CELL

Histone Deacetylase 7 Controls Endothelial Cell Growth Through Modulation of β-Catenin

(2010) Andriana Margariti et al.   CIRCULATION RESEARCH

Age- and Sex-Specific Genomic Profiles in Non–Small Cell Lung Cancer

(2010) William Mostertz   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Neuroprotection by Histone Deacetylase-7 (HDAC7) Occurs by Inhibition of c-junExpression through a Deacetylase-independent Mechanism

(2010) Chi Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of histone deacetylase 7 (HDAC7) in cancer cell proliferation: regulation on c-Myc

(2010) Caihua Zhu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Stat3 Is a Negative Regulator of Intestinal Tumor Progression in ApcMin Mice

(2009) Monica Musteanu et al.   GASTROENTEROLOGY

STAT3 inhibition of gluconeogenesis is downregulated by SirT1

(2009) Yongzhan Nie et al.   NATURE CELL BIOLOGY

Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors

(2009) Robert H Kutner et al.   Nature Protocols

Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase

(2009) Michel DuPage et al.   Nature Protocols

High Histone Deacetylase 7 (HDAC7) Expression Is Significantly Associated with Adenocarcinomas of the Pancreas

(2008) Mehdi Ouaïssi et al.   ANNALS OF SURGICAL ONCOLOGY

Probing the elusive catalytic activity of vertebrate class IIa histone deacetylases

(2008) Philip Jones et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

HDAC family: What are the cancer relevant targets?

(2008) Olaf Witt et al.   CANCER LETTERS

Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway

(2008) N. de la Iglesia et al.   GENES & DEVELOPMENT

Human HDAC7 Harbors a Class IIa Histone Deacetylase-specific Zinc Binding Motif and Cryptic Deacetylase Activity

(2008) Anja Schuetz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7

(2008) S. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA