Molecular Cloning, Structural Modeling and the Production of Soluble Triple-Mutated Diphtheria Toxoid (K51E/G52E/E148K) Co-expressed with Molecular Chaperones in Recombinant Escherichia coli

High level accumulation of soluble diphtheria toxin mutant (CRM197) with co-expression of chaperones in recombinant Escherichia coli

(2016) Pornpimol Mahamad et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Evaluation of the non-toxic mutant of the diphtheria toxin K51E/E148K as carrier protein for meningococcal vaccines

(2016) S. Pecetta et al.   VACCINE

The different roles of chaperone teams on over-expression of human-like collagen in recombinant Escherichia coli

(2014) Qingliang Jia et al.   Journal of the Taiwan Institute of Chemical Engineers

Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197

(2012) E. Malito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biochemical and biological characteristics of cross-reacting material 197 (CRM197), a non-toxic mutant of diphtheria toxin: Use as a conjugation protein in vaccines and other potential clinical applications

(2011) Michael Bröker et al.   BIOLOGICALS

Overexpression and purification of the recombinant diphtheria toxin variant CRM197 in Escherichia coli

(2011) Alessandra Stefan et al.   JOURNAL OF BIOTECHNOLOGY

Side effects of chaperone gene co-expression in recombinant protein production

(2010) Mónica Martínez-Alonso et al.   Microbial Cell Factories

How antibiotics kill bacteria: from targets to networks

(2010) Michael A. Kohanski et al.   NATURE REVIEWS MICROBIOLOGY

Overview of the development and current use of CRM197 conjugate vaccines for pediatric use

(2010) Henry R. Shinefield   VACCINE

Understanding the Differences between Genome Sequences of Escherichia coli B Strains REL606 and BL21(DE3) and Comparison of the E. coli B and K-12 Genomes

(2009) F. William Studier et al.   JOURNAL OF MOLECULAR BIOLOGY

Molecular Mechanisms of the Cytotoxicity of ADP-Ribosylating Toxins

(2008) Qing Deng et al.   Annual Review of Microbiology

Diphtheria toxin mutant CRM197 is an inhibitor of protein synthesis that induces cellular toxicity

(2007) Jian Qiao et al.   TOXICON