The phospho–caveolin-1 scaffolding domain dampens force fluctuations in focal adhesions and promotes cancer cell migration

Src-dependent phosphorylation of caveolin-1 Tyr-14 promotes swelling and release of caveolae

(2016) Adriana M. Zimnicka et al.   MOLECULAR BIOLOGY OF THE CELL

Extracellular matrix-specific Caveolin-1 phosphorylation on tyrosine 14 is linked to augmented melanoma metastasis but not tumorigenesis

(2016) Rina Ortiz et al.   Oncotarget

Molecular Characterization of Caveolin-induced Membrane Curvature

(2015) Nicholas Ariotti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integration of actin dynamics and cell adhesion by a three-dimensional, mechanosensitive molecular clutch

(2015) Lindsay B. Case et al.   NATURE CELL BIOLOGY

A plastic relationship between vinculin-mediated tension and adhesion complex area defines adhesion size and lifetime

(2015) Pablo Hernández-Varas et al.   Nature Communications

Galectin-3 Overrides PTRF/Cavin-1 Reduction of PC3 Prostate Cancer Cell Migration

(2015) Fanrui Meng et al.   PLoS One

Deciphering the Binding of Caveolin-1 to Client Protein Endothelial Nitric-oxide Synthase (eNOS)

(2014) Andy E. Trane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Online Quantitative Proteomics p-Value Calculator for Permutation-Based Statistical Testing of Peptide Ratios

(2014) David Chen et al.   JOURNAL OF PROTEOME RESEARCH

Vinculin Regulates the Recruitment and Release of Core Focal Adhesion Proteins in a Force-Dependent Manner

(2013) Alex Carisey et al.   CURRENT BIOLOGY

Vinculin Phosphorylation at Tyr1065Regulates Vinculin Conformation and Tension Development in Airway Smooth Muscle Tissues

(2013) Youliang Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vinculin–actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth

(2013) Ingo Thievessen et al.   JOURNAL OF CELL BIOLOGY

Global Impact ofSalmonellaPathogenicity Island 2-secreted Effectors on the Host Phosphoproteome

(2013) Koshi Imami et al.   MOLECULAR & CELLULAR PROTEOMICS

Galectin-3– and phospho-caveolin-1–dependent outside-in integrin signaling mediates the EGF motogenic response in mammary cancer cells

(2013) Cecile Boscher et al.   MOLECULAR BIOLOGY OF THE CELL

Caveolae as plasma membrane sensors, protectors and organizers

(2013) Robert G. Parton et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Force Fluctuations within Focal Adhesions Mediate ECM-Rigidity Sensing to Guide Directed Cell Migration

(2012) Sergey V. Plotnikov et al.   CELL

Structure-Based Reassessment of the Caveolin Signaling Model: Do Caveolae Regulate Signaling through Caveolin-Protein Interactions?

(2012) Brett M. Collins et al.   DEVELOPMENTAL CELL

Tyrosine-phosphorylated Caveolin-1 (Tyr-14) Increases Sensitivity to Paclitaxel by Inhibiting BCL2 and BCLxL Proteins via c-Jun N-terminal Kinase (JNK)

(2012) Ayesha N. Shajahan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphocaveolin-1 is a mechanotransducer that induces caveola biogenesis via Egr1 transcriptional regulation

(2012) Bharat Joshi et al.   JOURNAL OF CELL BIOLOGY

Nitric oxide–dependent Src activation and resultant caveolin-1 phosphorylation promote eNOS/caveolin-1 binding and eNOS inhibition

(2012) Zhenlong Chen et al.   MOLECULAR BIOLOGY OF THE CELL

Cellular Traction Stresses Increase with Increasing Metastatic Potential

(2012) Casey M. Kraning-Rush et al.   PLoS One

Evaluating Caveolin Interactions: Do Proteins Interact with the Caveolin Scaffolding Domain through a Widespread Aromatic Residue-Rich Motif?

(2012) Dominic P. Byrne et al.   PLoS One

Structural Characterization of the Caveolin Scaffolding Domain in Association with Cholesterol-Rich Membranes

(2011) Cody L. Hoop et al.   BIOCHEMISTRY

Cells Respond to Mechanical Stress by Rapid Disassembly of Caveolae

(2011) Bidisha Sinha et al.   CELL

Cooperative Role of Caveolin-1 and C-Terminal Src Kinase Binding Protein in C-Terminal Src Kinase-Mediated Negative Regulation of c-Src

(2011) A. T. Place et al.   MOLECULAR PHARMACOLOGY

Stromal Caveolin-1 Expression in Breast Carcinoma. Correlation with Early Tumor Recurrence and Clinical Outcome

(2011) Saba Mohamed El-Gendi et al.   PATHOLOGY & ONCOLOGY RESEARCH

Mechanotransduction In Vivo by Repeated Talin Stretch-Relaxation Events Depends upon Vinculin

(2011) Felix Margadant et al.   PLOS BIOLOGY

Mechanical Integration of Actin and Adhesion Dynamics in Cell Migration

(2010) Margaret L. Gardel et al.   Annual Review of Cell and Developmental Biology

Caveolin limits membrane microdomain mobility and integrin-mediated uptake of fibronectin-binding pathogens

(2010) C. Hoffmann et al.   JOURNAL OF CELL SCIENCE

Focal-adhesion targeting links caveolin-1 to a Rac1-degradation pathway

(2010) M. Nethe et al.   JOURNAL OF CELL SCIENCE

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

(2010) Carsten Grashoff et al.   NATURE

Nanoscale architecture of integrin-based cell adhesions

(2010) Pakorn Kanchanawong et al.   NATURE

Changes in caveolae, caveolin, and polymerase 1 and transcript release factor (PTRF) expression in prostate cancer progression

(2010) M.L. Gould et al.   PROSTATE

Stromal Cell Expression of Caveolin-1 Predicts Outcome in Breast Cancer

(2009) Erica K. Sloan et al.   AMERICAN JOURNAL OF PATHOLOGY

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Filamin A Regulates Caveolae Internalization and Trafficking in Endothelial Cells

(2009) Maria Sverdlov et al.   MOLECULAR BIOLOGY OF THE CELL

Stretching Single Talin Rod Molecules Activates Vinculin Binding

(2009) A. del Rio et al.   SCIENCE

Caveolin-1 in tumor progression: the good, the bad and the ugly

(2008) Jacky G. Goetz et al.   CANCER AND METASTASIS REVIEWS

Phosphorylated Caveolin-1 Regulates Rho/ROCK-Dependent Focal Adhesion Dynamics and Tumor Cell Migration and Invasion

(2008) B. Joshi et al.   CANCER RESEARCH

Concerted regulation of focal adhesion dynamics by galectin-3 and tyrosine-phosphorylated caveolin-1

(2008) Jacky G. Goetz et al.   JOURNAL OF CELL BIOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Traction Dynamics of Filopodia on Compliant Substrates

(2008) C. E. Chan et al.   SCIENCE