Pharmacological targeting of HSP90 with 17-AAG induces apoptosis of myogenic cells through activation of the intrinsic pathway

Bit-1 is an essential regulator of myogenic differentiation

(2015) G. S. Griffiths et al.   JOURNAL OF CELL SCIENCE

Apoptosis in differentiating C2C12 muscle cells selectively targets Bcl-2-deficient myotubes

(2013) Christian Schöneich et al.   APOPTOSIS

DNA damage response by single-strand breaks in terminally differentiated muscle cells and the control of muscle integrity

(2012) P Fortini et al.   CELL DEATH AND DIFFERENTIATION

Pharmacological inhibition of HSP90 activity negatively modulates myogenic differentiation and cell survival in C2C12 cells

(2011) Akira Wagatsuma et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Bupivacaine causes cytotoxicity in mouse C2C12 myoblast cells: involvement of ERK and Akt signaling pathways

(2010) Joseph M Maurice et al.   ACTA PHARMACOLOGICA SINICA

17-Allylamino-17-demethoxygeldanamycin induces downregulation of critical Hsp90 protein clients and results in cell cycle arrest and apoptosis of human urinary bladder cancer cells

(2010) Panagiotis K Karkoulis et al.   BMC CANCER

Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes

(2010) H. Takai et al.   GENES & DEVELOPMENT

Targeting heat shock protein 72 enhances Hsp90 inhibitor-induced apoptosis in myeloma

(2010) E L Davenport et al.   LEUKEMIA

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

(2010) Mikko Taipale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hsp90 inhibitors, GA and 17AAG, lead to ER stress-induced apoptosis in rat histiocytoma

(2009) Aftab Taiyab et al.   BIOCHEMICAL PHARMACOLOGY

Acquired Resistance to 17-Allylamino-17-Demethoxygeldanamycin (17-AAG, Tanespimycin) in Glioblastoma Cells

(2009) N. Gaspar et al.   CANCER RESEARCH

Apoptotic signaling induced by H2O2-mediated oxidative stress in differentiated C2C12 myotubes

(2009) Parco M. Siu et al.   LIFE SCIENCES

Mitochondrial membrane permeabilization in neuronal injury

(2009) Lorenzo Galluzzi et al.   NATURE REVIEWS NEUROSCIENCE

Skeletal Muscle Differentiation Evokes Endogenous XIAP to Restrict the Apoptotic Pathway

(2009) Michelle I. Smith et al.   PLoS One

Bax signaling regulates palmitate-mediated apoptosis in C2C12 myotubes

(2008) Jonathan M. Peterson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Age-related activation of mitochondrial caspase-independent apoptotic signaling in rat gastrocnemius muscle

(2008) Emanuele Marzetti et al.   MECHANISMS OF AGEING AND DEVELOPMENT

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

(2008) Jerry E. Chipuk et al.   TRENDS IN CELL BIOLOGY