Journal
MOLECULAR AND BIOCHEMICAL PARASITOLOGY
Volume 215, Issue -, Pages 23-29Publisher
ELSEVIER
DOI: 10.1016/j.molbiopara.2017.01.004
Keywords
Filaria; Parasitic nematodes; Genomics; Transcriptomics
Categories
Ask authors/readers for more resources
Human filarial infections are a leading cause of morbidity in the developing world. While a small arsenal of drugs exists to treat these infections, there remains a tremendous need for the development of additional interventions. Recent genome sequences and transcriptome analyses of filarial nematodes have provided novel biological insight and allowed for the prediction of novel drug targets as well as potential vaccine candidates. In this review, we discuss the currently available data, insights gained into the metabolism of these organisms, and how the filaria field can move forward by leveraging these data. (C) 2017 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available